Predictors of non-adherence to antihypertensive medication in Kinshasa, Democratic Republic of Congo: a cross-sectional study

Lulebo, Aimée; Mutombo, Paulin; Mapatano, Mala Ali; Mafuta, Eric; Kayembé, Patrick; Ntumba, Lisa T Lt; Mayindu, Alain An; Coppieters, Yves

doi:10.1186/s13104-015-1519-8

Cited by 55 publications

(68 citation statements)

References 29 publications

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“…The low prevalence of other comorbidities in this study could be due to low availability of diagnostic materials and laboratory facilities. The level of comorbidity in our finding is also lower than the findings in Congo (53.9%) [34] which may be related to older age of participants in Congo, the difference in early identification and diagnosis of comorbidities or the difference in life style factors between ours and the Congo population.…”

Section: Discussioncontrasting

confidence: 80%

“…In our study, we excluded patients with depression and other psychiatric disorders. The level of adherence in our study is also higher than the finding in Congo (45.8%) [34]. This noted difference in adherence between ours and Congo may be explained by the difference in socio-demographic characteristics.…”

Section: Discussioncontrasting

confidence: 73%

“…The rate of blood pressure control is better than the findings reported by Goverwa et al (32.8%) from Zimbabwe, Lulebo et al (15.6%) from Congo, and Adebolu et al (42%) from South Africa [12,34,39]. This might be due to high prevalence of physical inactivity, bad dietary habits, obesity, the presence of comorbidities, and elderly population.…”

Section: Discussionmentioning

confidence: 62%

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Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

2016

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BackgroundThe rate of blood pressure control among hypertensive patients is poor and the reasons for poor control of blood pressure remain poorly understood globally.ObjectiveTo assess the rate of blood pressure control among adult hypertensive patients at Jimma University Specialized Hospital.Materials and MethodsWe conducted a hospital based cross sectional study among adult hypertensive patients at Jimma University Specialized Hospital hypertension clinic from March 4, 2015 to April 3, 2015. Data on sociodemographic characteristics of the participants and adherence to antihypertensive medication(s) were collected from patients by face to face interview using a pretested structured questionnaire. Comorbidities, antihypertensive medication(s) and blood pressure measurements were collected retrospectively from medical records. Medication adherence was assessed using Morisky’s Medication Adherence Scale-8 score. We did the statistical analysis using chi-square test and binary logistic regression with level of α set at 0.05. Statistical significance was considered for variables with p<0.05.ResultsOut of 311 participants, 286 patients were eligible and were studied. More than half, 154 (53.8%), of the participants were males. The mean age of the participants was 54.8± 12.6 years (range 26 to 94). The majority, 196 (68.53%), of the participants were taking more than one antihypertensive medication. More than one third (39.5%) of the participants were non adherent to their medication(s). The rate of blood pressure control was 50.3%. In a univariate logistic regression analyses, age ≥65 years old (P = 0.008), physical inactivity (p<0.001), chat chewing (P<0.001), adding salt to food (P<0.001), and coffee use (P<0.001) are significantly associated with uncontrolled blood pressureConclusionAlmost half of the hypertensive patients on follow up had uncontrolled blood pressure. We recommend better health education and care of patients to improve the rate of blood pressure control at the hospital.

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Section: Discussioncontrasting

confidence: 80%

Section: Discussioncontrasting

confidence: 73%

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Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

2016

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“…Hasil ini sejalan dengan penelitian yang dilakukan oleh Lulebo, 22 yang menyatakan bahwa tidak terdapat korelasi antara lamanya menderita suatu penyakit dengan kepatuhan seseorang. Pada umumnya semakin lama orang menderita suatu penyakit maka ia akan semakin paham terhadap penyakit yang dideritanya, namun hasil yang berbeda juga ditemukan, yaitu semakin lama durasi seseorang menderita suatu penyakit maka akan menjadi faktor pemicu seseorang menjadi bosan terhadap pengobatan sehingga menurunkan kepatuhan dalam menjalani terapi.…”

