Predictors of new-onset atrial fibrillation in elderly patients with acute coronary syndrome undergoing percutaneous coronary intervention

Ulus, Taner; Isgandarov, Kamal; Yılmaz, Ahmet; Vasi, İbrahim; Moghanchızadeh, Sayyed Hamed; Mutlu, Fezan

doi:10.1007/s40520-018-0926-9

Cited by 18 publications

(19 citation statements)

References 26 publications

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“…For the substantial heterogeneity, we performed sensitivity analysis, meta-regression, and subgroup analyses to further explore the explanations. Based on the results, we believe the significant heterogeneity could be described mainly by the inclusion of Ulus et al (2018). Of note, this study did not suggest association between CIN and new-onset AF.…”

Section: Discussionmentioning

confidence: 55%

“…Based on the results, we believe the significant heterogeneity could be described mainly by the inclusion of Ulus et al (2018). Based on the results, we believe the significant heterogeneity could be described mainly by the inclusion of Ulus et al (2018).…”

Section: Discussionmentioning

confidence: 75%

“…However, we found that heterogeneity was attenuated to 14.2% after excluding Ulus et al (2018) (Figure 4). We then conducted meta-regression to determine the effect of this study to overall results.…”

Section: Meta-analysis Resultsmentioning

confidence: 88%

“…Compared to other included studies in our analysis, the study's size was substantially smaller and possibly vulnerable to underpower to detect the correlation. Taking the impact of covariate adjustment into account, the adjusted group (Raposeiras-Roubin et al, 2012;Ulus et al, 2018) was also affected by Ulus et al (2018) with the same reason above, attenuating the association between CIN and new-onset AF to be only modest trend. Furthermore, demographics, ACS types (STEMI, mixed types), and race could also be responsible for the heterogeneity as well as factors not mentioned such as follow-up duration, other ECG parameters, echocardiogram findings, and AF-associated underlying diseases.…”

Section: Discussionmentioning

confidence: 99%

“…F I G U R E 4 Forest plot of subgroup analysis with and without Ulus et al (2018) comparing the occurrence of atrial fibrillation in patients with and without contrast-induced nephropathy horizontal lines represent the 95% CIs with marker size reflecting the statistical weight of the study using random effects model. A diamond data marker represents the overall adjusted OR and 95% CI for the outcome of interest …”

Section: Co N Fli C T O F I Nte R E S Tmentioning

confidence: 99%

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Contrast‐induced nephropathy is associated with new‐onset atrial fibrillation in acute coronary syndrome after cardiac catheterization: Systemic review and meta‐analysis

Prasitlumkum

Kanitsoraphan

Kittipibul

et al. 2019

Noninvasive Electrocardiol

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Introduction Contrast‐induced nephropathy (CIN) is associated with increased cardiovascular morbidity and mortality in patients with acute coronary syndrome (ACS). Recent studies suggest that CIN is associated with new‐onset atrial fibrillation (AF) in patients with acute coronary syndrome (ACS) who underwent catheterization. However, a systematic review and meta‐analysis of the literature have not been done. We assessed the association between CIN in patients with ACS and new‐onset AF by a systematic review of the literature and a meta‐analysis. Hypothesis CIN is associated with new‐onset AF in patients with ACS. Methods We comprehensively searched the databases of MEDLINE and EMBASE from inception to April 2018. Included studies were published cohort studies that compared new‐onset AF after cardiac catheterization in ACS patient with CIN versus without CIN. Data from each study were combined using the random effects, generic inverse variance method of DerSimonian and Laird to calculate risk ratios and 95% confidence intervals. Results Five studies from December 2009 to February 2018 were included in this meta‐analysis involving 5,640 subjects with ACS (1,102 with CIN and 4,538 without CIN). Contrast‐induced nephropathy significantly correlates with new‐onset AF after cardiac catheterization (pooled risk ratio = 2.84, 95% confidence interval: 1.66–4.87, p < 0.001, I2 = 58%) Conclusions Contrast‐induced nephropathy is associated with new‐onset AF threefold among patients with ACS after cardiac catheterization. Our study warranted further study to establish the causality between CIN and new‐onset AF.

