Predisposing Factors in Sudden Cardiac Death in Tecumseh, Michigan

Chiang, Benjamin N.; Perlman, Lawrence V.; Fulton, Mary; Ostrander, Leon D.; Epstein, Frederick H.

doi:10.1161/01.cir.41.1.31

Cited by 153 publications

(31 citation statements)

References 21 publications

(3 reference statements)

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“…It should be stressed that the application of this correction may possibly result in an unduly concervative result; some authors find this correction altogether unnecessary (9,22). Our observations seem to confirm the data of Chiang et al (2) who found in their Tecumseh study, a higher increase in sudden-death rate among subjects with VPB although in a later article a less definite conclusion was expressed (3). On the other hand, Fisher and Tyroler (6) did not find any significant increase in sudden death in patients with VPB.…”

Section: Discussionsupporting

confidence: 90%

Relationship between Ventricular Arrhythmias Detected by Ambulatory ECG Monitoring and Subsequent Sudden Cardiac Death

Stern¹,

Tzivoni²,

Keren³

et al. 1981

Cardiology

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During the years 1971-1974, ambulatory ECG monitoring (AEM) during everyday activities was done in 888 consecutive subjects. Half of them were patients who suffered from chronic ischemic heart disease (IHD), while in the others no symptoms or signs of this disease were found. Ventricular arrhythmias (VA) were detected in 196 subjects of the former and in 190 of the latter group. The Bureau of Statistics provided information concerning the individuals who died before December 31, 1976, the cause of their death and whether or not the death occurred in hospital or was ‘sudden’.We found that during the follow-up period, the rate of sudden cardiac death among the patients with IHD in whom AEM detected VA was higher than in subjects without VA. In the former group, there were 12 sudden cardiac deaths among 196 patients, while in the latter there were only 4 out of 248, a statistically significant difference. Sudden cardiac death was more frequent in individuals without IHD if AEM disclosed VA (4 sudden cardiac deaths among 190 subjects), as compared to individuals without VA (no sudden cardiac deaths among 254 subjects).

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Section: Discussionsupporting

confidence: 90%

Relationship between Ventricular Arrhythmias Detected by Ambulatory ECG Monitoring and Subsequent Sudden Cardiac Death

Stern¹,

Tzivoni²,

Keren³

et al. 1981

Cardiology

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“…Some studies have implicated over weight as a risk factor for sudden death [1,12,21], some studies have found no causal relationship [5,13].…”

Section: Resultsmentioning

confidence: 99%

Sudden Death and Physical Activity

Vuori¹,

Mäkaräinen²,

Jäskeläinen³

1978

Cardiology

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The circumstances surrounding 2,606 sudden deaths were studied by reviewing the death certificates and autopsy reports to establish correlations with the type and intensity of physical activity preceding death. 73% of the deaths were caused by acute or chronic ischemic heart disease. Physical activity was more commonly associated with death in men than in women and in subjects under 50 years of age than in older people. Instantaneous cardiac death was observed only with coexisting activity. There was no relationship between the intensity of the effort and the number of cardiac deaths. Sudden deaths in connection with sporting activities were rare. There were, however, 67 nonaccidental deaths during or following sauna bath. In the second part of the study, 10 sudden deaths are described in connection with day-long ski hikes. Strenuous physical exercise seems to have played an important role in these cases. However, most of the subjects had serious cardiovascular risk factors which were known in advance or could have been identified by medical examination. In conclusion, daily physical activities or sports cannot be incriminated as an important contributory factor in sudden death in the general population. However, there is a risk of cardiac complications in connection with strenuous physical exercise in subjects with manifest or latent cardiac disease.

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“…The clinical significance of asystole for 20 s or more in a young and healthy child is not known. Ventricular fibrillation has been reported in older patients with atrioventricular block and severe bradycardia (22,23). Treatment of severe BHS with a permanent backup pacemaker was reported by Villain et al (24) in a series of 11 patients, in whom prolonged sinus node suppression was documented.…”

Section: Figure 1) a Rhythm Strip From An Event Recorder At The Time mentioning

confidence: 93%

A pacemaker for asystole in breath-holding spells

Legge

Kantoch

Seshia

et al. 2002

Paediatrics &Amp; Child Health

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Two cases of young children with frequent severe breath-holding spells complicated by prolonged asystole and seizures are reported. A ventricular pacemaker was implanted in each child, and both have subsequently remained free of syncope, although they continue to exhibit breath-holding behaviour.Key Words: Asystole; Breath-holding; Pacemaker; Syncope Un stimulateur en cas d'asystolie dans les spasmes du sanglotOn rend compte du cas de deux jeunes enfants présentant des spasmes du sanglot fréquents et graves, compliqués par une asystolie prolongée et des convulsions. Un stimulateur ventriculaire a été implanté chez chaque enfant, et si tous deux ont continué à faire des spasmes du sanglot, ils n'ont plus fait de syncopes. B reath-holding spells (BHS) are common in early childhood, typically occurring between the ages of six months and four years. Severe pallid spells and, less commonly, cyanotic spells may be complicated by the loss of consciousness, posturing and generalized seizures. A toddler and an infant who experienced prolonged asystole at the time of severe BHS and who were treated with the implantation of ventricular pacemakers are described. CASE 1 PRESENTATIONAn 18-month-old "determined and busy" girl was referred to the cardiology clinic with a history of syncope since the age of 11 months. All events were precipitated by the child being upset, usually when something was taken away from her without warning or when she experienced a minor injury. The child would cry hard; become cyanotic; stop breathing on expiration; turn silent, pale and limp; and lose consciousness. She would recover with an inspiratory gasp within a few minutes. The parents documented 49 BHS. On four occasions, the child developed opisthotonic posturing and myoclonic jerks. Twice the pupils became dilated and she became incontinent. Her tone and skin colour improved gradually over several minutes. Spells were followed by at least one-and-a-half hours of sleep. When the parents learned about asystole associated with breath-holding, they treated the individual episodes with oxygen, res-

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Predisposing Factors in Sudden Cardiac Death in Tecumseh, Michigan

Cited by 153 publications

References 21 publications

Relationship between Ventricular Arrhythmias Detected by Ambulatory ECG Monitoring and Subsequent Sudden Cardiac Death

Relationship between Ventricular Arrhythmias Detected by Ambulatory ECG Monitoring and Subsequent Sudden Cardiac Death

Sudden Death and Physical Activity

A pacemaker for asystole in breath-holding spells

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