Predictors of Mortality in Outpatient Geriatric Evaluation and Management Clinic Patients

Keller, Brenda K.; Potter, Jane

doi:10.1093/geronj/49.6.m246

Cited by 52 publications

(21 citation statements)

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“…Physical Well-Being.-Numerous studies in the United States have shown that older adults' declining ability to perform ADLs or lADLs is associated with greater use of home health care services (Evashwick, Rowe, Diehr, & Branch, 1984;Wolinsky et al, 1983), a greater risk of becoming hospitalized or institutionalized (Branch & Jette, 1982;Wolinsky, Callahan, Fitzgerald, & Johnson, 1993), and increased mortality (Bernard et al, 1997;Fillenbaum, 1985;Keller & Potter, 1994;Manton, 1988;Wolinsky et al, 1983). In a recent study, Bernard and colleagues (1997) found, for elderly persons in the National Survey of Self-Care and Aging, that individuals who rated themselves as "not at all able" to care for themselves incurred a tenfold increase in their risk of death during the 2.5-year follow-up period compared to those who rated themselves as "completely able" to care for themselves (see also Greiner, Snowdon, & Greiner, 1996;Keller & Potter, 1994).…”

Section: Consequences Of Everyday Competencementioning

confidence: 99%

“…In a recent study, Bernard and colleagues (1997) found, for elderly persons in the National Survey of Self-Care and Aging, that individuals who rated themselves as "not at all able" to care for themselves incurred a tenfold increase in their risk of death during the 2.5-year follow-up period compared to those who rated themselves as "completely able" to care for themselves (see also Greiner, Snowdon, & Greiner, 1996;Keller & Potter, 1994). These findings have been replicated mostly by representative studies in Japan (Koyano et al, 1988;Liu et al, 1995) and Italy (Ferrucci et al, 1991) that show that the odds of mortality are dramatically increased for individuals with deficits in functional status and tasks of daily living.…”

Section: Consequences Of Everyday Competencementioning

confidence: 99%

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Everyday Competence in Later Life: Current Status and Future Directions

Diehl

1998

The Gerontologist

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This article reviews the literature on the antecedents and outcomes of everyday competence in later life and discusses future directions. It is argued that there is a fairly solid knowledge base with regard to the antecedents and outcomes but not in terms of the components and mechanisms of older adults' everyday competence. Five key issues are identified and discussed in terms of a future research agenda. For each key issue, directions for future research are outlined and a transactional approach is advocated. It is emphasized that older adults should be viewed as proactive individuals who are motivated to minimize the losses and maximize the gains associated with the aging process.

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Section: Consequences Of Everyday Competencementioning

confidence: 99%

Section: Consequences Of Everyday Competencementioning

confidence: 99%

Everyday Competence in Later Life: Current Status and Future Directions

Diehl

1998

The Gerontologist

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“…Therefore, the assessment of comorbidities should be integrated into clinical trials, in addition to functional status, particularly since comorbidities and functional status can be used independently to predict outcomes. [5][6][7] Efforts to analyze the impact of comorbidities on index diseases are still in their early stages. The interactions between the index diseases and different comorbidities are variable based on the type and degree of organ involvement.…”

Section: Introductionmentioning

confidence: 99%

Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT

Sorror

Maris

Storb

et al. 2005

Blood

2,493

1,196

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We previously reported that the Charlson Comorbidity Index (CCI) was useful for predicting outcomes in patients undergoing allogeneic hematopoietic cell transplantation (HCT). However, the sample size of patients with scores of 1 or more, captured by the CCI, did not exceed 35%. Further, some comorbidities were rarely found among patients who underwent HCT. Therefore, the current study was designed to (1) better define previously identified comorbidities using pretransplant laboratory data, (2) investigate additional HCT-related comorbidities, and (3) establish comorbidity scores that were suited for HCT. Data were collected from 1055 patients, and then randomly divided into training and validation sets. Weights were assigned to individual comorbidities according to their prognostic significance in Cox proportional hazard models. The new index was then validated. The new index proved to be more sensitive than the CCI since it captured 62% of patients with scores more than 0 compared with 12%, respectively. Further, the new index showed better survival prediction than the CCI (likelihood ratio of 23.7 versus 7.1 and c statistics of 0.661 versus 0.561, respectively, P < .001). In conclusion, the new simple index provided valid and reliable scoring of pretransplant comorbidities that predicted nonrelapse mortality and survival. This index will be useful for clinical trials and patient counseling before HCT. (Blood. 2005;106: 2912-2919)

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“…In most gerontological studies, gender differences in relation to IADL are important (Keller and Potter, 1994;Manton et al, 1995;Iwarsson and Isacsson, 1997). The point of departure for the current study (Figure 1) did comprise the latent variable gender, but since the model had to be reduced to enable further computations, this variable was excluded.…”

Section: Discussionmentioning

confidence: 99%