Predictors of Visual outcome in Post Fever Retinitis: A Retrospective Analysis

Abstract

Purpose: To identify the predictors of final visual outcome in cases with post fever retinitis (PFR).Methods : This is a retrospective study of cases with diagnosis of post fever retinitis. Color fundus photograph and optical coherence tomography (OCT) parameters at presentation and final visit were analysed. Various factors at presentation [age, systemic illness, best corrected visual acuity (BCVA), area of retinitis and hard exudates, OCT parameters], at final visit (optic disc pallor, OCT parameters) and the treatment modalities used were correlated with BCVA at final visit.Results : Twenty four eyes of 16 patients with PFR were included in the study. Median BCVA at presentation was 6/60 and at final visit was 6/9. By multiple linear regression after adjusting for other variables, for every 1 unit increase in height of SRF at fovea at presentation, the value of final BCVA decreased by 0.001 unit. For every 1 unit increase in extent of EZ loss and subfoveal deposit height, the value of final BCVA decreased by 0.0001unit and 0.004 unit respectively.Conclusion: Height of SRF at presentation, extent of EZ loss and subfoveal deposit height at final visit were associated with poor final BCVA in PFR.

Epidemic retinitis - Factors associated with poor visual outcomes

“…The OCT parameters predicting visual outcomes in ER have been very recently reported by Biswal et al . [ 7 ] As in their study, we also found subfoveal deposits and optic disc pallor responsible for poor visual outcomes. In addition to those factors, they have also found the height of subretinal fluid at presentation as one of the contributory factors.…”

“…As demonstrated in Group B despite high CMT and retinitis lesion within 1500 μm of the foveal center, the eyes had better visual outcomes. Biswal et al .’s[ 7 ] study found no statistically significant correlation between age, systemic illness, the interval between fever and retinitis, area of retinitis, different treatment modalities, and the final visual gain. This is in contrast with our findings that older age, diabetic status, and delayed ophthalmic checkups had a significant correlation with the final visual outcome.…”

“…In a recently published series of 16 patients, certain optical coherence tomography (OCT) scan biomarkers were predicted to be responsible for poor visual outcomes. [ 7 ] Macular involvement in ER is common and as expected is directly associated with visual outcomes. Comprehensive comparative systematic evaluation of causes for unsatisfactory treatment outcomes in a larger series has not been reported in any studies on ER.…”