Preemptive intraarticular tramadol for pain control after arthroscopic knee surgery

Tuncer, Bilge; Babacan, Avni; Arslan, Mustafa

doi:10.1097/00115550-200409002-00177

Cited by 12 publications

(12 citation statements)

References 20 publications

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“…However, there was no significant difference between these values, which suggests that morphine had a similar effect on nociceptive pain although it was more potent than tramadol. 21,22 It is obviously clear that opioid analgesics had lost their effect by 6 months, as there was no difference between the groups.…”

Section: Discussionmentioning

confidence: 99%

Comparative study in patients with symptomatic internal derangements of the temporomandibular joint: analgesic outcomes of arthrocentesis with or without intra-articular morphine and tramadol

Sipahi¹,

Satilmis²,

Basa³

2015

British Journal of Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Comparative study in patients with symptomatic internal derangements of the temporomandibular joint: analgesic outcomes of arthrocentesis with or without intra-articular morphine and tramadol

Sipahi¹,

Satilmis²,

Basa³

2015

British Journal of Oral and Maxillofacial Surgery

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“…All six studies measured pain scores post‐knee arthroscopy. Four of the six studies measured pain scores at ≤1 h . On qualitative analysis there was high‐level evidence with all studies showing a significantly lower pain score in the tramadol group.…”

Section: Resultsmentioning

confidence: 98%

Tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy: a systematic review and meta‐analysis

Ryan

Hodge

Holyoak

et al. 2019

ANZ Journal of Surgery

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Background Arthroscopic knee surgery is a common technique used in Australia. Post‐operative pain is common and can lead to delayed discharge and impair early mobilization. Use of local anaesthesia can reduce pain while avoiding systemic side effects. This systematic review and meta‐analysis aimed to establish the use of tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy in the current literature. Methods Two independent reviewers performed a systematic search of four databases, where 24 articles were identified with six studies (four high‐quality and two low‐quality randomized controlled trials), with a total of 334 patients were included for analysis. RevMan 5.3 software (The Nordic Cochrane Centre, Copenhagen, Denmark) was used to perform the data analysis. The studies included focused on outcomes such as pain scores, breakthrough analgesia, total analgesia, time to discharge and adverse events related to the use of tramadol as an adjunctive therapy. Results This study found that using tramadol as an adjunct to intra‐articular local anaesthetic infiltration in arthroscopic knee surgery reduced post‐operative pain and increased time to breakthrough analgesia without an increase in side effects. Conclusion This meta‐analysis suggests that tramadol is an efficacious adjunct for use in intra‐articular local anaesthetic infiltration following arthroscopic knee surgery.

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“…There are only two studies using tramadol and local anesthetic combination intra-articularly. In both studies, bupivacaine was used as local anesthetic ( 9 , 35 ). In Tuncer et al study ( 35 ), IA combination of 0.25% bupivacaine and 100 mg of tramadol produced significantly lower postoperative VAS scores than 0.25% bupivacaine alone did.…”

Section: Discussionmentioning

confidence: 99%

“…In both studies, bupivacaine was used as local anesthetic ( 9 , 35 ). In Tuncer et al study ( 35 ), IA combination of 0.25% bupivacaine and 100 mg of tramadol produced significantly lower postoperative VAS scores than 0.25% bupivacaine alone did. In a recent study, Zeidan et al ( 5 ) found that a combination of tramadol (100 mg) with 0.25% bupivacaine after arthroscopic knee surgery provides a lower VAS pain scores, a longer duration of analgesia, and a decrease in the 24-hour consumption of rescue analgesia without any side effects when compared with groups receiving bupivacaine or tramadol alone.…”

Section: Discussionmentioning

confidence: 99%

The Analgesic Effects of Morphine and Tramadol Added to Intra-articular Levobupivacaine-Tenoxicam Combination for Arthroscopic Knee Surgery on Postoperative Pain; a Randomized Clinical Trial

Oral¹,

Hanci²,

Sivrikaya

et al. 2015

Anesth Pain Med

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Background:Arthroscopic knee surgery is commonly performed as an outpatient procedure and is often associated with postoperative pain.Objectives:We aimed to compare the effects of intra-articular levobupivacaine-tenoxicam-tramadol and levobupivacaine-tenoxicam-morphine combinations on postoperative pain in patients undergoing elective arthroscopic knee surgery.Materials and Methods:A total of 90 ASA I-II patients undergoing elective arthroscopic meniscectomy under general anesthesia were enrolled. The participants were randomly allocated to three groups to receive the following intra-articular medications after completion of the surgery and before deflation of the tourniquet: Group S, 20 mL of saline; Group T, 35 mg of levobupivacaine, 20 mg of tenoxicam, and 100 mg of tramadol in 20 mL saline; and Group M, 35 mg of levobupivacaine, 20 mg of tenoxicam, and 4 mg of morphine in 20 mL saline. Visual analogue scale values at rest (VASr) and at active flexion of knee (VASa) at postoperation hours 1, 2, 4, 8, 12, and 24, duration of analgesia, total analgesic consumption, and number of rescue analgesia at 24 hours were evaluated.Results:VASr and VASa were significantly higher in group S in comparison to other groups (P < 0.05). Duration of analgesia was significantly longer in Group T and Group M than in Group S (P < 0.05). The difference between group T and group M was also significant (P < 0.05). Number of rescue analgesia and total analgesic consumption at postoperative hour 24 was significantly fewer in group M compared with other groups (P < 0.05).Conclusions:Intra-articular levobupivacaine-tenoxicam-morphine combination provides effective pain relief, longer analgesic duration, and less analgesic requirement when compared with intra-articular levobupivacaine-tenoxicam-tramadol combination and saline after knee arthroscopic surgery.

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Preemptive intraarticular tramadol for pain control after arthroscopic knee surgery

Cited by 12 publications

References 20 publications

Comparative study in patients with symptomatic internal derangements of the temporomandibular joint: analgesic outcomes of arthrocentesis with or without intra-articular morphine and tramadol

Comparative study in patients with symptomatic internal derangements of the temporomandibular joint: analgesic outcomes of arthrocentesis with or without intra-articular morphine and tramadol

Tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy: a systematic review and meta‐analysis

The Analgesic Effects of Morphine and Tramadol Added to Intra-articular Levobupivacaine-Tenoxicam Combination for Arthroscopic Knee Surgery on Postoperative Pain; a Randomized Clinical Trial

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