Predictors of variability in urinary incontinence and overactive bladder symptoms

Stewart, Walter F.; Minassian, Vatché A.; Hirsch, Annemarie G.; Kolodner, Kenneth B.; FitzGerald, MaryPat; Burgio, Kathryn L.; Cundiff, Geoffrey W.; Blaivas, Jerry; Newman, Diane K.; Lerch, Virginia; Dilley, Anne

doi:10.1002/nau.20753

Cited by 20 publications

(18 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These were also associated factors or predictors in this study. However, some other predictors such as duration of UI, which was the most important according to the final model of multivariate regression, were characterized in only some of the studies found (20)(21) . Diabetes mellitus was also one of the most important factors in the occurrence of UI, which is also confirmed in other studies (22)(23) .…”

Section: Resultsmentioning

confidence: 99%

Prevalence of Urinary Incontinence in a Random Sample of the Urban Population of Pouso Alegre, Minas Gerais, Brazil

Santos

2010

Rev. Latino-Am. Enfermagem

View full text Add to dashboard Cite

This study determines and analyzes the prevalence of Urinary Incontinence (UI) and its demographic and clinical predictors. This epidemiological and cross-sectional study was approved by the Research Ethics Committee of the University of São Paulo, Nursing School.The sample was randomly selected by cluster technique and included 519 individuals aged ≥18 years, living in 341 houses in urban areas. Data were analyzed through Chi-Square, Hosmer Lemeshow's test and multivariate logistic regression (stepwise). Prevalence rates were standardized by gender and age. Of the 519 people composing the sample: 20.1% had UI, 32.9% were women and 6.2% were men. Longer duration of losses (OR = 29.3; p<0.001), diabetes mellitus (OR = 17.7; p<0.001), stroke (OR = 15.9; p<0.001), and cystocele (OR = 12.5; p <0.001) were the factors most strongly associated with UI. This study enabled the identification of UI epidemiology and can contribute to the development of public policies for its primary and secondary prevention and treatment, even if such measures are initially implemented at the city level. Descritores: Incontinência Urinária; Epidemiologia; Enfermagem. Prevalencia de la incontinencia urinaria en muestra aleatoria de la población urbana de Pouso Alegre, Minas Gerais, BrasilEl estudio tiene por objetivo conocer la prevalencia de la incontinencia urinaria (IU), de los factores de predicción demográficos y clínicos de la presencia de IU. Se trata de un estudio epidemiológico de corte transversal, aprobado por el Comité de Ética de la Escuela de Enfermería de la Universidad de Sao Paulo. Muestreo estratificado por conglomerado compuesto de 519 individuos con edad ≥18 años, residentes en 341 domicilios del área urbana, sorteados aleatoriamente. Las pruebas utilizadas fueron Chi-cuadrado, HosmerLemeshow y regresión logística multivariante (stepwise). Las prevalencias de IU fueron estandarizadas por sexo y edad, en una muestra de 519 personas, siendo 20,1 % en la población general -32,9% eran mujeres y 6,2% hombres. Los factores más fuertemente asociados a la IU fueron: mayor tiempo de pérdidas (OR=29,3; p<0,001), diabetes mellitus (OR=17,7; p<0,001), accidente vascular encefálico (OR=15,9; p<0,001) y cistocele (OR=12,5; p<0,001). El estudio permitió conocer la epidemiologia de la IU y puede contribuir para el desarrollo de políticas públicas para su prevención primaria y secundaria, su tratamiento, inclusive considerando su inicio en el ámbito municipal.

show abstract

Section: Resultsmentioning

confidence: 99%

Prevalence of Urinary Incontinence in a Random Sample of the Urban Population of Pouso Alegre, Minas Gerais, Brazil

