Predictors of financial toxicity and its associations with health-related quality of life and treatment non-adherence in Turkish cancer patients

Ürek, Duygu; Uğurluoğlu, Özgür

doi:10.1007/s00520-021-06491-4

Cited by 14 publications

(16 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nine studies reported financial toxicity as a significant predictor of HRQOL using multivariate regression models. [51][52][53]56,61,65,71,76,77 For instance, every 1-point increase in COST score, which indicated less financial toxicity, improved HRQOL scores measured with different instruments by 0.59 points (FACT-G), 71 0.47 points (University of Washington quality of life), 65 and 0.39 points (FACTprostate cancer). 49 All these regression models were adjusted for sociodemographic factors.…”

Section: Multivariate Analysesmentioning

confidence: 99%

“…49 All these regression models were adjusted for sociodemographic factors. These included age, [51][52][53]56,58,61,65,71,76,77 employment status, 53,56,76,77 education, 51,53,76,77 race, 52,53,71 sex, 71,77 (loss of) income, 65,71 and marital status. 51,76 Furthermore, in several studies, the regression models were controlled for clinical variables, such as comorbidities, 51,61 cancer type, 71,76 cancer stage, 53,71 and cancer recurrence.…”

Section: Multivariate Analysesmentioning

confidence: 99%

“…These included age, [51][52][53]56,58,61,65,71,76,77 employment status, 53,56,76,77 education, 51,53,76,77 race, 52,53,71 sex, 71,77 (loss of) income, 65,71 and marital status. 51,76 Furthermore, in several studies, the regression models were controlled for clinical variables, such as comorbidities, 51,61 cancer type, 71,76 cancer stage, 53,71 and cancer recurrence. 53,71 Four other studies estimated multivariate regression models differently by using HRQOL to predict financial toxicity.…”

Section: Multivariate Analysesmentioning

confidence: 99%

See 2 more Smart Citations

Comprehensive Score for Financial Toxicity and Health-Related Quality of Life in Patients With Cancer and Survivors: A Systematic Review and Meta-Analysis

Pangestu

Rencz²

2023

Value in Health

View full text Add to dashboard Cite

Section: Multivariate Analysesmentioning

confidence: 99%

Section: Multivariate Analysesmentioning

confidence: 99%

Section: Multivariate Analysesmentioning

confidence: 99%

See 1 more Smart Citation

Comprehensive Score for Financial Toxicity and Health-Related Quality of Life in Patients With Cancer and Survivors: A Systematic Review and Meta-Analysis

Pangestu

Rencz²

2023

Value in Health

View full text Add to dashboard Cite

“…As a new concern that has emerged in the last decade, a high prevalence of financial toxicity was reported in patients with various cancers worldwide 7–9. Factors related to financial toxicity were identified, involving baseline factors, cancer-related factors, medical insurance status, treatments, end-of-life care and so on 8 10. Furthermore, financial toxicity negatively affects the patient’s treatment, prognosis, quality of life (QoL), symptom burden and so on 7–10.…”

Section: Introductionmentioning

confidence: 99%

“…Factors related to financial toxicity were identified, involving baseline factors, cancer-related factors, medical insurance status, treatments, end-of-life care and so on 8 10. Furthermore, financial toxicity negatively affects the patient’s treatment, prognosis, quality of life (QoL), symptom burden and so on 7–10. Strategies to reduce financial toxicity have also been proposed at multiple levels (provider, clinic, hospital, insurance and governmental, and so on) 7 8 11…”

