Predominance of Methicillin-Resistant
            <i>Staphylococcus aureus</i>
            among Pathogens Causing Skin and Soft Tissue Infections in a Large Urban Jail: Risk Factors and Recurrence Rates

David, Michael Z.; Mennella, Connie; Mansour, M.M.; Boyle-Vavra, Susan; Daum, Robert S.

doi:10.1128/jcm.01423-08

Cited by 71 publications

(64 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The limited number of reports published, however, focused primarily on MRSA, followed by Mycobacteria tuberculosis and Chlamydia (4,12,13,(40)(41)(42)62). In this report, the antimicrobial susceptibility of 123 CCF Acinetobacter isolates against 18 antibiotics was determined, followed by a series of experiments to elucidate the mechanisms of resistance in FQs, aminoglycosides, and tigecycline in these CCF isolates.…”

Section: Discussionmentioning

confidence: 99%

“…being frequently isolated from inmates in California state prisons (California correctional facilities, or CCFs). Although a few published reports describing prison outbreaks exist, such reports focused primarily on methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis clinical isolates obtained from correctional facilities in the United States (4,12,41). Currently, there is a lack of published studies focusing on the prevalence of multidrug resistance, dissemination patterns, and mechanisms of antibiotic resistance of Acinetobacter clinical isolates from correctional facilities.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Phenotypic and Molecular Characterization of Acinetobacter Clinical Isolates Obtained from Inmates of California Correctional Facilities

et al. 2011

View full text Add to dashboard Cite

Acinetobacter spp. increasingly have been wreaking havoc in hospitals and communities worldwide. Although much has been reported regarding Acinetobacter isolates responsible for nosocomial infections, little is known about these organisms in correctional facilities. In this study, we performed species identification, examined the antibiotic resistance profiles, and determined the mechanisms of resistance and clonal relationships of 123 Acinetobacter isolates obtained from inmates of 20 California correctional facilities (CCFs). We found that 57.7% of the isolates belong to A. baumannii, followed by isolates of Acinetobacter genomic species 3 (gen. sp. 3; 23.6%) and of Acinetobacter gen. sp. 13TU (10.6%). Multidrug-resistant (MDR) CCF isolates were found in only six CCFs. Additionally, DNA sequences of gyrA and parC genes were consistent with fluoroquinolone (FQ) susceptibility phenotypes. Furthermore, the presence of class 1 integrons was detected in 15 CCF isolates, all of which are MDR. Integron-associated gene cassettes encode several aminoglycoside modification enzymes, which correlate with most of the aminoglycoside-resistant phenotypes. Antimicrobial susceptibility testing in the presence of Phe-Arg-␤-naphthylamide dihydrochloride and 1-(1-naphthylmethyl)-piperazine indicated the involvement of efflux pumps in the FQ resistance of only a few CCF isolates. Finally, genetic profiling showed that there was no evidence of A. baumannii outbreaks in CCFs. Instead, our analyses revealed only limited clonal dissemination of mostly non-MDR A. baumannii strains in a few facilities. This study represents the first report to characterize phenotypic and molecular features of Acinetobacter isolates in correctional facilities, which provides a baseline for monitoring the antimicrobial resistance changes and dissemination patterns of these organisms in such specialized institutions.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Phenotypic and Molecular Characterization of Acinetobacter Clinical Isolates Obtained from Inmates of California Correctional Facilities

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Compared to HA-MRSA, CA-MRSA also seems to possess different risk factors for acquisition, as it has been most often reported in populations of intravenous drug users, men who have sex with men, prison inmates, contact sport teams, military recruits and children (80,95,96,97,98,99,100,101).…”

Section: Mrsa: Methicillin-resistant S Aureusmentioning

confidence: 99%

Methicillin-resistantStaphylococcus aureus(MRSA) in food production animals

et al. 2010

View full text Add to dashboard Cite

SummaryUntil recently, reports on MRSA in livestock were mainly limited to occasional detections in dairy cattle mastitis. Since 2005 however, studies show the existence of an MRSA clone, CC398, which has been reported colonizing pigs, veal calves and broiler chickens and infecting dairy cows. Many aspects of its prevalence in pigs are not yet understood. In other livestock, colonizing capacity and reservoir status are still unclear.. MRSA CC398 has also been detected in meat but, like for other MRSA, the risk this might pose is rather unclear. For now, the most worrying aspect of MRSA CC398 seems to be its capacity to spread to humans. This might complicate MRSA control measures in human healthcare, posing for urgent research into risk factors and transmission routes. Overall, infections with MRSA CC398 are much less reported than carriage. More investigation into its pathogenic potential is though required. Also the origin and evolution of this clone remain to be revealed.3

show abstract

“…Due to the high volume of isolates at CHO (three times the number as UCSF and SFGH combined), one third were randomly selected for chart abstraction. Multiple S aureus isolates from a subject were considered part of the same episode if collected within 1 month of the first isolate [21]. Episodes were included if the following CDC clinical criteria for CA-MRSA were met: did not live in a long-term care facility in the past year, no hospitalization in the past year, no dialysis or surgery in the past year, and no presence of indwelling catheter or other percutaneous device [22].…”

Section: Data Collectionmentioning

confidence: 99%

Epidemiologic Similarities in Pediatric Community-Associated Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus in the San Francisco Bay Area

Hsiang

Shiau

Nadle³

et al. 2012

Journal of the Pediatric Infectious Diseases Society

View full text Add to dashboard Cite

Predominance of Methicillin-Resistant Staphylococcus aureus among Pathogens Causing Skin and Soft Tissue Infections in a Large Urban Jail: Risk Factors and Recurrence Rates

Cited by 71 publications

References 22 publications

Phenotypic and Molecular Characterization of Acinetobacter Clinical Isolates Obtained from Inmates of California Correctional Facilities

Phenotypic and Molecular Characterization of Acinetobacter Clinical Isolates Obtained from Inmates of California Correctional Facilities

Methicillin-resistantStaphylococcus aureus(MRSA) in food production animals

Epidemiologic Similarities in Pediatric Community-Associated Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus in the San Francisco Bay Area

Contact Info

Product

Resources

About