Preemptive hemodynamic intervention restricting the administration of fluids attenuates lung edema progression in oleic acid-induced lung injury

Cano, Anselmo Gil; Romero, Manuel Gracia; García, Manuel Ignacio Monge; González, Pedro Guijo; Campos, Jackie

doi:10.1016/j.medine.2016.08.004

Cited by 1 publication

(2 citation statements)

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“…Under such circumstances, the occurrence and development of ARDS are not only related to the primary lung injury; a more common cause of ARDS development may be the “second hit” caused by inappropriate interventions based on inappropriate understanding. [ 5 ] Despite significant progress in our understanding of ARDS, its morbidity and mortality remain high. [ 1 ] In view of the limited effective treatments for ARDS, the strategic focus of ARDS has shifted to identifying potential or high-risk ARDS patients at early stages of the disease and implementing treatment strategies aimed at reducing ARDS and related organ failure.…”

Section: Introductionmentioning

confidence: 99%

“…It can then progress rapidly to severe ARDS and is often difficult to treat. Under such circumstances, the occurrence and development of ARDS are not only related to the primary lung injury; a more common cause of ARDS development may be the “second hit” caused by inappropriate interventions based on inappropriate understanding [5] . Despite significant progress in our understanding of ARDS, its morbidity and mortality remain high [1] .…”

Section: Introductionmentioning

confidence: 99%

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Acute respiratory distress syndrome: focusing on secondary injury

Pan¹,

Liu

et al. 2021

Chinese Medical Journal

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Acute respiratory distress syndrome (ARDS) is one of the most common severe diseases seen in the clinical setting. With the continuous exploration of ARDS in recent decades, the understanding of ARDS has improved. ARDS is not a simple lung disease but a clinical syndrome with various etiologies and pathophysiological changes. However, in the intensive care unit, ARDS often occurs a few days after primary lung injury or after a few days of treatment for other severe extrapulmonary diseases. Under such conditions, ARDS often progresses rapidly to severe ARDS and is difficult to treat. The occurrence and development of ARDS in these circumstances are thus not related to primary lung injury; the real cause of ARDS may be the “second hit” caused by inappropriate treatment. In view of the limited effective treatments for ARDS, the strategic focus has shifted to identifying potential or high-risk ARDS patients during the early stages of the disease and implementing treatment strategies aimed at reducing ARDS and related organ failure. Future research should focus on the prevention of ARDS.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%