Preface

Lissauer, Tom; Clayden, Graham

doi:10.1016/b978-0-7234-3565-5.00033-9

Cited by 29 publications

(40 citation statements)

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“…While in high-income countries many tools have been developed and validated to evaluate children’s psychomotor development, there is a shortage of appropriate assessment tools for populations living in low-income settings [ 58 , 59 ]. In this study, an adapted and simplified test was used, which might be difficult to compare with that used in other studies [ 30 ]. In the two previously described trials carried out in Thailand, no significant differences were found in neurological development assessed by the Denver Developmental Screening Test at 24 mo of age between the children of women who received MQ-AS versus quinine for the treatment of malaria in pregnancy, and mean ages to sit and to crawl were significantly younger in the children of women given MQ versus placebo as malaria prophylaxis [ 27 , 28 , 60 ].…”

Section: Discussionmentioning

confidence: 99%

“…Women were asked to bring their children to the study health facility when the babies were 1 mo of age or coinciding with the first Expanded Program on Immunization visit at 6 wk, and also at 9 and 12 mo of age. At each visit, the baby’s weight and length were recorded, and psychomotor development was evaluated following a simplified adapted protocol that included assessment of gross and fine motor skills, language, audition, and social skills [ 30 ]. Participants who did not attend scheduled study visits were visited at home and encouraged to attend the health facility for completion of study visits.…”

Section: Methodsmentioning

confidence: 99%

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Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

et al. 2016

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BackgroundLittle is known about the effects of intermittent preventive treatment of malaria in pregnancy (IPTp) on the health of sub-Saharan African infants. We have evaluated the safety of IPTp with mefloquine (MQ) compared to sulfadoxine-pyrimethamine (SP) for important infant health and developmental outcomes.Methods and FindingsIn the context of a multicenter randomized controlled trial evaluating the safety and efficacy of IPTp with MQ compared to SP in pregnancy carried out in four sub-Saharan countries (Mozambique, Benin, Gabon, and Tanzania), 4,247 newborns, 2,815 born to women who received MQ and 1,432 born to women who received SP for IPTp, were followed up until 12 mo of age. Anthropometric parameters and psychomotor development were assessed at 1, 9, and 12 mo of age, and the incidence of malaria, anemia, hospital admissions, outpatient visits, and mortality were determined until 12 mo of age. No significant differences were found in the proportion of infants with stunting, underweight, wasting, and severe acute malnutrition at 1, 9, and 12 mo of age between infants born to women who were on IPTp with MQ versus SP. Except for three items evaluated at 9 mo of age, no significant differences were observed in the psychomotor development milestones assessed. Incidence of malaria, anemia, hospital admissions, outpatient visits, and mortality were similar between the two groups. Information on the outcomes at 12 mo of age was unavailable in 26% of the infants, 761 (27%) from the MQ group and 377 (26%) from the SP group. Reasons for not completing the study were death (4% of total study population), study withdrawal (6%), migration (8%), and loss to follow-up (9%).ConclusionsNo significant differences were found between IPTp with MQ and SP administered in pregnancy on infant mortality, morbidity, and nutritional outcomes. The poorer performance on certain psychomotor development milestones at 9 mo of age in children born to women in the MQ group compared to those in the SP group may deserve further studies.Trial registrationClinicalTrials.gov NCT00811421

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

et al. 2016

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“…The same virus was isolated from the CSF. Adenoviruses are a common cause of childhood infection [1] with protean presentation. The portals of entry are the respiratory and feco-oral routes.…”

Section: Discussionmentioning

confidence: 99%

Post-adenoviral parasympathetic dysautonomia in a child: a case report

McLoughlin¹,

Martinez²

2010

J Med Case Rep

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IntroductionThis is the first reported case of adenoviral meningoencephalitis that was complicated by persistent parasympathetic dysautonomia, which clinically either stimulated or inhibited its activity.Case presentationA 7-year-old Caucasian girl presented to our hospital in March 2008 with a three day history of upper respiratory infection. Her condition worsened and she was placed on ventilator support for two weeks. Her recovery was complicated by a persistent selective parasympathetic dysautonomia. Her past medical history was unremarkable.ConclusionsTo the best of our knowledge this is the first case of an adenoviral infection in a child which was complicated after recovery from an acute meningoencephalitis and peripheral neuropathy.

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“…zolpidem, zopiclone) are mainly prescribed for older children and teen-agers [ 3 , 4 ]. In Norway, the antihistamine alimemazine (an aliphatic phenothiazine) is the most used sleep inducing drug in infants and toddlers, despite not being approved for the age group less than 2 years of age [ 1 , 3 , 5 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data

Holdø

Bramness²,

Handal

et al. 2017

J of Pharm Policy and Pract

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BackgroundDifferent methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This study aimed to investigate the agreement between mother-reported questionnaire-based data and prescription record data for hypnotic drugs in children aged 0–18 months. The agreement was compared to the agreement for a group of antiepileptic drugs.MethodsPrescription record data were collected from the Norwegian prescription database for 47,413 children also surveyed in the Norwegian mother and child cohort between 2005 and 2009. Agreement between in the two data sources was calculated using Cohens Kappa. Multinomial logistic regression was used to calculate the effect of sociodemographic variables on discrepancies in data sources.ResultsThe agreement between mother-reported and dispensed hypnotics was less than 50% for all hypnotics. Sensitivity of reporting increased with number of filled prescriptions. The agreement of antiepileptic drugs was 92.9% in the same population. Of several sociodemographic factors only paternal educational level and maternal work situation was significantly related to agreement between prescription record and survey data.ConclusionThere was a moderate agreement between reported use and dispensed hypnotic drugs for infants and toddlers. Results indicate that sociodemographic factors play only a minor role in explaining discrepancy.Electronic supplementary materialThe online version of this article (10.1186/s40545-017-0117-7) contains supplementary material, which is available to authorized users.

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Preface

Cited by 29 publications

References 0 publications

Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

Post-adenoviral parasympathetic dysautonomia in a child: a case report

Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data

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