Predictors of Outcome in Acute Stroke Patients: Are They Reliable and Potentially Useful?

Hennerici, Michael G.

doi:10.1159/000479121

Cited by 2 publications

(2 citation statements)

References 6 publications

(6 reference statements)

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“…Atrial fibrillation is a significant cause of cardiogenic stroke [17]. Unhealthy dietary habits, such as the consumption of high-calorie foods, can also exacerbate blood vessel hardening, leading to stroke [18]. As research progresses, more causes of ischemic stroke are likely to be identified.…”

Section: Discussionmentioning

confidence: 99%

The Potential Predicting Value of D-Dimer to Fibrinogen Ratio on Functional Outcome at 1 Year after Acute Ischemic Stroke: A Longitudinal Study

Lin,

Zhou,

Cheng

et al. 2023

Gerontology

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Previous studies have suggested that the D-dimer to fibrinogen ratio (DD/Fg) could be a potential predictor for deep vein thrombosis, pulmonary embolism, and stroke severity. However, the association between plasma DD/Fg and functional outcome following acute ischemic stroke (AIS) has been unclear. Our study followed the STROBE guideline and used a prospective cohort design to investigate this association. Patients with AIS were recruited, and the National Institute of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) were assessed for stroke severity and functional outcome，respectively. We found a significant difference in DD/Fg values between the three groups based on NIHSS scores at admission. Specifically, the DD/Fg values were higher in the poor functional outcome group (mRS score of 2-6) compared to the favorable functional outcome group (mRS score of 0-1) at the 1-year follow-up (P < 0.001). Additionally, the DD/Fg values were independently associated with poor functional prognosis at 1 year following the onset of stroke, even after adjusting for potential confounders (OR 9.21, 95% CI, 3.68–23.02, P<0.001). Our findings suggest that DD/Fg values at admission may serve as risk predictors for poor functional outcomes in patients with AIS 1 year after the stroke.

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Section: Discussionmentioning

confidence: 99%

The Potential Predicting Value of D-Dimer to Fibrinogen Ratio on Functional Outcome at 1 Year after Acute Ischemic Stroke: A Longitudinal Study

Lin,

Zhou,

Cheng

et al. 2023

Gerontology

View full text Add to dashboard Cite

show abstract

“…In addition, refined personalized patient selection criteria are of utmost importance in the interventional procedures to achieve, for example, full recanalization - one of the main parameters associated with early clinical benefit - which depends largely on individual anatomical variability of proximal and intracranial vessels, active collateral capacities, co-existence of atherosclerotic obstructions as well as types of clot formation and obstructions preventing rapid access and retrieving the thrombus [3]. …”

mentioning

confidence: 99%

Predictors of Outcome in Acute Stroke Patients: Are They Reliable and Potentially Useful?

Cited by 2 publications

References 6 publications

The Potential Predicting Value of D-Dimer to Fibrinogen Ratio on Functional Outcome at 1 Year after Acute Ischemic Stroke: A Longitudinal Study

The Potential Predicting Value of D-Dimer to Fibrinogen Ratio on Functional Outcome at 1 Year after Acute Ischemic Stroke: A Longitudinal Study

Endovascular Therapy: More Questions to be Answered for Best Personalized Interventional Treatment

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