Section: Pembahasanunclassified

Medication Adherence among Hypertensive Patients in Primary Healthcare in Bandung City

Sinuraya¹,

Destiani

Puspitasari

et al. 2018

Indones J Clin Pharm

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“…Indeed, it is surprising that knowledge of hypertensive medicines and the complications of hypertension had no effect on adherence considering results of prior SSA studies. A study assessing adherence to anti-hypertensive therapy among 395 patients in the Democratic Republic of Congo found that poor knowledge of complications and a lack of education to hypertensive patients was significantly associated with nonadherence [10], while in Ethiopia and Algeria, a positive association has been reported between knowledge about hypertension, its treatment and complications, and good adherence [11,12]. Furthermore, In Lesotho and Zimbabwe, inadequate knowledge of hypertension was significantly associated with uncontrolled hypertension [13,14].…”

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confidence: 99%

Find and Plug the Leak: Improving Adherence to Anti-Hypertensive Medicines

Njuguna

Vedanthan

2017

Cardiovasc Drugs Ther

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Elevated blood pressure is the leading preventable cause of cardiovascular disease (CVD) death and disability globally [1,2]. Adherence to anti-hypertensive medicines is the cornerstone to blood pressure control and subsequent reductions in CVD related death and disability [3]. However, adherence to anti-hypertensive medicines remains suboptimal globally and in sub-Saharan Africa (SSA). A recent systematic review estimated rates of non-adherence to be 45% globally, rising to 63% among African and Asian populations [4]. Furthermore, non-adherence was noted in 84% of patients with uncontrolled hypertension. Hypertension prevalence is highest in Africa (46%) compared to other regions and is expected to increase by more than 65% by 2025 [5,6]. Consequently, there is an urgent need to implement strategies to monitor and improve adherence to anti-hypertensive medicines in SSA.Chronic care delivery for hypertension and other noncommunicable diseases (NCDs) remains elusive to a majority of SSA countries where health systems have being designed primarily to address acute infective diseases, maternal and child health, and the HIV epidemic [7]. Where hypertension care is available, socio-economic barriers associated with receiving chronic care limit access and utilisation by patients, with a significant impact on decreasing adherence to medicines [8]. In recognition of this key barrier, some SSA countries have built universal healthcare delivery platforms that provide free or subsidised hypertension care and medicines to their population. However, even in these areas, adherence remains sub-optimal.In Namibia, where universal care for hypertension is provided through public health care (PHC) facilities, Nashilongo et al. assessed the levels and predictors of adherence to antihypertensive medication, and validated a modified version of the Hill-Bone scale for compliance [9]. Their study recruited 120 patients regularly receiving medication refills for hypertensive drugs in four semi-urban PHC facilities in Windhoek. The primary outcome measure was the proportion of patients with ≥80% adherence on the Hill-Bone compliance scale, predefined as acceptable adherence.The modified Hill-Bone Scale for compliance had reasonable internal consistency and construct validity for assessing adherence in this population. Mean adherence level was 77% which was lower than the pre-specified ≥80% level designating good adherence. 58% of patients had adherence levels ≤80%. Independent predictors of good adherence after multivariable logistical regression were having a treatment support buddy, never having missed a clinic appointment, and always attending follow-up visits. Although age and distance to the PHC facility were associated with good adherence on bivariate analysis, these associations were not sustained in the multivariable model. Finally, no association was found between sex, employment status, education level, presence of a comorbidity, and knowledge on hypertension medicines or complications with adherence.Several limitations of thi...

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Predictors of non-adherence to antihypertensive medication in Kinshasa, Democratic Republic of Congo: a cross-sectional study

Cited by 55 publications

References 29 publications

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

Medication Adherence among Hypertensive Patients in Primary Healthcare in Bandung City

Find and Plug the Leak: Improving Adherence to Anti-Hypertensive Medicines

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