Predictors of Outcome in The Treatment of In-Stent Restenosis with Drug-Eluting Balloons

Abstract

The prognosis of coronary revascularization in patients has been significantly altered by the Interventional cardiology. With the advancement of the novel drugs and stent technology the new complications i.e., in-stent restenosis, have emerged. Objective: To analyze the predictors of outcome in the treatment of in-stent restenosis with drug-eluting balloons. Methods: It was a retrospective study conducted at Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences Gambat for the duration of one year from August 2021 to July 2022. The patients older than 18 years were eligible for the trial. The patients who have undergone coronary intervention with a drug-eluting balloon during the duration of the study were also eligible. This study received approval from the institution's research ethics board. The patient demographic features, procedure complications and operative results were recorded. Results: The mean age of patients was 65 years. There were 62 male participants. There were 54 patients that had history of diabetes mellitus, 87 had hypertension, 32 reported about smoking habits. There were 91 patients that reported about history of percutaneous coronary intervention (PCI), 72 about myocardial infraction (MI) and 30 reported about coronary artery bypass graft (CABG). Kidney related inflammation or infection was found in case of 19 patients. Conclusions: This single center study showed significantly low rate of target lesion revascularization (TLR) for a period of one year and moderate rate was found at five years.