“…5 In previous research, factors related to unemployment have been found to include level of disability (generally measured by the Expanded Disability Status Scale [EDSS]), 1,6,7 age, 1,2,8,9 cognitive functioning, [8][9][10] education level, 7,9,11,12 disease subtype, 2,13 disease duration, 2,8 and gender. 1 In one of the larger studies (N = 1310) on employment and MS, Roessler et al 14 evaluated the relationship of persistence of symptoms, severity of symptoms, educational attainment, affective symp-toms (yes/no), and cognitive symptoms (yes/no) with the categorical outcome variable, employed/not employed, and found that persistence and severity of symptoms, education, and presence of cognitive symptoms were related to employment status. In general, however, study findings have been inconsistent, with little examination of the role of multiple secondary health factors and conditions on employment.…”