Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)

“…PE was ruled out without CTPA in women deemed to be at low PE risk according to the combination of the algorithm and D-dimer results. At 3 months, only one woman with PE excluded on the basis of the algorithm developed a popliteal DVT (0.21%, 95% CI 0.04-1.2) and no women developed PE [391].…”

“…Formal diagnostic assessment with validated methods is recommended if PE is suspected during pregnancy or in the post-partum period [388,391]. B I…”

“…Thrombolysis or surgical embolectomy should be considered for pregnant women with high-risk PE [421]. C III D-dimer measurement and clinical prediction rules should be considered to rule out PE during pregnancy or the post-partum period [388,391].…”

Pregnancy-adapted YEARS algorithm: can YEARS do more for pregnant women?

“…A study by van der Pol et al [13] entitled "Pregnancyadapted YEARS algorithm for diagnosis of suspected pulmonary embolism" has been published in the New England Journal of Medicine [13]. The study was a multi-center, international study conducted at 18 hospitals.…”

“…It includes three clinical criteria (clinical signs of DVT, haemoptysis, and whether PE is the most likely diagnosis) and one laboratory criteria (D-dimer value) to determine the need for CTPA (figure 1) [12]. With the creation and validation of this algorithm, a step forward was taken and with the algorithms adaptation to pregnant women [13].…”