Preface

Baltzer, N.; Copponnex, Thierry

doi:10.1016/b978-0-85709-434-6.50014-7

Cited by 4 publications

(5 citation statements)

References 0 publications

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“…Two different intermetallic phases were identified in the microstructure presented in Figure 1 b. Based on the phase analysis results, introduced in Table 2 , Mg 2 Ca intermetallic phase was identified, in the alloy microstructure (see Figure 1 b), typical for Mg-Ca systems [ 8 ]. The second intermetallic phase present in the microstructure, identified based on the chemical composition measured by the EDX system (see Table 2 and literature data [ 8 ]), was Ca 2 Mg 6 Zn 3 intermetallic compound (light particles in Figure 1 b).…”

Section: Microstructure Characteristicsmentioning

confidence: 99%

“…Important advantages predetermining magnesium alloys to be chosen for many usages are their low density, high specific strength and stiffness, and high damping capacity [ 1 , 2 , 3 , 4 , 5 ]. Magnesium alloys have also excellent biomechanical properties for many applications and biocompatibility which allow adopting them as materials convenient for implants in the orthopedics and trauma therapy [ 2 , 3 , 4 , 6 , 7 , 8 ]. The most restrictive disadvantages of magnesium and its alloys are poor formability and limited ductility at room temperature, which are a consequence of their hexagonal close-packed (hcp) structure with the restricted number of available easy-slip systems and presence of intermetallic phases [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Influence of Processing Techniques on Microstructure and Mechanical Properties of a Biodegradable Mg-3Zn-2Ca Alloy

et al. 2016

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New Mg-3Zn-2Ca magnesium alloy was prepared using different processing techniques: gravity casting as well as squeeze casting in liquid and semisolid states. Materials were further thermally treated; thermal treatment of the gravity cast alloy was additionally combined with the equal channel angular pressing (ECAP). Alloy processed by the squeeze casting in liquid as well as in semisolid state exhibit improved plasticity; the ECAP processing positively influenced both the tensile and compressive characteristics of the alloy. Applied heat treatment influenced the distribution and chemical composition of present intermetallic phases. Influence of particular processing techniques, heat treatment, and intermetallic phase distribution is thoroughly discussed in relation to mechanical behavior of presented alloys.

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Section: Microstructure Characteristicsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Influence of Processing Techniques on Microstructure and Mechanical Properties of a Biodegradable Mg-3Zn-2Ca Alloy

et al. 2016

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“…Nanoparticles (NPs) are sub-micrometer sized particles, often smaller than 200 nm which exhibit unique physical and chemical properties [ 8 , 9 , 10 ]. Among the various NP systems, gold nanoparticles (GNPs) have been used extensively in the field of nanomedicine and cancer research for imaging and therapeutic purposes [ 11 , 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Determining the Radiation Enhancement Effects of Gold Nanoparticles in Cells in a Combined Treatment with Cisplatin and Radiation at Therapeutic Megavoltage Energies

Yang

Bromma

Sung

et al. 2018

Cancers

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Combined use of chemotherapy and radiation therapy is commonly used in cancer treatment, but the toxic effects on normal tissue are a major limitation. This study assesses the potential to improve radiation therapy when combining gold nanoparticle (GNP) mediated radiation sensitization with chemoradiation compared to chemoradiation alone. Incorporation of GNPs with 2 Gy, 6 MV (megavoltage) radiation resulted in a 19 ± 6% decrease in survival of MDA-MB-231 cells. Monte-Carlo simulations were performed to assess dosimetric differences in the presence of GNPs in radiation. The results show that physics dosimetry represents a small fraction of the observed effect. The survival fraction of the cells exposed to GNPs, cisplatin, and radiation was 0.16 ± 0.007, while cells treated with cisplatin and radiation only was 0.23 ± 0.011. The presence of GNPs resulted in a 30 ± 6% decrease in the survival, having an additive effect. The concentration of the GNPs and free drug used for this study was 0.3 and 435 nM, respectively. These concentrations are relatively lower and achievable in an in vivo setting. Hence, the results of our study would accelerate the incorporation of GNP-mediated chemoradiation into current cancer therapeutic protocols in the near future.

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“…The network formers are assumed to be SiO 2 and the network modifiers, CaO, Na 2 O, and P 2 O 5 . Ag 2 O generally behaves as a network modifier but can change its role to that of a network former [ 58 ]. This usually occurs if Ag 2 O is present in high concentrations, or if metallic silver particles form during glass synthesis.…”

Section: Methodsmentioning

confidence: 99%

Rapidly-Dissolving Silver-Containing Bioactive Glasses for Cariostatic Applications

Rodriguez

Alhalawani

Arshad

2018

JFB

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A novel bioactive glass series containing incremental amounts of silver oxide was synthesized, ground down, and subsequently incorporated into a dentifrice for the purpose of reducing the incidence of dental caries and lesion formation. Three glasses were synthesized using the melt quench route: Si-Control (70SiO2–12CaO–3P2O5–15Na2O, mol %), Si-02 and Si-05, where 0.2 and 0.5 mol % Ag2O were substituted, respectively, for SiO2 in Si-Control. The glasses were then ground, sieved, characterized, and dissolved in Tris buffer solution (pH = 7.30) for 6, 12, and 24 h, with the pH of the resultant solution being recorded and the ions that were released into solution quantified. Samples of each glass were subsequently embedded into a non-fluoridated, commercially available toothpaste which was then used to brush resin-mounted lamb molars which, up to the point of testing, had been stored in a 1.0 M HCl solution. Knoop microhardness measurements of the molars were recorded before and after brushing to determine the presence of remineralization on the surface of the teeth (surface hardness loss of 37%, 35%, and 34% for Si-Control, Si-02 and Si-05, respectively, after 24 h). Four oral cavity bacterial strains were isolated through swabs of the inner cheek, gums, and teeth surfaces of three volunteers, and placed on agar discs. Of each glass, 0.5 g was placed onto the discs, and the resultant inhibition zones were measured after 6, 12, and 24 h. Si-05 performed better than Si-02 on two strains after 24 h, while exhibiting similar behavior for the remaining two strains after 24 h; the largest inhibition zone measured was 2.8 mm, for Si-05 after 12 h. Si-Control exhibited no antibacterial effect at any time point, providing evidence for the role of silver oxide as the antibacterial component of these glasses.

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Preface

Cited by 4 publications

References 0 publications

Influence of Processing Techniques on Microstructure and Mechanical Properties of a Biodegradable Mg-3Zn-2Ca Alloy

Influence of Processing Techniques on Microstructure and Mechanical Properties of a Biodegradable Mg-3Zn-2Ca Alloy

Determining the Radiation Enhancement Effects of Gold Nanoparticles in Cells in a Combined Treatment with Cisplatin and Radiation at Therapeutic Megavoltage Energies

Rapidly-Dissolving Silver-Containing Bioactive Glasses for Cariostatic Applications

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