Predisposition for atopy and pulmonary prognosis at preschool age of patients diagnosed with respiratory distress in the neonatal period

Abstract

Aim: In this study, we aimed to determine the predisposition for atopy and pulmonary functions of patients who were followed up for respiratory distress syndrome in the neonatal period. Material and Methods: Fifty children hospitalized with respiratory distress in the neonatal period were included in the study, and the control group included 31 children, who had no respiratory problems, were included as the control group. Pulmonary function test was performed to evaluate the lung functions of the children included in the study. A Chest x-ray was performed. Total IgE and phadiaotope were studied in serum samples. A Skin prick test was done. Results: Serum total IgE results in the patient group were statistically significantly higher than in the control group (p=0.02). Of the 50 patients in the patient group, 5 (10%) had atopic asthma, 4 (8%) had nonatopic asthma, 2 (4%) had bronchopulmonary dysplasia, 2 (4%) had atopic dermatitis and 2 (4%) had allergic rhinitis. When 50 patients were examined in terms of atopy, 10 (20%) were considered atopic. In the control group, 1 child (3.2%) was considered atopic. Atopy was found to be statistically significantly higher in the patient group (p=0.03). Although the FVC, FEV1, FEV1/FVC and PEF values measured in the patient group were lower than those in the control group, the results were not statistically significant. Discussion: Diagnoses of atopic disease (atopic asthma, allergic rhinitis, atopic dermatitis), non-atopic asthma and bronchopulmonary dysplasia were found to be higher in patients followed up for respiratory distress in the neonatal period compared to the control group without respiratory problems.