2020
DOI: 10.1101/2020.02.27.968719
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Prefrontal responses during proactive and reactive inhibition are differentially impacted by stress in anorexia and bulimia nervosa

Abstract: Background: Binge-eating is a distressing, transdiagnostic eating disorder symptom associated with impulsivity, particularly in negative mood states. Neuroimaging studies of bulimia nervosa (BN) report reduced activity in fronto-striatal regions implicated in self-regulatory control. However, it remains unknown if negative affective states, including stress, impair self-regulation, and, if so, whether such self-regulatory deficits generalize to binge-eating in underweight individuals (i.e., the bingeing/purgin… Show more

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“…Increased compulsivity, manifesting as compulsive restriction of food intake and compulsive exercise is also in line with previous research ( Davis & Kaptein, 2006 ; Godier & Park, 2014 ), as well as a higher level of negative urgency impulsive, particularly in cohorts of heightened impulsivity during negative emotional states (e.g. binge/purging AN or BN) ( Westwater et al, 2019 ). The increased level of PUI is also in line with previous research.…”
Section: Discussionsupporting
confidence: 90%
“…Increased compulsivity, manifesting as compulsive restriction of food intake and compulsive exercise is also in line with previous research ( Davis & Kaptein, 2006 ; Godier & Park, 2014 ), as well as a higher level of negative urgency impulsive, particularly in cohorts of heightened impulsivity during negative emotional states (e.g. binge/purging AN or BN) ( Westwater et al, 2019 ). The increased level of PUI is also in line with previous research.…”
Section: Discussionsupporting
confidence: 90%