Pregnancy After Kidney Transplantation: Graft, Mother, and Newborn Complications

Rocha, Ana; Cardoso, Ana Sofia; Malheiro, Jorge; Martins, La Salete; Fonseca, Isabel; Braga, Jorge; Henriques, António Castro

doi:10.1016/j.transproceed.2013.02.006

Cited by 23 publications

(20 citation statements)

References 11 publications

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“…Although cesarean section has not been an absolute indication in this group, the rate is higher than in the general population, which was also observed in our study, due to preterm labor and maternal complications such as hypertension, preeclampsia and worsening renal function [26,27,28,29]. We should also note that cesarean section is generally a safe procedure, but extreme attention must be paid to avoid ureter and graft injury.…”

Section: Discussionsupporting

confidence: 57%

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

Akar

Ozekinci

Sanhal

et al. 2014

Gynecol Obstet Invest

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Background: We reported pregnancy outcomes after kidney transplantation in a single transplant center. Methods: We reviewed the perinatal outcomes of female kidney transplant patients of reproductive age (18-40 years) from 1987 to 2011. Results: A total of 246 patients were reviewed. Of these, 43 women registered a pregnancy following kidney transplantation. The mean patient age was 31.3 ± 4.2 years (range 24-40). The mean transplant-conception interval was 35.9 ± 12.6 months (range 24-120); 9 patients had a cadaveric allograft. The human leukocyte antigen match was ≥3/6 for 34 patients. The rate of live births was 29/43 (67.4%), miscarriage 10/43 (23.2%), preterm delivery 7/29 (24.1%), preeclampsia 5/29 (17.2%), and intrauterine growth retardation 2/29 (6.9%). Overall, 3/29 patients (10.3%) received a blood transfusion during pregnancy due to persistent symptomatic anemia, despite iron replacement and erythropoietin therapy; 24 patients (82%) had a cesarean section delivery; 3 patients had kidney rejection during pregnancy, with 2 occurring during the 6th postpartum month. Conclusion: Pregnancy should be considered a high risk in renal transplant recipients, necessitating close follow-up.

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Section: Discussionsupporting

confidence: 57%

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

Akar

Ozekinci

Sanhal

et al. 2014

Gynecol Obstet Invest

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“…Kidney transplant recipients are advised to delay pregnancy for a minimum of 1 year after transplant to reduce potential neonatal and maternal complications. 74 Different methods of contraception can be used after kidney transplant. Combined hormonal contraceptives are commonly used for their effectiveness.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Yousif

Bridson

Halawa³

2016

Exp Clin Transplant

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There is a misconception among transplant clinicians that contraception after a successful renal transplant is challenging. This is partly due to the complex nature of transplant patients, where immunosuppression and graft dysfunction create major concerns. In addition, good evidence regarding contraception and transplant is scarce, with most of the evidence extrapolated from observational and case-controlled studies, thus adding to the dilemma of treating these patients. In this review, we closely analyzed the different methods of contraception and critically evaluated the efficacy of the different options for contraception after kidney transplant. We conclude that contraception after renal transplant is successful with acceptable risk. A multidisciplinary team approach involving obstetricians and transplant clinicians to decide the appropriate timing for conception is recommended. Early counseling on contraception is important to reduce the risk of unplanned pregnancies, improve pregnancy outcomes, and reduce maternal complications in patients after kidney transplant. To ascertain appropriate advice on the method of contraception, individualizing the method of contraception according to a patient's individual risks and expectations is essential.

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“…Although graft dysfunction and obstructive uropathy are reported in pregnant patients with kidney transplantation (9), studies compared the long -term outcomes of pregnancy on transplanted kidney with nulliparous transplanted controls did not show significant differences in the function or survival of graft in long term (10)(11)(12)(13)(14)(15)(16)(17) (Table 1). Graft function in the 10 -year period was similar between patients with pregnancy history and controls (12)(13)(14)(15).…”

Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 97%

“…Rosha et al, reported no differences between the median of estimated glomerular filtration rate Copyright © 2018, Nephro-Urology Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited (eGFR) before pregnancy and that of the time of follow -up at the last postpartum visits (17).…”

Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 99%

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Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

Horstmann¹

2011

Nephro Urol Mon

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Context: The current study aimed at providing an evidence -based and up-to-date review of the literature regarding the assessment and outcomes of pregnancy in patients with renal transplant. Design: It was a review of the current literature. Conclusions: According to the current study findings, the function or survival of renal allograft was not adversely affected by getting pregnant. Therefore, ideal care for these patients needs a multidisciplinary approach including maternal-fetal medicine, nephrology, and neonatology specialists.

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Pregnancy After Kidney Transplantation: Graft, Mother, and Newborn Complications

Cited by 23 publications

References 11 publications

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

Untitled

Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

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