Predictors of Mortality in Ventilated Neonates in Intensive Care Unit

Hossain, M Monir; Shirin, Mahfuza; Mamun, Mohammad Abdullah Al; Hasan, Nurul Akhtar; Sahidullah, Md

doi:10.3329/bjch.v33i3.5687

Cited by 14 publications

(23 citation statements)

References 9 publications

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“…In our study, one-third of admi ed neonates required mechanical ven la on and among them one-third survived (33.3%). Similar to data from other NICUs, in this study outcome was be er with increasing birth weight and gesta onal age 10,11,12,13,14,15 .…”

Section: Discussionsupporting

confidence: 72%

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Clinical Profile and Outcome of Mechanically Ventilated Neonates in a Tertiary Level Hospital

Shrestha

Basnet

Shrestha

2016

J. Nepal Paedtr. Soc.

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Introduction: Many sick neonates admitted to neonatal intensive care unit (NICU) require mechanical ventilation but it is associated with various complications and the outcome of neonates is unpredictable. This study aims to identify the indications for mechanical ventilation, complications, co-morbid conditions and outcome of those neonates in terms of survival. Materials and Methods:Retrospective observational study of all neonates who underwent mechanical ventilation from 1 January 2014 to 31 December 2014 in NICU, Tribhuvan University Teaching Hospital. Medical records of the patients were retrieved from hospital record section to collect the relevant data. Results: One-third of admitted neonates in NICU required mechanical ventilation (MV). Commonest indication was severe respiratory distress (70%) followed by perinatal asphyxia (12%) and recurrent apnea (8%). Disease pattern were sepsis (37.2%), RDS of prematurity (17.6%), perinatal asphyxia (11.7%), meconium aspiration syndrome (9.8%), apnea of prematurity (7.8%) and congenital pneumonia (4%). Hospital acquired sepsis was a major complication occurring in 47% patients on mechanical ventilation. Survival rate among neonates on MV was 33%. Survival was better with increasing birth weight and gestational age. Survival was 100% in congenital pneumonia, 50% in perinatal asphyxia, 50% in recurrent apnea, 26% in sepsis, 20% in MAS and 0% in RDS of prematurity. Conclusion: Survival rate of neonates on mechanical ventilation in NICU was 33%. Sepsis was a major problem in NICU, which must be addressed to improve outcome.

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Section: Discussionsupporting

confidence: 72%

“…The survival rate of neonates on mechanical ven la on in developing countries ranges from 25% to 64% 10,11,12,13,14,15 . In our study, one-third of admi ed neonates required mechanical ven la on and among them one-third survived (33.3%).…”

Section: Discussionmentioning

confidence: 99%

Clinical Profile and Outcome of Mechanically Ventilated Neonates in a Tertiary Level Hospital

Shrestha

Basnet

Shrestha

2016

J. Nepal Paedtr. Soc.

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“…Hossain M et al also observed mean weight of study population as 2171 gm. 15 Gestational age is not statistically associated with outcome of ventilation in present study.…”

Section: 10-contrasting

confidence: 62%

“…This is comparable with the data published. 4,5,[9][10][11][12][13][14][15] We observed that majority of the cases -52 (72.22%) required ventilation for 4-7 days and 3 cases (4.16%) required it for prolonged duration (>10 days). Ahmed SM et al also observed the duration of ventilation as 2-7 days in his study.…”

Section: 10-mentioning

confidence: 99%

Outcome of neonatal ventilation: a prospective and cross-sectional study in tertiary care centre

Sharma

Baheti

2017

Int J Contemp Pediatr

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Background: Neonatal mortality accounts for nearly two thirds of infant mortality and half of under 5 mortalities in India. It is possible to increase neonatal survival and improve the quality of life only through prompt and adequate management of critically ill newborn. Mechanical ventilation has become a must to enhance neonatal survival and is an essential component of neonatal intensive care.Methods: Hospital based prospective, cross-sectional study from 1st July 2012 to 30th June 2013. All NICU admitted neonate requiring mechanical ventilation were included. It was a descriptive, cross-sectional study of a prospective data.Results: Indication of mechanical ventilation: Out of 72 neonates studied, majority of preterm were ventilated for RDS - 34 (89.5%) and majority of Full term were ventilated for MAS - 16 (100%) followed by HIE - 8 (88.89%). Out of 38 RDS cases, 30 (79%) were ventilated till 4-7 days duration and 3 (7.9%) required ventilation for >10 days. Out of 16 MAS cases, 10 (62.5%) were ventilated for 4-7 days duration and none required prolonged ventilation. Duration of ventilation is not statistically associated with indication of mechanical ventilation with p=0.301.Conclusions: Mechanical and Pulmonary complications of mechanical ventilation are not statistically significant for outcome of mechanical ventilation but it increases length of NICU stay. Hypotension on ventilator, requirement of more than 3 ionotropes were associated with high mortality.

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“…3,9,10 In a local study fatality rate was higher than our study and it was 75.5%. 7 Differences in outcome of ventilated neonates between developed and developing countries may be related to the ready availability of surfactant and parenteral nutrition in developed countries as compared to developing countries. Limited manpower, technical expertise and technological advances in developing countries may also be an additional factor.…”

Section: Resultsmentioning

confidence: 99%

Immediate Outcome of Mechanically Ventilated Neonates: Experience from a Tertiary Care Hospital

et al. 2016

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Predictors of Mortality in Ventilated Neonates in Intensive Care Unit

Cited by 14 publications

References 9 publications

Clinical Profile and Outcome of Mechanically Ventilated Neonates in a Tertiary Level Hospital

Clinical Profile and Outcome of Mechanically Ventilated Neonates in a Tertiary Level Hospital

Outcome of neonatal ventilation: a prospective and cross-sectional study in tertiary care centre

Immediate Outcome of Mechanically Ventilated Neonates: Experience from a Tertiary Care Hospital

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