Predictors of outcomes in outpatients with anorexia nervosa – Results from the ANTOP study

Network analysis of specific psychopathology and psychiatric symptoms in patients with anorexia nervosa

“…Hence, effective treatments targeting network of symptoms rather than individual symptoms are expected to focus on central nodes in order to dismantle psychopathologic and symptomatic loops that maintain AN (Costantini et al, 2014). It is still debated whether depression has (Wild et al, 2016) or does not have (Calugi, El Ghoch, Conti, & Dalle Grave, 2014) a prognostic role in determining outcome in AN (hence, any eventual prognostic implication of depressive symptoms' centrality is precluded). On the other hand, a large body of evidence suggests that psychotherapy encompassing wider than "mere" ED-core symptoms psychopathologic aspects, namely, family therapy (FT; Eisler et al, 2016) and enhanced cognitive behavioural therapy (E-CBT) in adolescents (Dalle Grave, Calugi, Doll, & Fairburn, 2013), interpersonal psychotherapy (Linardon, Fairburn, Fitzsimmons-Craft, Wilfley, & Brennan, 2017), or Maudsley model for adults (MANTRA; Schmidt et al, 2015) in adults is an effective treatment for AN.…”

The importance of body image disturbances for the outcome of outpatient psychotherapy in patients with anorexia nervosa: Results of the ANTOP‐study

“…The ANTOP study was conducted as a randomized controlled multicenter trial comparing the efficacy of enhanced cognitive behavioural therapy (CBT‐E) and focal psychodynamic psychotherapy (FPT) to optimized treatment as usual (TAU‐O) in the outpatient psychotherapy of patients with AN (BMI > 15gk/m 2 ). For the results related to primary outcomes of the ANTOP study, see, for example, Zipfel et al () or Wild et al (). For an in‐depth description of the design of the ANTOP study including, for example, detailed descriptions of the applied standardized diagnostic interviews, please see the published study protocol (Wild et al, ).…”

Predictors of outcome among young adult patients with anorexia nervosa in a randomised controlled trial

“…The findings of a recent RCT on adults with AN support the consistent predictors (i.e., higher BMI at baseline and duration of illness). Depression was also related to BMI and recovery at end of treatment (Wild et al, ). Levels of ED symptoms at baseline, patient distress, and confidence in their ability to change predicted ED symptoms at discharge (Goddard et al, ).…”

“…However, contradictory findings have also been presented, indicating that there is no association between outcome and the severity of ED symptoms or weight at admission for AN patients (Abd Elbaky et al, ; McIntosh et al, ). Psychological characteristics measured in terms of the total EDI score have also been found/reported not to predict BMI at follow‐up (Wild et al, ). Increased ED symptoms and general psychopathology have also been shown to predict dropout from treatment (Wallier et al, ), as have lower restraint, high worry about weight, and increased maturity fears (Woodside et al, ).…”