“…Of 78 studies, 27 studies [ 18 – 44 ] were carried out among general patients, while the remaining studies [ 45 – 95 ] were carried out among specific patients. Seventeen studies [ 18 – 22 , 24 , 26 , 31 , 33 – 35 , 38 , 39 , 41 – 43 , 51 ] reported the prevalence of ADEs leading to hospital admissions, while 30 studies [ 18 , 19 , 22 – 33 , 35 , 37 – 41 , 43 , 44 , 65 , 80 , 85 – 88 , 91 , 95 ] reported the prevalence of ADEs during hospitalization. Twelve studies [ 18 , 19 , 22 , 24 , 26 , 31 , 33 , 35 , 38 , 39 , 41 , 43 ] reported ADE occurrence in both settings.…”