Predictors of Poor Outcome in Female Patients Undergoing Endovascular Intervention

Abbas, Amr E.; Goodman, Laura M.; Timmis, Ryan; Boura, Judith

doi:10.1111/j.1540-8183.2010.00548.x

Cited by 10 publications

(5 citation statements)

References 30 publications

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“…Percutaneous methods are preferred, but outcomes are worse among patients with higher rates of repeat percutaneous angioplasty, subsequent surgical revascularization, or limb loss and death. 166 In another retrospective analysis, CKD 5D patients who underwent percutaneous compared with surgical revascularization experienced higher limb salvage rates. 167 Perioperative morbidity and mortality are high among CKD patients undergoing these procedures.…”

Section: Peripheral Arterial Diseasementioning

confidence: 97%

Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Herzog

Asinger

Berger

et al. 2011

Kidney International

787

576

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Cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD) is high, and the presence of CKD worsens outcomes of cardiovascular disease (CVD). CKD is associated with specific risk factors. Emerging evidence indicates that the pathology and manifestation of CVD differ in the presence of CKD. During a clinical update conference convened by the Kidney Disease: Improving Global Outcomes (KDIGO), an international group of experts defined the current state of knowledge and the implications for patient care in important topic areas, including coronary artery disease and myocardial infarction, congestive heart failure, cerebrovascular disease, atrial fibrillation, peripheral arterial disease, and sudden cardiac death. Although optimal strategies for prevention, diagnosis, and management of these complications likely should be modified in the presence of CKD, the evidence base for decision making is limited. Trials targeting CVD in patients with CKD have a large potential to improve outcomes.

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Section: Peripheral Arterial Diseasementioning

confidence: 97%

Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Herzog

Asinger

Berger

et al. 2011

Kidney International

787

576

View full text Add to dashboard Cite

show abstract

“…9,19,20 Additionally, it has recently been shown that anemia predicts mortality following surgery for colorectal cancer, endovascular intervention for peripheral arterial disease, open vascular reconstruction, and coronary artery bypass grafting. 21 –23 In fact, a recent study has suggested that the presence and severity of preoperative anemia in vascular patients are significant predictors of 30-day and 5-year cardiac events, regardless of underlying heart failure or renal disease. 24 The morbidity and mortality observed in this current series cannot be directly linked to technical issues associated with EVAR, as none of these patients had a proven migration, endoleak, or other significant device-related complication.…”

Section: Discussionmentioning

confidence: 99%

Anemia is Associated With Mortality Following Endovascular Repair of Abdominal Aortic Aneurysm

Saratzis

Melas

Hunter

et al. 2012

Vasc Endovascular Surg

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“… Kuijk et al (2011) [ 147 ] Prevalence of obesity and association on long-term survival; medical treatment at time of discharge and obesity and long-term survival 2,933 6 years ABI < 0.9 or a history of IC with a previous intervention Underweight was an independent predictor of mortality, while overweight protected for all-cause mortality. Abbas et al (2010) [ 124 ] Predictors of poor outcomes in female patients undergoing EI for symptomatic PAD. 292 ~ 2 years Patients who underwent EI Low BMI predicted poor outcomes (subsequent EI and TVR, limb loss, and vascular surgery, death) Kumakura et al (2010) [ 117 ] Long-term survival in patients with PAD and severity of symptoms and association to CKD, and BMI 652 15 years IC or CLI Low BMI was a significant risk factor for mortality Galal et al (2008) [ 116 ] Influence of COPD on the relationship between BMI and mortality in patients with PAD 2,392 4.37 years Vascular surgical interventions (abdominal aortic surgery, carotid endarterectomy), or lower limb arterial revascularization procedures.…”

Section: Impact Of Obesity or Underweight Status On Disease Progressi...mentioning

confidence: 99%

Obesity and Peripheral Artery Disease: Current Evidence and Controversies

et al. 2023

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Purpose of Review Obesity is a significant public health problem and a major risk factor for the development and progression of atherosclerosis and its cardiovascular manifestations. Lower extremity peripheral artery disease (PAD) affects 3%–10% of the Western population and, if left untreated, can lead to devastating outcomes with both an increased risk of morbidity and mortality. Interestingly, the association between obesity and PAD remains debatable. Whereas it is well known that PAD and obesity frequently overlap in the same patients, many studies have demonstrated a negative association between obesity and PAD and a protective effect of obesity on disease development and progression, a phenomenon described as the “obesity paradox.” Possible mechanisms for this paradox may include genetic background, as assessed by mendelian randomization studies, adipose tissue dysfunction, and body fat distribution rather than adiposity, while other factors, such as sex, ethnicity, sarcopenia in the elderly population, or aggressive treatment of co-existing metabolic conditions in individuals with obesity compared to those with normal weight, could have some impact as well. Recent Rindings Few reviews and meta-analyses examining systematically the relationship between obesity and PAD exist. The impact of PAD development due to the presence of obesity remains largely controversial. However, the most current evidence, backed by a recent meta-analysis, suggests a potential protective role of a higher body mass index on PAD-related complications and mortality. Summary In this review, we discuss the association between obesity and PAD development, progression, and management, and the potential pathophysiologic mechanisms linking the two diseases.

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Predictors of Poor Outcome in Female Patients Undergoing Endovascular Intervention

Cited by 10 publications

References 30 publications

Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Anemia is Associated With Mortality Following Endovascular Repair of Abdominal Aortic Aneurysm

Obesity and Peripheral Artery Disease: Current Evidence and Controversies

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