Preeclampsia into eclampsia: Toward a new paradigm

Maternal and perinatal outcome of eclampsia in a tertiary care centre

“…Pathogenesis of postpartum eclampsia is less understood. 9 Ecalmpsia was seen in 49% of patients at term gestation in our study which is similar to a study done by Khanum M et al i.e. 53% at term gestation and 43% at near term gestation.…”

Ophthalmic Artery-Resistive Index and Evidence of Overperfusion-Related Encephalopathy in Severe Preeclampsia

“…Headache and visual symptoms, the main clinical manifestations of PRES, composed the best indicators of the risk of seizures in PEES. 4,15,16 In our study, headache and visual symptoms were carefully characterized. The comprehensive ophthalmoscopic examination performed in our study excluded retinal findings related to PEES and avoided significant bias in the characterization of clinical evidence of PRES.…”

“…[11][12][13][14][15][16] Neurological involvement compatible with PRES is a major feature in the clinical spectrum of preeclampsia. [1][2][3][4]6 On the other hand, PEES is a well-established cause of PRES.…”

“…[13][14] In a large epidemiological study, significant hypertension and proteinuria were absent in 38% of patients who developed seizures. 14 Further, a significant number of patients present seizures as the first manifestation of PEES 15 or during adequate monitoring in the hospital. 14 On the other hand, studies have reported lower ophthalmic artery resistance in patients with severe preeclampsia, especially those with headache and visual symptoms.…”

“…4,5 Most clinical and laboratory parameters of PEES are inaccurate predictors of PRES. [11][12][13][14][15][16] In addition, PRES often develops despite adequate medical monitoring. [13][14] In a large epidemiological study, significant hypertension and proteinuria were absent in 38% of patients who developed seizures.…”