1997
DOI: 10.1097/00005072-199709000-00009
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Predominant Localization of the LIS Family of Gene Products to Cajal-Retzius Cells and Ventricular Neuroepithelium in the Developing Human Cortex

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Cited by 55 publications
(25 citation statements)
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“…This was not the case, because we observed a differential, highly selective elimination of a subpopulation of C-R cells. The identification of several subpopulations of layer I cells with selective persistence in primates may help in elucidating their possible role in congenital malformations of the human cerebral cortex such as lissencephaly (Clark et al, 1997;Hong et al, 2000).…”
Section: Function and Fatementioning
confidence: 99%
See 1 more Smart Citation
“…This was not the case, because we observed a differential, highly selective elimination of a subpopulation of C-R cells. The identification of several subpopulations of layer I cells with selective persistence in primates may help in elucidating their possible role in congenital malformations of the human cerebral cortex such as lissencephaly (Clark et al, 1997;Hong et al, 2000).…”
Section: Function and Fatementioning
confidence: 99%
“…Although these cells have continued to fascinate investigators, a recent discovery that they produce reelin, a glycoprotein essential for orderly neuronal cell migration and ingrowth of afferents into the cerebral cortex, has augmented this attention (D'Arcangelo et al, 1995(D'Arcangelo et al, , 1997Ogawa et al, 1995;Del Rio et al, 1997;Nakajima et al, 1997;Curran and D'Arcangelo, 1998). It was also suggested that C-R cells may be involved in developmental disorders of the cerebral cortex in humans (Rakic and Caviness, 1995;Clark et al, 1997;Impagnatiello et al, 1998;Hong et al, 2000).…”
mentioning
confidence: 99%
“…Cajal-Retzius cells also have an important role during normal cortical development. Their impairment is related to developmental disorders of the human cerebral cortex with disturbed neural migration, resulting in lissencephaly and mental retardation (Rakic and Caviness, 1995;Clark et al, 1997;Hong et al, 2000). Additional roles for Cajal-Retzius cells, such as in schizophrenia (Impagnatiello et al, 1998), or in repair of brain lesions (Super et al, 1997) have been suggested.…”
Section: Introductionmentioning
confidence: 99%
“…5,6 This gene encodes the ␤ subunit of brain type platelet-activating factor acetylhydrolase (PAFAH1B1), 7 which is present in abundance in normal brains but is deficient in those of patients with MDS. 8,9 On the other hand, ILS consists of heterogeneous conditions. Approximately 40% of sporadic ILS patients have a deletion of 17p13.3 involving the LIS1 gene.…”
mentioning
confidence: 99%