Prefrontal modulation during chewing performance in occlusal dysesthesia patients: a functional near-infrared spectroscopy study

Abstract

Objectives Neuropsychological associations can be considerable in occlusal dysesthesia (OD) patients who routinely complain of persistent occlusal discomfort, and somatization effects in the superior medial prefrontal cortex and the temporal and parietal regions are also present. However, the relationship between physical activity, i.e., chewing, prefrontal cognitive demand, and psychiatric states in OD patients remains unclear. We investigated this relationship in this study. Materials and methods OD patients (n = 15) and healthy control (n = 15; HC) subjects were enrolled in this study. Occlusal contact, chewing activities of the masticatory muscles, prefrontal activities, and psychiatric states such as depression and somatization, of the participants were evaluated. Functional near-infrared spectroscopy was used to determine prefrontal hemodynamics and the Symptom Checklist-90-R was used to score the psychiatric states. Results We observed a significant association between prefrontal deactivation during chewing and somatization subscales in OD patients. Further, there were no significant differences with regard to the occlusal state and chewing physical activities between the OD patients and HC subjects. Conclusions Chewing-related prefrontal deactivation may be associated with somatization severity in OD patients. Clinical relevance fNIRS is a functional imaging method that uses the principal of neuro-vascular couplings. It is applicable for evaluation of psychiatric state based on prefrontal cortex blood flow in patients with psychiatric disorders.

Uncomfortable bite - is it always a dental problem?

“…Narita et al 8 also confirmed strong somatization in patients with symptoms of dysesthesia. The test methods included evaluation of occlusal contacts, masticatory muscles activity, imaging of the prefrontal cortex hemodynamics (used to assess the mental state of patients with mental disorders) and the use of the Symptom Checklist-90-R (SCL-90-R) test.…”

“…Znaleziono 43 artykuły, z których po ocenie tytułów i streszczeń wyodrębniono 4 oryginalne prace, spełniające ustalone kryteria włączenia. [6][7][8][9] Przeglądając piśmiennictwo wybranych artykułów zakwalifikowano jeszcze jedną pracę. 10…”

“…A total of forty-three articles were found, of which, after evaluation of the titles and abstracts, four original works were selected, meeting the predetermined inclusion criteria. [6][7][8][9] While reviewing the reference literature of selected articles, one more work was qualified. 10…”

Prefrontal Consolidation and Compensation as a Function of Wearing Denture in Partially Edentulous Elderly Patients

“…A previous report presented averaged recording data for masticatory muscle activities and fNIRS obtained during both right-and left-side chewing in order to exclude functional laterality (Kamiya et al, 2016), and the present study also averaged the bilateral fNIRS data. Recently, the dissociated prefrontal cortex activities were presented during chewing performance in patients complaining of oral dysesthesia as compared with healthy controls, even though jaw muscle activities were not different between those two groups (Narita et al, 2019).…”

“…Functional near-infrared spectroscopy has been used to reveal the hemodynamic response to stimulus-induced cortical activation in order to evaluate the neurobiology in exercise and cognition (Bhambhani et al, 2006;Tsujii et al, 2013;Moriya et al, 2016), and chewing cognition was also examined by fNIRS in both young and aged subjects (Hasegawa et al, 2013;Kamiya et al, 2016;Yokoyama et al, 2017) as well as psychiatric patients with persistent occlusal dysesthesia (Narita et al, 2019). fNIRS Abbreviations: AD, anterior digastric; BA, pars triangularis Broca's area; DLPFC, dorsolateral prefrontal cortex; EMG, electromyography; FPA, frontopolar area; fMRI, functional magnetic resonance imaging; fNIRS, functional near-infrared spectroscopy; IPG, inferior prefrontal gyrus; Mm, masseter; OFC, orbitofrontal cortex; Ta, anterior temporal.…”