Predictors of Early Deterioration and Mortality in Black Americans With Spontaneous Intracerebral Hemorrhage

Qureshi, Adnan I.; Safdar, Kamran; Weil, E. Jennifer; Carol,; Bliwise, Donald L.; Colohan, Austin R. T.; MacKay, Bruce R.; Frankel, Michael

doi:10.1161/01.str.26.10.1764

Cited by 164 publications

(97 citation statements)

References 25 publications

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“…Neither age >65 years and gender affect the outcome of the patients as reported in a study. 27 Hematoma volume >30 ml predicts poor outcome as already proved in other studies. 16,21 Although site of hematoma was reported to affect outcome, 21 we did not found any correlation between the site and functional outcomes.…”

Section: Discussionsupporting

confidence: 53%

30-days’ outcome of haemorrhagic stroke: correlation between intracerebral hemorrhage score and modified Rankin score

Sarder

Mondal

et al. 2018

Mediscope

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Intracerebral hemorrhage (ICH) constitutes 10% to 15% of all strokes. Within 30 days reported mortality is 35-52% and only 20% is functionally independent in 6 months. Despite several existing outcome prediction models for ICH, modified Rankin scale is found to be best predictor of outcome in early and long term period. To find out 30-day mortality in ICH and predict outcome based on modified Rankin score. In this study, 48 patients presenting with acute ICH presenting to a tertiary hospital in Khulna were enrolled. The 30-day mortality and disability were recorded, and ICH score along with modified Rankin score at presentation were calculated. In this study, the 30-day mortality rate was 27.1%; regression analysis showed the correlation between the scores (as measured by modified Rankin scale) for patient disability, intraventricular hemorrhage, the Glasgow Coma score, and volume of hematoma (>30 ml vs <30 ml) were significantly correlated with corresponding ICH scores. The ICH scale is a simple clinical grading scale which can predict mortality as well as disability in haemorrhagic stroke within 30 days that can be helpful to physicians in prioritization of their patient management and forecasting about prognosis.Mediscope Vol. 5, No. 1: Jan 2018, Page 10-14

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Section: Discussionsupporting

confidence: 53%

30-days’ outcome of haemorrhagic stroke: correlation between intracerebral hemorrhage score and modified Rankin score

Sarder

Mondal

et al. 2018

Mediscope

View full text Add to dashboard Cite

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“…The method used was given in only 9 studies; 5 used "clinic" BP measurement, 3 used both "clinic" BP measurement and ambulatory BP monitoring, and 1 used ambulatory BP monitoring alone. The criteria used to define high BP varied considerably: SBP thresholds ranged from 150 to 200 mm Hg, 16 -18 MABP levels of 140 to 145 mm Hg, 16,19 and DBP between 90 and 115 mm Hg. 16,20 -22 One article did not specify the criteria used for defining high BP 23 ; this study was analyzed with the publications that dichotomized according to MABP.…”

Section: Resultsmentioning

confidence: 99%

High Blood Pressure in Acute Stroke and Subsequent Outcome

2004

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Abstract-High blood pressure (BP) is common in acute stroke and might be associated with a poor outcome, although observational studies have given varying results. In a systematic review, articles were sought that reported both admission BP and outcome (death, death or dependency, death or deterioration, stroke recurrence, and hematoma expansion) in acute stroke. Data were analyzed by the Cochrane Review Manager software and are given as odds ratios (ORs) or weighted mean differences (WMDs) with 95% confidence intervals (CIs Key Words: stroke, thrombotic Ⅲ stroke, hemorrhagic Ⅲ blood pressure Ⅲ morbidity Ⅲ mortality H igh blood pressure (BP Ͼ140/90 mm Hg, as defined by the World Health Organization) occurs in acute stroke in up to 75% of cases. 1,2 Subsequently, BP settles over a period of about a week, although Ϸ40% of patients remain hypertensive. The causes of this pathophysiologic response are multifactorial and are related to preexisting high BP, activation of the neuroendocrine systems (sympathetic nervous system, renin-angiotensin axis, and glucocorticoid system), increased cardiac output, and "white coat hypertension." [3][4][5][6][7] It has been suggested that high BP is associated with a poor outcome after acute stroke, although the results of observational studies have given conflicting results. Some authors have even demonstrated better outcomes in patients with high initial BP. 8,9 Data from the International Stroke Trial (IST) confirmed that the risk of early death and late death or dependency was independently associated with increasing systolic BP (SBP) in 17 398 patients. 10 We report here a systematic review of observational studies of BP and outcome and assess the relation between the two. Methods Study IdentificationPublished observational studies that reported baseline BP and outcome (death, death or dependency, or death or deterioration) or mechanisms for poor outcome (recurrent stroke, hemorrhagic transformation, development of cerebral edema, or hematoma expansion) in acute (Ͻ7 days) stroke were sought. Systematic searches of EMBASE and PUBMED were made by M.W. The search strategy used 10 key words: blood pressure, hypertension, outcome, prognosis, death, mortality, recovery, stroke, cerebr*, and acute. Additional studies were found from reference lists of identified articles and reviews. 11-13 Disability or dependency was typically measured with the Barthel Index or Rankin Scale; deterioration was defined as worsening on a stroke neurologic impairment scale, eg, National Institutes of Health stroke scale, or where an ordinal scale (eg, "improved," "unchanged," or "worse") was used. Publications were excluded if they were a randomized trial (these tend not to enroll consecutive patients and might therefore have a biased sample), gave insufficient data, used other outcomes, or were duplicate articles. Decisions on inclusion and exclusion of studies were made by M.W. and P.M.W.B. Data ExtractionTwo authors (M.W. and J.L.-B.) independently extracted data; discrepancies were resolved by P.M.W...

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“…Our findings of initial GCS score between patients with hematoma expansion and without hematoma expansion did not show as an indicator of hematoma expansion. Initial GCS score has known to be associated with patients' clinical outcome regardless of hematoma expansion rather than risk factor of hematoma expansion 3,27,32) . It has been hypothesized by many that certain shape of the hematoma, volume of hematoma and location of hematoma on initial CT scans are associated with presence of hematoma expansion.…”

Section: Discussionmentioning

confidence: 99%

Role of 'Spot Sign' on CT Angiography to Predict Hematoma Expansion in Spontaneous Intracerebral Hemorrhage

Park

Kong

Kim

et al. 2010

J Korean Neurosurg Soc

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Predictors of Early Deterioration and Mortality in Black Americans With Spontaneous Intracerebral Hemorrhage

Abstract: Hemorrhage volume and ventricular extension are the best predictors of early deterioration and mortality in black Americans with SICH.

Cited by 164 publications

References 25 publications

30-days’ outcome of haemorrhagic stroke: correlation between intracerebral hemorrhage score and modified Rankin score

30-days’ outcome of haemorrhagic stroke: correlation between intracerebral hemorrhage score and modified Rankin score

High Blood Pressure in Acute Stroke and Subsequent Outcome

Role of 'Spot Sign' on CT Angiography to Predict Hematoma Expansion in Spontaneous Intracerebral Hemorrhage

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