Preemptive analgesia of metamizole versus ibuprofen in retinal laser photocoagulation

Santo, Artur M.D.; Auge, Renato Maluf; Ferraz, Caroline Amaral

doi:10.5935/0034-7280.20160003

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…Acute procedural pain is still a neglected phenomenon in health care (Cakmak et al, 2017;Lee, 2016;Song et al, 2018), particularly in ophthalmic procedures (Araújo et al, 2015;Castro et al, 2014;Chen et al, 2012;Chiu & Wu, 2011;Quigley et al, 2019;Ramezani et al, 2017;Santo et al, 2016). These findings corroborate our results, since most of the patients who underwent argon LRP reported pain, despite the anesthetic used, which demonstrates the nociceptive nature of the procedure.…”

Section: Discussionsupporting

confidence: 87%

“…As well as several ECRs that evaluated the pain during LRP in patients with diabetic retinopathy, our study standardized the technique of LRP, since it is unrealistic to provide number of shots with the same value for all patients undergoing LRP. In this sense, a study analyzed whether the power of the shots could influence the presence of severe pain and concluded that there is no significant difference in pain intensity (Santo et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…Laser retinal photocoagulation (LRP) is considered the first-choice treatment for diabetic retinopathy (Evans, Michelessi, & Virgili, 2014;Song et al, 2018;Wadhwani et al, 2019). However, pain during treatment can lead to reduced therapeutic efficacy due to higher rates of abandonment of treatment, increasing the risks of visual loss (Inan et al, 2016;Quigley et al, 2019;Santo, Auge, & Ferraz, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Randomized clinical trials have investigated the pharmacological management of LRP-related pain (Araújo et al, 2015;Pirelli et al, 2019;Ramezani et al, 2017;Santo et al, 2016). However, there is still little evidence to recommend the best non-pharmacological management practices for pain associated with LRP (Ribeiro, Ribeiro, Pinto, & Ribeiro, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Efeito analgésico da música durante a fotocoagulação retinal a laser em diabéticos: Um estudo cruzado, randomizado e controlado por placebo

Ribeiro¹,

Ribeiro²,

Oliveira³

et al. 2021

RSD

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Objetivo: Avaliar prospectivamente o efeito analgésico da música de preferência do paciente com retinopatia diabética que foram submetidos à fotocoagaluação retiniana a laser (FRL). Metodologia: Trata-se de um ensaio clínico controlado, randomizado, cego e crossover de dois períodos. Participaram vinte pacientes (40 olhos) com retinopatia diabética proliferativa que foram submetidos à FRL. A escuta musical de preferência do paciente antes e durante a FRL foi a intervenção não farmacológica testada. O grupo controle (GC) foi composto por pacientes que receberam apenas o tratamento farmacológico padrão e o grupo experimental (GE) por aqueles que receberam a intervenção associada ao tratamento farmacológico padrão. A dor foi mensurada pela Escala Numérica Verbal. As diferenças dos escores de dor foram examinadas por meio dos testes Aligned Rank Transformed ANOVA, Mann-Whitney U e de Wilcoxon. O tamanho do efeito das diferenças foi avaliado usando Tamanhos de Efeito Rank Bisserial e Parcial Square. Resultados: Os participantes eram predominantemente do sexo masculino (60%), adultos (57,4±9,1 anos), com comorbidades (65%), com deficiência visual ≥ 1 ano (65%). Os participantes que ouviram música apresentaram menores escores de dor (GE: 4,80±2,46) comparados aos que não ouviram (GC:6,75±1,59; p=0,013). A aplicação de música de preferência do paciente mostrou um grande tamanho do efeito analgésico (η²=0,189). Conclusão: Ouvir música de preferência do paciente, associada à analgesia padrão, é eficaz no alívio da dor aguda relacionada à FRL e deve ser incorporada à prática clínica para o tratamento multimodal da dor nesse procedimento.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efeito analgésico da música durante a fotocoagulação retinal a laser em diabéticos: Um estudo cruzado, randomizado e controlado por placebo

Ribeiro¹,

Ribeiro²,

Oliveira³

et al. 2021

RSD

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Pain Management Strategies before Pan‐Retinal Photocoagulation for Diabetic Retinopathy: A Systematic Review

Johari,

Moallem,

Amini

et al. 2024

Journal of Ophthalmology

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Purpose. This systematic review aims to consolidate key findings regarding the efficacy of pain relief medications administered prior to pan‐retinal photocoagulation (PRP) for diabetic retinopathy (DR). Methods. A comprehensive search of major databases from 1993 to 2023 was conducted. Clinical trials comparing pain relief drugs before PRP in patients diagnosed with DR requiring PRP treatment were eligible for inclusion. The assessment of pain scores involved the use of various scales, such as the visual analog scale (VAS), numerical rating scale (NRS), verbal rating scale (VRS), and other ordinal pain scales. In addition, laser parameters were taken into consideration during the analysis. Results. Twenty‐two clinical trials from initial 150 studies were included in the review. Nine studies evaluated the pain relief effects of nonsteroidal anti‐inflammatories NSAIDs (selective NSAID and nonselective NSAID), two studies compared the effects of opioids (conventional opioids and atypical opioids), and eleven studies investigated the effects of benzodiazepines, lidocaine, and other sedatives. Conclusion. This review synthesizes findings from multiple studies reporting pain as an adverse outcome of PRP in patients with advanced DR. Based on the evidence from reviewed clinical trials, the administration of lidocaine 2% via transconjunctival, retrobulbar, or peribulbar block along with specific NSAIDs, such as topical ketorolac administrated 24 hours before treatment or oral diclofenac potassium (50 mg) prior to PRP, demonstrated beneficial effects among patients with DR.

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Preemptive analgesia of metamizole versus ibuprofen in retinal laser photocoagulation

Cited by 2 publications

References 15 publications

Efeito analgésico da música durante a fotocoagulação retinal a laser em diabéticos: Um estudo cruzado, randomizado e controlado por placebo

Efeito analgésico da música durante a fotocoagulação retinal a laser em diabéticos: Um estudo cruzado, randomizado e controlado por placebo

Pain Management Strategies before Pan‐Retinal Photocoagulation for Diabetic Retinopathy: A Systematic Review

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