Santos

2010

Rev. Latino-Am. Enfermagem

View full text Add to dashboard Cite

show abstract

“…Previous cross-sectional studies have reported differences in symptom severity, quality of life, and bother by UI subtype [4,[11][12][13][14][15][21][22][23][24][25]. Some studies found that mixed and urgency UI vs stress UI had a significantly higher impact on quality of life [4,[11][12][13].…”

Section: Discussionmentioning

confidence: 99%

“…The original study is described in detail elsewhere [15,16]. In the following section, we summarize the source population, the study cohort, the Bladder Health Survey (BHS), the electronic health records (EHR), and the analysis used.…”

Section: Methodsmentioning

confidence: 99%

“…Composite scores were derived for each of the two UI subtypes with a range of 0 to 6 [16]. The BHS questions on UI and its subtypes [15,16] were derived from previously validated questionnaires [5,[17][18][19]. The questionnaire was assessed for content validity by clinical experts and was clinically validated in a population sample [17] and from several other questions where either clinical or urodynamic validation studies had previously been carried out [5,20].…”

Section: Bladder Health Surveymentioning

confidence: 99%

See 1 more Smart Citation

The interaction of stress and urgency urinary incontinence and its effect on quality of life

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Abstract Bladder dysfunction is common in the general population (Stewart et al 2010) and even more so among patients seeing a physician for any reason (Goepel et al 2002). It often manifests as lower urinary tract symptoms (LUTS), a term originally coined to describe voiding and storage symptoms in men with benign prostatic hyperplasia (BPH) but now more universally used to describe any type of voiding and storage symptoms in both sexes.…”

mentioning

confidence: 99%

Are blood vessels a target to treat lower urinary tract dysfunction?

Michel

Chess-Williams

Hegde

2015

Naunyn-Schmiedeberg's Arch Pharmacol

View full text Add to dashboard Cite

Bladder dysfunction is common in the general population (Stewart et al. 2010) and even more so among patients seeing a physician for any reason (Goepel et al. 2002). It often manifests as lower urinary tract symptoms (LUTS), a term originally coined to describe voiding and storage symptoms in men with benign prostatic hyperplasia (BPH) but now more universally used to describe any type of voiding and storage symptoms in both sexes. Studies into possible causes of urinary bladder dysfunction have long focused on detrusor smooth muscle cells (Turner and Brading 1999). More recently, it became clear that several other types of cells and organs contribute to regulating detrusor smooth muscle function. These include the urothelium (Andersson and McCloskey 2014; Michel 2015), afferent nerves (Michel and Igawa 2015; Yoshimura et al. 2014b), and the central and autonomic nervous systems (Fowler and Griffiths 2010; Yoshimura et al. 2014a). Alterations in any of these may at least partly be responsible for detrusor dysfunction and, accordingly, be potential targets for the treatment of bladder dysfunction. As highlighted by an article in this issue of Naunyn-Schmiedeberg's Archives of Pharmacology (Bayrak et al. 2015), there is an additional suspect, the bladder vasculature. This article will discuss the currently available experimental and clinical evidence for a role of the vasculature in causing bladder dysfunction, and how existing and emerging treatments may modulate bladder function by acting on blood vessels. Due to a similarity in concept, data on prostate perfusion will also be discussed to some extent.

show abstract

Predictors of variability in urinary incontinence and overactive bladder symptoms

Abstract: Inter-individual and intra-individual occurrences of urgency and UI symptoms are highly variable in the general population. Use of established predictors to select individuals with less variability in symptoms may help to reduce placebo rates in clinical trials.

Cited by 20 publications

References 29 publications

Prevalence of Urinary Incontinence in a Random Sample of the Urban Population of Pouso Alegre, Minas Gerais, Brazil

Prevalence of Urinary Incontinence in a Random Sample of the Urban Population of Pouso Alegre, Minas Gerais, Brazil

The interaction of stress and urgency urinary incontinence and its effect on quality of life

Are blood vessels a target to treat lower urinary tract dysfunction?

Contact Info

Product

Resources

About