Predictors of systolic blood pressure in post-menopausal euthyroid women: A study of the NHANES continuous survey data 2007–2012

Abstract

There is an increased risk of cardiovascular disease and higher rate of hypertension in post-menopausal (compared to pre-menopausal women). We analysed the cross-sectional National Health and Nutritional Examination and Survey 2007-2012 to look at the factors that affect systolic blood pressure in post-menopausal women. We also performed a linear regression with systolic blood pressure as the dependent variable and age, body mass index, total cholesterol, triglycerides, A1C and serum creatinine as independent variables. In the regression model, only body mass index was a significant predictor of systolic blood pressure (adjusted r (2) of 0. 100, F(6, 740) = 14.74, standard error β = 0.08, standardized coefficient B = 0.31, p < 0.01).

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“…It also adds more weight to body fat content as being the driver of this link. We have shown, among others, the importance of inflammation evident by inflammatory biomarkers profile and adipokines in obese rodents and humans suggesting the pivotal role of adipocytes dysfunction, a hallmark and consequence of obesity, in vascular dysfunction and metabolic syndrome [15][16][17][18][19][20]. Moreover, abnormal renal sodium handling, salt sensitivity and sympathetic over-activity have also been shown to link hypertension and obesity [21,22].…”