Preference, satisfaction and errors with two dry powder inhalers in patients with COPD

Abstract

After 2 weeks' practice, patients preferred and were more willing to continue using Genuair than HandiHaler. Genuair was associated with higher patient satisfaction and fewer critical errors than HandiHaler.

Inhaler Operability and Patient Satisfaction Regarding Genuair® and Respimat® Inhalers for Chronic Obstructive Pulmonary Disease: A Randomized Crossover Study

“…Patients using the Genuair devices required significantly less instruction, and retained that knowledge better after two weeks (significantly higher correct operation rate and fewer errors). A previous study found that significantly fewer patients experienced a critical error, defined as an error affecting drug delivery, with the Genuair device compared to the HandiHaler device (2.9% vs 19%, respectively, p\0.0001) [8]. These results suggest that the Genuair device is generally well tolerated in patients with COPD, and there were fewer errors affecting drug delivery than in both tiotropium devices.…”

“…A previous study found that the preference rate was 45.6% for Respimat and 17.5% for HandiHaler, or in other words, Respimat was approximately 2.6 times more preferable than HandiHaler [13]. Another study found that the preference was 65.1% for Genuair and 16.6% for HandiHaler [8]. Since Respimat was 2.6 times more preferable than HandiHaler, the preference for Respimat was estimated to be 43% (16.6% 9 2.6).…”

“…When assessing patient willingness to continue with a device, more patients were willing to continue with Genuair than HandiHaler, as indicated by a higher mean rating in the preference scale at week 6 (88.8 vs 45.4, p\0.0001) [7]. An open-label, randomized, crossover study by van der Palen et al also compared patient preference, satisfaction, and the number of errors related to inhaler use between the Genuair and HandiHaler in patients with moderate to severe COPD [8]. Overall, more patients were significantly more satisfied with and preferred Genuair to HandiHaler (79.1% vs 20.9%, p\0.0001).…”

The Global Usability Score: A Novel Comprehensive Tool for Assessing, Ranking, and Compare Usability of Inhalers in Patients Requiring Airway Treatments

“…As a consequence, the causes of patients' incorrect inhalation procedures and the determinants of patients' preference and acceptance had been extensively investigated, mainly being the patient's confidence and beliefs highly valued and regarded as the very crucial steps of the process to improve [9,15].…”

“…In particular, the determinants of patients' incorrect inhalation procedures [7,8] and those of patients' preference, acceptance, and satisfaction focused the attention of the majority of researchers [9][10][11][12][13][14][15]. The primary role of patients' viewpoint was then highly valued in recent years, even if the attempts to quantify objectively the correspondence between patients' beliefs and real usability in real life by means of specific instruments were only episodically pursued [11,[16][17][18][19].…”