Predictors of Suicide in First-Episode Affective and Nonaffective Psychotic Inpatients

González-Pinto, Ana; Aldama, A.; González, Cristina M.; Mosquera, Fernando; Arrasate, M.; Vieta, Eduard

doi:10.4088/jcp.v68n0209

Cited by 47 publications

(18 citation statements)

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“…With regard to suicide, 19.8% of patients had attempted suicide by Year 3, rising to 21% by Year 5, percentages that are in agreement with data from Birchwood et al [ 29 ], van Os et al [ 17 ], Verdoux et al [ 39 ], and Robinson et al [ 35 ], and the mean was similar in the two periods. Two patients committed suicide in the last two years (2.4%); unfortunately, as Birchwood noted, suicide risk does not necessarily fall after the first years of the illness [ 29 , 40 , 41 ].…”

Section: Discussionmentioning

confidence: 99%

Prognostic Value of Affective Symptoms in First-Admission Psychotic Patients

Arrasate

González-Ortega

García-Alocén

et al. 2016

IJMS

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Background: Very little research has been conducted in patients with first-episode psychosis using a dimensional approach. Affective dimensional representations might be useful to predict the clinical course and treatment needs in such patients. Methods: Weincluded 112 patients with first-episode psychosis in a longitudinal-prospective study with a five-year follow-up (N = 82). Logistic analyses were performed to determine the predictive factors associated with depressive, manic, activation, and dysphoric dimensions. Results: High scores on the depressive dimension were associated with the best prognosis. On the other hand, high scores on the activation dimension and the manic dimension were associated with a poorer prognosis in terms of relapses. Only the dysphoric dimension was not associated with syndromic or functional prognosis. Conclusion: Ourresults suggest that the pattern of baseline affective symptoms helps to predict the course of psychotic illness. Therefore, the systematic assessment of affective symptoms would enable us to draw important conclusions regarding patients’ prognosis. Interventions for patients with high scores on manic or activation dimensions could be beneficial in decreasing relapses in first-episode psychosis.

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Section: Discussionmentioning

confidence: 99%

Prognostic Value of Affective Symptoms in First-Admission Psychotic Patients

Arrasate

González-Ortega

García-Alocén

et al. 2016

IJMS

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“…Including only studies using multiple methods to assess suicidal behaviour (Addington, 2004;Bakst et al, 2010;Fedyszyn, 2012;Gonzalez-Pinto, 2007;Sanchez-Gistau, 2013;Togay, 2015), which would have a low risk of information bias, increased the OR and this remained significant (OR 2.46, 95% CI 1.57-3.86, p=<0.0001).…”

Section: Subset and Sensitivity Analysismentioning

confidence: 99%

Depression during first episode psychosis and subsequent suicide risk: A systematic review and meta-analysis of longitudinal studies

McGinty

Haque

Upthegrove

2018

Schizophrenia Research

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“…For those suffering from schizophrenia, the life time risk of suicide and parasuicide is high and the first year of psychosis has been reported as a particularly high risk period. 5,[131][132][133][134][135][136] However, within specialized FE programmes, lower rates are being reported. The OPUS trial reported rates of 11% for parasuicide over 1 year, which was associated with hopelessness, hallucinations, parasuicide at baseline and being female.…”

Section: Suicidementioning

confidence: 99%

The promise of early intervention

Addington

2007

Early Intervention Psych

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The focus of this review is the research and clinical work in early psychosis and early intervention which over the past 10-15 years has had a tremendous impact on the field of schizophrenia. Unparalleled progress has been made in programme and service development with a wide range of reported research results, outcome studies, treatment approaches and new initiatives. Traditional areas are being explored in the first episode that can add to our knowledge of schizophrenia. New areas that have a specific relevance for early intervention such as the duration of untreated psychosis and pathways to care are being widely studied. Despite the criticism of the lack of randomized controlled trials, there is a wealth of positive outcome from both effectiveness studies and limited controlled trials. However, there are still many unanswered issues which are in developing stages or which require further investigation.

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Predictors of Suicide in First-Episode Affective and Nonaffective Psychotic Inpatients

Cited by 47 publications

References 0 publications

Prognostic Value of Affective Symptoms in First-Admission Psychotic Patients

Prognostic Value of Affective Symptoms in First-Admission Psychotic Patients

Depression during first episode psychosis and subsequent suicide risk: A systematic review and meta-analysis of longitudinal studies

The promise of early intervention

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