Predictors of in-hospital mortality by logistic regression analysis among melioidosis patients in Northern Malaysia: A retrospective study

Kamaruddin, Mardhiah; Wan-Arfah, Nadiah; Naing, Nyi Nyi; Hassan, Muhammad Radzi Abu; Chan, Huan‐Keat

doi:10.4103/1995-7645.321612

Cited by 1 publication

(3 citation statements)

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“…After applying the multivariable analysis using the Cox model, the final finding did not show any significant predictors towards mortality from melioidosis (Basheer et al, 2021). Based on the type of melioidosis distribution, bacteremia melioidosis showed a significant determinant of mortality from melioidosis in Mardhiah et al (2021a). Many other studies are also in line with the study's findings (Chien et al, 2018;Churuangsuk et al, 2016;Hantrakun et al, 2019;Roslani et al, 2014).…”

Section: Resultssupporting

confidence: 65%

“…Several studies outside Malaysia showed a significant correlation between elevated urea and mortality among melioidosis patients (Cheng et al, 2003;Kirby et al, 2019;Rajendran et al, 2018). Other than that, platelet count was also one of the prognostic factors of mortality from melioidosis in Mardhiah et al (2021a). From the reported findings, it demonstrated that one unit increased platelet will lower the risk of dying by 0.2% for the Cox model.…”

Section: Resultsmentioning

confidence: 88%

“…The relation between older age and mortality from the melioidosis were showed statistically significant in two articles, Abu Hassan et al (2010) and Zueter et al (2016), urea was found to be a prognostic factor towards mortality from melioidosis in study conducted by Mardhiah et al (2021a). The result demonstrating that increased one mmol/L of urea will increase the risk of dying from melioidosis.…”

Section: Resultsmentioning

confidence: 90%

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An overview of the study designs and statistical methods used in the determination of predictors of melioidosis mortality in Malaysia: 2010-2021

Mardhiah,

Nursyahiyatul-Anis

2024

PEDAGOGICAL RES

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Background: In Malaysia, the mortality from melioidosis infection was reported to be higher than in other infectious diseases. The research on melioidosis is still limited in Malaysia but slightly increasing. Objectives: The objective of the study was to give an overview of the study designs, statistical methods, and comparison of research in identifying the predictors of melioidosis mortality in Malaysia between January 2010 to December 2021. Data sources: Pubmed/Medline. Study eligibility criteria: Original English-language articles were abstracted. The articles that identified the predictors of melioidosis from mortality in Malaysia only included. Letters to the editor, editorials, reviews, systematic reviews, meta-analysis, case reports, and any other ineligible articles were excluded. Results: A total of eight studies were identified related to predictors of melioidosis mortality in Malaysia. From the selected articles, 87.5% were retrospectively collected. Five out of eight articles (62.5%) used the logistic regression in identifying the predictors of melioidosis mortality. Only one (12.5%) used advanced survival analysis methods of Cox regression analysis. Another 25.0% used Chi-square test. Conclusions: Logistic regression methods remain the most common methods of analysis in publications on predictors of melioidosis mortality in Malaysia while retrospective research designs are preferred. There is a limitation of research in predictors of melioidosis mortality and the use of advanced statistical techniques reported using the melioidosis data in Malaysia. More published research on melioidosis will provide input to the clinicians on a more detailed understanding of how to improve the diagnosis of melioidosis and the prognosis factors of this disease.

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