Predictors of distress and poorer quality of life in High Grade Glioma patients

Halkett, Georgia; Lobb, Elizabeth; Rogers, Michelle M.; Shaw, Thérèse; Long, Andrew; Wheeler, Helen; Nowak, Anna K.

doi:10.1016/j.pec.2015.01.002

Cited by 56 publications

(75 citation statements)

References 27 publications

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“…Second, and similar to previous studies [58,59] the SWB score was higher than the normative values at all test points showing that patients experience increased social support from friends and families, which might lead to an improvement of the HRQOL. Third, previous study confirms that hope is a source of strength that helps individuals to remain active [60,61], brings purpose and meaning to life, encourages a positive attitude and improves psychological well-being [62].…”

Section: Discussionsupporting

confidence: 88%

Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study

et al. 2015

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The diagnosis of a high-grade glioma usual is followed by functional impairment(s), cognitive decline and an impaired psycho-social well-being. This might well have a significant and negative impact on the health related quality of life. The purpose of this study was to explore physical activity levels, prevalence and severity of anxiety and depressive symptoms and health-related quality of life among patients with a highgrade glioma. This paper is based on a longitudinal mixed methods study. Patients (n = 30) completed questionnaires at 5 time points from time of diagnosis until the final follow-up after 1 year. Scores of Karnofsky Performance Status (KPS), physical activity, anxiety and depression and health-related quality of life (FACT-Br) are obtained. Patients' physical activity level and KPS decrease during the disease- and treatment trajectory. The majority of patients did not report any depressive symptoms, eight individuals (26.7 %) being depressed at various time points. Among a sub-group of participants who completed all study requirements for the entire study period the level of anxiety decreased significantly during the study. The FACT-Br sub-scale of emotional well-being increased significant, indicating a better HRQOL attend of followup. The diagnosis of a HGG leads to an ongoing functional decline measured as a decline of the KPS and a reduced physical activity during leisure time. Supportive care combined with rehabilitative and palliative approaches might well be valuable along the trajectory especially during the post-surgery period when anxiety is at its highest peak.

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Section: Discussionsupporting

confidence: 88%

Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study

et al. 2015

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“…It was shown that only 45% of patients were referred to a service provided by a social worker (Langbecker & Yates, ). Literature advocates for early financial counselling and involvement of social workers (Halkett et al, ).…”

Section: Resultsmentioning

confidence: 99%

“…It was shown that only 45% of patients were referred to a service provided by a social worker (Langbecker & Yates, 2016). Literature advocates for early financial counselling and involvement of social workers (Halkett et al, 2015). Late-stage caregiving is a difficult and challenging experience after an already burdening treatment trajectory.…”

Section: Supportive Care and Palliationmentioning

confidence: 99%

Research agenda for life-threatening cancer

2018

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Objectives The aim of this study was to identify future research agendas that reflect the concerns and unexplored areas of interest for patients with life‐threatening cancer, their relatives and the clinical specialists during the cancer trajectory. Methods Six focus group discussions were conducted addressing two different cancer trajectories: primary malignant brain tumour and acute leukaemia. For each of the two cancer trajectories, separate FGIs were carried out with patients, relatives and clinical specialists to identify important concerns, challenges and uncertainties. The FGIs were video/audio‐recorded, transcribed and thematically analysed within and across FGI groups to construct research topics. Finally, the literature was reviewed for existing evidence concerning the identified research topic(s) to strengthen the suggested research agendas. Results New research agendas related to high‐grade glioma brain tumour and acute leukaemia with corresponding research questions were formulated within the topics of supportive care/palliation, education/information, rehabilitation, complementary and alternative therapy and organization of health care. Conclusion User involvement in identifying research agendas has the potential to improve quality of care for patients and caregivers across the cancer trajectory, while minimizing the gap in research between the healthcare user and healthcare provider.

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“…Previous studies determined the actual situation of quality of life (QOL) of patients with malignant glioma [11], the association between QOL and fatigue [12], and explorations of the patients' way of life [13]. However, there have not been any previous studies focusing on the patients’ way of adjustment to life after discharge, despite the fact that patients with malignant gliomas have a shorter time to recurrence.…”

Section: Introductionmentioning

confidence: 99%

The process of life adjustment in patients at onset of glioma who are receiving continuous oral anticancer drug: A qualitative descriptive study

Amano

Suzuki

2019

International Journal of Nursing Sciences

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Objective Patients with malignant gliomas have to adjust their daily lives because of the threat of impending death and declining abilities. Thus, clarifying the process of life adjustment in such patients would help them lead a normal life. To clarify the process of life adjustment in patients at the onset of glioma, who continuously receive oral anticancer drug. Methods The study institution consisted of two designated cancer centers. Semi-structured interviews were conducted with 10 patients, and the data were analyzed using the Modified Grounded Theory Approach of Kinoshita (M-GTA). Results As a core category representing the process of life adjustment in patients at the onset of glioma, “trials and errors for self-fulfillment even in a limited lifespan” was extracted. Patients began “seeking information about the unfamiliar life-threatening disease,” and “imaging their uncertain lives after the disease and the resulting disability” while “conducting repeated trials and errors to establish coping methods according to their abilities.” When facing difficulties in such trials and errors, they reported “losing self-confidence due to unexpected limitations.” However, they regulated their feelings by “resigning themselves to their unchangeable reality.” Contrarily, as “functional improvement enhanced their motivation to recover,” they attempted to promote functional recovery and organized their daily lives in “fulfilling their desires in their limited lifespan.” Conclusion The process of life adjustment in patients with malignant gliomas involved identifying a way of living despite limited lifespan. To ensure appropriate nursing care for patients at the onset of glioma, it is important to help them establish coping methods in accordance with their abilities.

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Predictors of distress and poorer quality of life in High Grade Glioma patients

Cited by 56 publications

References 27 publications

Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study

Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study

Research agenda for life-threatening cancer

The process of life adjustment in patients at onset of glioma who are receiving continuous oral anticancer drug: A qualitative descriptive study

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