Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging

Hudson, Amanda; Montelpare, William

doi:10.3390/ijerph18158054

Cited by 154 publications

(147 citation statements)

References 54 publications

(114 reference statements)

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“…Prior COVID diagnosis was also associated with vaccine hesitancy, potentially reflecting HCWs' preference for physiological immunity. Finally, as in other studies [29][30][31], one's family size was predictive of vaccine hesitancy. This finding can be explained through interrelated factors, including socioeconomic status.…”

Section: Discussionsupporting

confidence: 72%

Predictors of COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Southern California: Not Just “Anti” vs. “Pro” Vaccine

et al. 2021

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In this study, we evaluated the status of and attitudes toward COVID-19 vaccination of healthcare workers in two major hospital systems (academic and private) in Southern California. Responses were collected via an anonymous and voluntary survey from a total of 2491 participants, including nurses, physicians, other allied health professionals, and administrators. Among the 2491 participants that had been offered the vaccine at the time of the study, 2103 (84%) were vaccinated. The bulk of the participants were middle-aged college-educated White (73%), non-Hispanic women (77%), and nursing was the most represented medical occupation (35%). Political affiliation, education level, and income were shown to be significant factors associated with vaccination status. Our data suggest that the current allocation of healthcare workers into dichotomous groups such as “anti-vaccine vs. pro-vaccine” may be inadequate in accurately tailoring vaccine uptake interventions. We found that healthcare workers that have yet to receive the COVID-19 vaccine likely belong to one of four categories: the misinformed, the undecided, the uninformed, or the unconcerned. This diversity in vaccine hesitancy among healthcare workers highlights the importance of targeted intervention to increase vaccine confidence. Regardless of governmental vaccine mandates, addressing the root causes contributing to vaccine hesitancy continues to be of utmost importance.

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Section: Discussionsupporting

confidence: 72%

Predictors of COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Southern California: Not Just “Anti” vs. “Pro” Vaccine

et al. 2021

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“…Indeed, public health campaigns are crucial to improve COVID-19 vaccination rates and to reach individuals who are vaccine hesitant [164]. An insight is making vaccination easy and promoting autonomy by simplifying services and offering the public choices, so it may increase uptake in those who remain deliberative [165].…”

Section: Vaccination and Herd Immunitymentioning

confidence: 99%

What Happens to the Immune System after Vaccination or Recovery from COVID-19?

Tiyo

Schmitz

Ortega

et al. 2021

Life

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Due to its leading role in fighting infections, the human immune system has been the focus of many studies in the context of Coronavirus disease 2019 (COVID-19). In a worldwide effort, the scientific community has transitioned from reporting about the effects of the novel coronavirus on the human body in the early days of the pandemic to exploring the body’s many immunopathological and immunoprotecting properties that have improved disease treatment and enabled the development of vaccines. The aim of this review is to explain what happens to the immune system after recovery from COVID-19 and/or vaccination against SARS-CoV-2, the virus that causes the disease. We detail the way in which the immune system responds to a SARS-CoV-2 infection, including innate and adaptive measures. Then, we describe the role of vaccination, the main types of COVID-19 vaccines and how they protect us. Further, we explain the reason why immunity after COVID-19 infection plus a vaccination appears to induce a stronger response compared with virus exposure alone. Additionally, this review reports some correlates of protection from SARS-CoV-2 infection. In conclusion, we reinforce that vaccination is safe and important in achieving herd immunity.

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“…Several studies focused on the general population, groups at risk and general practitioners [17][18][19][20][21] identified hesitance as a critical obstacle to vaccination. The lack of confidence, usually due to fear of side effects and doubts about the safety and efficacy of the influence vaccine, puts the success of vaccination programs at risk [22,23].…”

Section: Discussionmentioning

confidence: 99%

Explorative Study Regarding Influenza Vaccine Hesitancy Among HIV-infected Patients

Marchese¹,

Storti²,

Morganti³

et al. 2021

Preprint

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There are scarce data regarding flu vaccination among people with HIV infection (PWHIV). The goal of this explorative study is to assess hesitancy toward influenza vaccination in a group of PWHIV during the pandemic. A questionnaire was administered to 219 patients vaccinated at our clinic during the 2020-2021 campaign. It evaluated subjects’ adherence over the last 3 seasonal vaccination campaigns, vaccine confidence, complacency and convenience, and the effect of the pandemic on the choice to vaccinate. The population was divided into two groups: fully adherent (all 3 campaigns, 117 patients) and non-fully adherent (1 or 2 campaigns, 102 patients). Adherence increased in non-fully adherent group in 2020-2021, but the pandemic did not affect the choice. Misbelieves emerged: influenza vaccine was considered protective SARS-CoV-2 (22.8% of total population); almost half of all patients thought influenza vaccine could improve their CD4+ cell level (57.3% in fully adherent, 40.2% in non-fully adherent, p<0.05). A quarter of the non-fully adherent group would not have vaccinated in a location other than our clinic (24.5% vs 11.9% in fully adherent group, p<0.05). Conclusively, offering a secure and private space for vaccination seems to encourage vaccination; healthcare professionals should improve counselling to increase adherence and correct misbeliefs.

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Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging

Cited by 154 publications

References 54 publications

Predictors of COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Southern California: Not Just “Anti” vs. “Pro” Vaccine

Predictors of COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Southern California: Not Just “Anti” vs. “Pro” Vaccine

What Happens to the Immune System after Vaccination or Recovery from COVID-19?

Explorative Study Regarding Influenza Vaccine Hesitancy Among HIV-infected Patients

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