predictors of long-term fatal cardiovascular events after planned percutaneous coronary interventions

Вершинина, Е. О.; Репин, А. Н.

doi:10.15829/1560-4071-2018-11-34-43

Cited by 4 publications

(1 citation statement)

References 26 publications

(30 reference statements)

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“…The frequency of end points in the PCI group was lower than in the OMT group (13.9% vs 27.0%; risk ratio, 0.46; 95% confi dence interval 0.34-0.63; р < 0.001) after 5 years of observation. In general, the study proved that PCI with stenosis functional signifi cance evaluation in the setting of stable IHD have advantage over OMT in terms of deaths, MI, emergency revascularisations in fi ve years of observation [20]. It follows from the aforesaid that the combination of PCI with OMT has the largest clinical and prognostic effects on treatment results.…”

Section: The Place Of Elective Percutaneous Coronary Interventions Inmentioning

confidence: 77%

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

et al. 2019

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The article is a topical literature review of the place of percutaneous coronary interventions in the structure of elective revascularisation procedures, preoperative preparation of patients with stable ischaemic heart disease before percutaneous coronary intervention, the prospects of the technique, taking into account the latest advances in intervention cardiology (intravascular methods for assessing the hemodynamic significance of stenosis, drug eluting stents). Modern data of the early and long-term results of percutaneous coronary intervention are presented, the predictable potentially modifiable risks of adverse events are described, and ways to correct them are discussed. The results of randomised studies comparing the effectiveness of different approaches for managing patients with stable coronary heart disease (medical therapy, percutaneous coronary intervention) are presented, and prospects for using new drugs to improve the early and late outcomes of endovascular revascularisation are discussed.

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Section: The Place Of Elective Percutaneous Coronary Interventions Inmentioning

confidence: 77%

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

et al. 2019

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Risk assessment of remotely fatal cardiovascular events after elective percutaneous coronary intervention

Nalesnik

Repin

2022

Kompleks. probl. serdečno-sosud. zabol.

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Highlights. The frequency of long-term fatal cardiovascular complications in patients with chronic coronary syndrome subjected to selective (non-emergency) percutaneous coronary interventions was estimated.Risk stratification model of long-term fatal cardiovascular complications in patients with chronic coronary syndrome subjected to selective percutaneous coronary interventions has been created.Aim. To determine the frequency of long-term fatal cardiovascular events (CVE) after elective percutaneous coronary interventions (PCI) and to develop a model for stratifying the risk of these events.Methods. 150 patients with chronic coronary syndrome and indications for endovascular myocardial revascularization were included in the research. After PCI the patients were observed on an outpatient basis for year. The frequency of fatal cardiovascular complications was estimated by telephone interview 6 years after the index intervention.Results. Survival in the study group after 6 years was 86.1%. Fatal CVEs were reported in 10.6% of patients. The following baseline variables were significant predictors of cardiovascular death included in the individual risk assessment model: NYHA functional class of chronic heart failure (odds ratio (OR) 0.06, 95% confidence interval (CI) 0.003-1.106), lean plasma glucose level (OR 0.07, 95% CI 0.12-0.43), atrial fibrillation (OR 43.1, 95% CI 2.01–922.01), as well as the value of creatinine in the blood one year after the intervention (OR 1.14, 95% CI 1.0–1.3) and glomerular filtration rate (CKD-EPI) (OR 1.4, 95% CI 1.09–1.81). The area under the curve (AUC) of the developed model was 0.976 [95% CI 0,000–1,000].Conclusion. The proposed risk stratification model of developing long-term fatal cardiovascular complications in patients with chronic coronary syndrome subjected to selective (non-emergency) PCI allows identifying patients with an unfavorable long-term (six-year) prognosis.

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Azilsartan medoxomil: opportunities and prospects in diabetes mellitus

Кочергина

Барбараш

2021

Arter. gipertenz.

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Current data on the prevalence of hypertension and diabetes mellitus (DM) are presented. Concomitant DM complicates the course of cardiac diseases, affecting the effectiveness of antihypertensive therapy. Along with high blood pressure, lipid and carbohydrate metabolism parameters should be corrected. Nephroprotection is also important in these patients. These goals are achievable due to the pleiotropic effects of some drugs. The analytical paper reviews the pleiotropic organoprotective effects of the antihypertensive drug azilsartan medoxomil. The data on its antihypertensive efficacy versus other angiotensin II receptor blockers are presented. In addition, the results of clinical trials in patients with various components of the metabolic syndrome (obesity, dyslipidemia, hyperglycemia) and DM are described.

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predictors of long-term fatal cardiovascular events after planned percutaneous coronary interventions

Cited by 4 publications

References 26 publications

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

Risk assessment of remotely fatal cardiovascular events after elective percutaneous coronary intervention

Azilsartan medoxomil: opportunities and prospects in diabetes mellitus

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