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Section: Discussionmentioning

confidence: 55%

Section: Discussionmentioning

confidence: 75%

Section: Meta-analysis Resultsmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Co N Fli C T O F I Nte R E S Tmentioning

confidence: 99%

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Contrast‐induced nephropathy is associated with new‐onset atrial fibrillation in acute coronary syndrome after cardiac catheterization: Systemic review and meta‐analysis

Prasitlumkum

Kanitsoraphan

Kittipibul

et al. 2019

Noninvasive Electrocardiol

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New prognostic factor for hepatitis B virus‐related decompensated cirrhosis: Ratio of monocytes to HDL‐cholesterol

Mao

2021

Clinical Laboratory Analysis

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Hepatitis B virus (HBV) infection is an important health problem worldwide and HBV-infected patients can develop liver failure, liver cirrhosis, and hepatocellular carcinoma, resulting in an annual death toll of more than 1 million patients. 1,2 In China, HBV is the major cause of liver cirrhosis, and approximately 3% of HBV-infected patients with compensated cirrhosis develop decompensated cirrhosis (DeCi) each year, with a 5-year survival rate of only 15%. [3][4][5] Liver transplantation is an only reliable life-prolonging intervention for patients suffering from this condition. However, a shortage of donor livers and serious post-transplantation complications have limited its application. Therefore, identification of specific biomarkers that allow early assessment of prognosis of HBV-DeCi patients has gained importance in clinical practice.It is well known that the systemic inflammatory status plays an important role in the pathogenesis of HBV infection. Several studies have demonstrated that inflammation is relatively common in patients with advanced cirrhosis and associated with poor outcomes. 6,7 Monocyte-to-HDL-cholesterol (HDL-C) ratio (MHR) was a newly proposed inflammatory biomarker. 8 Recently, MHR was reported to be closely associated with coronary heart disease, [9][10][11] atrial fibrillation, 12,13 hypertension, 14 chronic kidney disease, 15 and cerebrovascular accidents. 16 However, no studies have investigated

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The Monocyte to High‐Density Lipoprotein Cholesterol Ratio in the Prediction for Atherosclerosis: A Retrospective Study in Adult Chinese Participants

Zhou

Wang

Jia

et al. 2020

Lipids

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The ratio of monocyte to high‐density lipoprotein cholesterol level (MHR) was a newly proposed inflammatory and oxidative stress marker. This study aimed to explore the association between MHR and Brachial‐ankle pulse wave velocity (Ba‐PWV) in adult Chinese participants. A total of 2029 participants were divided into two groups according to the Ba‐PWV: a high Ba‐PWV group (Ba‐PWV ≥1400 cm/s) and a low Ba‐PWV group (Ba‐PWV < 1400 cm/s). According to the cut‐off points of quartile of MHR, the participants were divided into four groups. The relationship between MHR and Ba‐PWV was analyzed. After adjusting for potential confounders, a non‐linear relationship between MHR and Ba‐PWV was found in the participants, and the inflection point was 7.78 in the non‐linear curve. On the left of the inflection point, MHR had a positive correlation with Ba‐PWV (OR = 1.17, 95% confidence interval (CI): 1.08 to 1.28, p < 0.01). However, there was no obvious relationship between MHR and Ba‐PWV on the right of the inflection point (OR = 0.96, 95% CI: 0.90 to 1.01, p = 0.117). Further demographic analysis demonstrated that the positive relationship between MHR and Ba‐PWV was found in the female participants with hypertension family history, but without a current history of hypertension, smoking, or drinking (p < 0.05). An increased MHR is a risk factor of atherosclerosis, which may predict the potential development of atherosclerosis. When the MHR is close to 7.78, it has the highest predictive value for the risk of atherosclerosis occurrence.

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Predictors of new-onset atrial fibrillation in elderly patients with acute coronary syndrome undergoing percutaneous coronary intervention

Abstract: Prior MI and MHR are independent predictors of NOAF in elderly patients with ACS undergoing PCI. Killip III/IV predicts 6-month overall mortality in such patients.

Cited by 18 publications

References 26 publications

Contrast‐induced nephropathy is associated with new‐onset atrial fibrillation in acute coronary syndrome after cardiac catheterization: Systemic review and meta‐analysis

Contrast‐induced nephropathy is associated with new‐onset atrial fibrillation in acute coronary syndrome after cardiac catheterization: Systemic review and meta‐analysis

New prognostic factor for hepatitis B virus‐related decompensated cirrhosis: Ratio of monocytes to HDL‐cholesterol

The Monocyte to High‐Density Lipoprotein Cholesterol Ratio in the Prediction for Atherosclerosis: A Retrospective Study in Adult Chinese Participants

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