Section: Introductionmentioning

confidence: 99%

Financial toxicity in patients with lung cancer: a scoping review protocol

Zhuang

Luo

et al. 2022

BMJ Open

View full text Add to dashboard Cite

IntroductionLung cancer has the second-ranked morbidity rate and the first-ranked mortality rate worldwide. With the progression of the cancer condition and the advancement of new treatments, the corresponding medical expenses have risen sharply. Nowadays, financial toxicity has become one of the most common concerns in patients with cancer. However, by far, the full landscape of studies on financial toxicity is unclear in patients with lung cancer. Thus, this scoping review aims to summarise the degree, affecting factors, outcomes and intervention strategies of financial toxicity in patients with lung cancer.Methods and analysisThis scoping review will be developed following the methodology described in the Joanna Briggs Institute Manual for Evidence Synthesis on scoping review protocol, which was based on Arksey and O’Malley’s methodological framework, Levac et al’s recommendations for applying this framework and Peters et al’s enhancements of the framework. From the day of database building to 31 December 2021, 10 English databases will be searched in the ‘Abstract’ field with three key search terms: “Lung”, “Cancer” and “Financial toxicity”. The studies’ screening and data extraction will be independently performed by two reviewers (MZ and RZ). Any disagreements between the two reviewers (MZ and RZ) will be resolved by consensus, and a third reviewer (BW) will be invited if necessary. The results will be analysed and presented using tables and figures. This scoping review will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist.Ethics and disseminationAn ethical approval is not required for this scoping review protocol, nor for the scoping review. The results of this scoping review will be disseminated through publication in a peer-reviewed journal or presentation at conferences.RegistrationThis scoping review protocol has been registered in the Open Science Framework (https://osf.io/ub45n/?view_only=bb93eb94e1434a0f8196b3b61cffcec2).

show abstract

Financial well‐being as a mediator of the relationship between multimorbidity and health‐related quality of life in people with cancer

Chan

et al. 2023

Cancer Medicine

View full text Add to dashboard Cite

BackgroundIt is unknown whether financial well‐being mediates the impact of multimorbidity on the health‐related quality of life (HRQoL) of cancer patients.MethodsParticipants were recruited from three outpatient oncology clinics of Hong Kong public hospitals. Multimorbidity was assessed using the Charlson Comorbidity Index. Financial well‐being, the mediator of the association between multimorbidity and HRQoL outcomes, was assessed using the Comprehensive Score for Financial Toxicity Functional Assessment of Chronic Illness Therapy. The HRQoL outcomes were assessed using the Functional Assessment of Cancer Therapy – General (FACT‐G) and its four sub‐dimensions. Mediation analyses were conducted using SPSS PROCESS v4.1.ResultsSix‐hundred and forty cancer patients participated in the study. Multimorbidity had a direct effect on FACT‐G scores independent of financial well‐being (β for path c’ = −0.752, p < 0.001). In addition, multimorbidity had an indirect effect on FACT‐G scores through its effect on financial well‐being (β for path a = −0.517, p < 0.05; β for path b = 0.785, p < 0.001). Even after adjustments were made for the covariates, the indirect effect of multimorbidity on FACT‐G via financial well‐being remained significant, accounting for 38.0% of the overall effect, indicating partial mediation. Although there were no statistically significant associations between multimorbidity, social well‐being, and emotional well‐being, the indirect effects of multimorbidity on physical and functional well‐being through financial well‐being remained significant.ConclusionsPoor financial well‐being attributable to multimorbidity partially mediates the direct impact of chronic conditions on HRQoL in Chinese cancer patients, particularly their physical and functional well‐being.

show abstract

Predictors of financial toxicity and its associations with health-related quality of life and treatment non-adherence in Turkish cancer patients

Cited by 14 publications

References 34 publications

Comprehensive Score for Financial Toxicity and Health-Related Quality of Life in Patients With Cancer and Survivors: A Systematic Review and Meta-Analysis

Comprehensive Score for Financial Toxicity and Health-Related Quality of Life in Patients With Cancer and Survivors: A Systematic Review and Meta-Analysis

Financial toxicity in patients with lung cancer: a scoping review protocol

Financial well‐being as a mediator of the relationship between multimorbidity and health‐related quality of life in people with cancer

Contact Info

Product

Resources

About