Predictors of the Prevalence of Dyslipidemia and Influencing Factors for Young Health Examination Cohort: A Cross-Sectional Survey

Zhang, Hui; Kwapong, William Robert; Shao, Mengmeng; Yan, Jueyue; Lin, Xianda; Chen, Bobei; Chen, Keyang

doi:10.3389/fpubh.2020.00400

Cited by 22 publications

(27 citation statements)

References 44 publications

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“…In agreement with one study [ 30 ], our study also revealed that alcohol consumption was statistically associated with the prevalence of dyslipidemia. The relationship between alcohol intake and plasma lipid levels has been studied for decades and is controversial.…”

Section: Discussionsupporting

confidence: 93%

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Abdissa

Hirpa

2022

BMC Cardiovasc Disord

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Purpose Dyslipidemia is a major risk factor for cardiovascular disease (CVD) in diabetic patients and early detection and treatment can reduce its morbidity and mortality. There is little information on the lipid profile of diabetic patients at West Shewa Public Hospitals, Ethiopia. Therefore, this study aimed to investigate the prevalence and related factors of dyslipidemia among adult diabetes on their follow up at West Shewa Public Hospitals, Ethiopia. Methods A facility-based cross-sectional study was conducted from June 1 to September 30, 2020. Data were collected using pre-tested interviewer-administered structured questionnaire. The participants were recruited using a systematic random sampling method. Bivariable and multivariable binary logistic regression were employed to identify the factors associated with dependent variable. Adjusted odds ratios (AOR) were calculated at 95% confidence interval (CI) and p value of < 0.05 was considered as statistically significant. Results A total number of 390 participants with a mean age of 46.45 (± 15.6) years participated in the study. The overall prevalence of dyslipidemia was 81.5% [95% CI 77.4, 85.4] and the most common lipid abnormality was elevated triglycerides (63.3%). According to multivariate analysis being female gender (AOR = 2.93; 95% CI 1.65, 5.23), age above 50 years (AOR = 3.24; 95% CI 1.54, 6.80) and alcohol consumption (AOR = 2.68; 95% CI 1.33, 5.411) were significantly associated with dyslipidemia. Conclusion The majority of study participants had dyslipidemia. Gender, alcohol intake, and age over 50 years were significantly associated with it. Therefore, the results of this study should be taken into account in order to implement appropriate interventions for the identified risk factors.

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Section: Discussionsupporting

confidence: 93%

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Abdissa

Hirpa

2022

BMC Cardiovasc Disord

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“…Compared to women, men had lower levels of HDL-C and signi cantly higher levels of total cholesterol, LDL-C, triglycerides. This nding was similar to that of the previous study, in which a high incidence of dyslipidemia was observed in males than in females [4][5][6].…”

Section: Discussionsupporting

confidence: 92%

“…According to World Bank estimates, the number of stroke and coronary heart disease will increase to 31.77 million and 22.63 million respectively by 2030[9]. Zhang et al [4] found that the prevalence of dyslipidemia in the young population in Wenzhou is relatively high. Young people should increase their health promoting behaviors and consider the factors in uencing dyslipidemia to lower the prevalence of dyslipidemia.…”

Section: Discussionmentioning

confidence: 99%

Analysis of lipid distribution characteristics in a health examination population in Chengdu (2009–2017)

Liang

Zhao

et al. 2020

Preprint

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BackgroundThe prevalence of cardiovascular disease is rapidly increasing in the recent years. Dyslipidemia associated atherosclerosis and other complications are posing a serious threat to human health. The present study aimed to analyze the blood lipids distribution characteristics within a large size of health examination population of Sichuan province, China.MethodThis was a retrospective study conducted in 888,143 subjects (495,599 males and 392,544 females) aged more than 18 years old from the Health Examination Center at West China Hospital, Sichuan University during 2009 to 2017. The blood lipids levels were compared in different age groups and different years.ResultThe blood lipids levels were significantly increased in recent years. The percentage of cases with high lipids levels was significantly higher in males than that in females since 2009 to 2017. Moreover, the blood lipids levels and the percentage of dyslipidemia in aged 51–60 individuals were significantly higher than those in other population every year.ConclusionThe health examination population showed increased percentage of blood lipids levels, and so regular physical examination and lipids control are highly important in aged population.

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“…The association between drinking and plasma lipid levels has been studied for decades and remains controversial [ 28 ]. It has been shown that moderate alcohol consumption may increase levels of HDL-C, APO-A, and decrease levels of LDL-C [ 18 ]. This is consistent with our results.…”

Section: Discussionmentioning

confidence: 99%

“…Alcohol consumption plays an important role in the process of weight gain [ 10 , 11 , 12 , 13 , 14 , 15 ], as it provides a potential source of energy just after fat [ 16 ]. Alcohol consumption is a well-known determinant of serum lipids levels [ 17 , 18 , 19 ]. Moderate alcohol consumption appears to raise levels of high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) while lowering levels of low-density lipoprotein cholesterol (LDL-C), whereas heavy alcohol consumption has an unfavorable effect on serum lipids and lipoproteins [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Four-Way Decomposition of Effect of Alcohol Consumption and Body Mass Index on Lipid Profile

Gao

et al. 2021

IJERPH

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Background: Both obesity and alcohol consumption are strongly associated with dyslipidemia; however, it remains unclear whether their joint effect on lipid profiles is through mediation, interaction, or a combination of the two. Methods: In total, 9849 subjects were selected from the 2009 panel of China Health and Nutrition Survey (CHNS). A four-way decomposition method was used to validate the pathways of drinking and body mass index (BMI) on lipids (total cholesterol, TC; triglyceride, TG; low-density lipoprotein cholesterol, LDL-C; high-density lipoprotein cholesterol, HDL-C; apolipoprotein A, APO-A; and apolipoprotein B, APO-B). Results: According to four-way decomposition, the total effects of drinking on lipids were found to be statistically significant, except for LDL-C. The components due to reference interaction were 0.63, 0.48, 0.60, −0.39, −0.30, and 0.20 for TC, TG, LDL-C, HDL-C, APO-A and APO-B, respectively (p < 0.05 for all). The effect size of pure indirect effect and mediated interaction were 0.001~0.006 (p > 0.05 for all). Further, linear regression models were used to examine the effect of BMI on lipid profiles in drinkers and non-drinkers. The associations of BMI and lipids were higher in all drinkers than in non-drinkers (0.069 versus 0.048 for TC, 0.079 versus 0.059 for TG, 0.057 versus 0.037 for LDL-C, −0.045 versus −0.029 for HDL-C, −0.024 versus −0.011 for APO-A and 0.026 versus 0.019 for APO-B, p interaction <0.05 for all). Conclusions: The joint effect of alcohol consumption and obesity on lipid profiles is through interaction rather than mediation. Alcohol consumption amplifies the harmful effect of BMI on lipid profiles. Greater attention should be paid to lipid health and cardiovascular risk in obese individuals regarding alcohol consumption. For obese individuals, we do not recommend alcohol consumption.

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Predictors of the Prevalence of Dyslipidemia and Influencing Factors for Young Health Examination Cohort: A Cross-Sectional Survey

Cited by 22 publications

References 44 publications

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Analysis of lipid distribution characteristics in a health examination population in Chengdu (2009–2017)

Four-Way Decomposition of Effect of Alcohol Consumption and Body Mass Index on Lipid Profile

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