Predictors of depression and anxiety in community dwelling stroke survivors: a cohort study

White, Jennifer; Attia, John; Sturm, Jonathan; Carter, Gregory; Magin, Parker

doi:10.3109/09638288.2014.884172

Cited by 70 publications

(81 citation statements)

References 66 publications

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“…We obtained 100 full texts and six [11, 17–21] fulfilled our eligibility criteria in addition to the 18 studies [9, 10, 22–37] from a previous review [7] which had the same inclusion criteria applied. Figure 1 shows reasons for exclusion.…”

Section: Resultsmentioning

confidence: 99%

Factors Associated with Poststroke Anxiety: A Systematic Review and Meta-Analysis

Wright

Chun

et al. 2017

Stroke Research and Treatment

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Background and Purpose. Anxiety affects 25% of stroke survivors. There are no effective treatments. Poststroke depression, prestroke anxiety and depression, locus of control, coping, confidence, fatigue, and sleep are factors that may be associated with poststroke anxiety and can potentially be targeted by therapy. We systematically reviewed the literature and performed a meta-analysis to identify associations with these factors. Methods. We searched electronic databases from January 2014 to July 2015 to complement a literature search performed from inception to May 2014. Study quality was assessed using an internationally endorsed checklist. We used odds ratios (ORs) to estimate the strength of associations and random-effects modelling to calculate summary effect sizes. Results. There were 24 studies recruiting 15448 patients. Quality of reporting was satisfactory. 13 studies with 2408 patients reported associations between poststroke anxiety and poststroke depression (OR = 4.66, 95% confidence interval: 2.23, 9.74). One study reported association with prestroke anxiety, three with prestroke depression, one with fatigue, and two with sleep. No studies reported on locus of control, coping, or confidence. Conclusion. Poststroke anxiety was associated with depression but there are limited data on other modifiable associations. Further research is needed to identify potential targets for treatment.

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Section: Resultsmentioning

confidence: 99%

Factors Associated with Poststroke Anxiety: A Systematic Review and Meta-Analysis

Wright

Chun

et al. 2017

Stroke Research and Treatment

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“…PSD also appears to be related to the degree of neurological disability and functional impairment, as well as to the social support network, socioeconomic status, and education [35,36]. Identified risk factors for PSF depend upon the study in question, but depression, female sex, and European ethnicity are often implicated [12].…”

Section: Risk Factors For Psd and Psfmentioning

confidence: 99%

“…In most studies, psychosocial factors are predictive of PSD [35,36]. Epigenetics are invoked as a link between psychosocial stressors and the biology that mediates disease onset or outcome [65].…”

Section: Inflammation and The Biological Basis Of Psdmentioning

confidence: 99%

“…The FAS has been validated in healthy cohorts [71]. FAS scores of 10-21 indicate that the patient is "not tired", scores of 22-34 indicate that the patient is "tired", and scores of [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] indicate that the patient is "very tired" [72]. We evaluated the relationship between the biomarkers of inflammation shown in Fig.…”

Section: Inflammation and The Biological Basis Of Psfmentioning

confidence: 99%

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Inflammation and the Silent Sequelae of Stroke

Becker

2016

Neurotherapeutics

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Depression and fatigue are common after stroke and negatively impact the quality of life of stroke survivors. The biological bases of these symptoms are unknown, but an abundance of data point to a role for inflammation. This review highlights evidence supporting the contribution of inflammation to poststroke depression and poststroke fatigue. Potential treatments for poststroke depression and poststroke fatigue are explored, with a special emphasis on those that modulate the immune response.

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“…Perceived functional social support was associated with depression/ depressive symptoms following a stroke in both the acute and chronic stages (12/12 studies 40, 45,[52][53][54][55][56][57][58][59][60][61] perceived functional support at time of stroke 45 ) were significant predictors.…”

Section: Relationship Between Social Support/network and Other Variablesmentioning

confidence: 99%

A systematic review of the impact of stroke on social support and social networks: associated factors and patterns of change

et al. 2016

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Objective: Identify what factors are associated with functional social support and social network post stroke; explore stroke survivors' perspectives on what changes occur and how they are perceived. Data sources:The following electronic databases were systematically searched up to May 2015: Academic Search Complete; CINAHL Plus; E-journals; Health Policy Reference Centre; MEDLINE; PsycARTICLES; PsycINFO; and SocINDEX.Review methods: PRISMA guidelines were followed in the conduct and reporting of this review. All included studies were critically appraised using the Critical Appraisal Skills Program tools. Meta-ethnographic techniques were used to integrate findings from the qualitative studies. Given the heterogeneous nature of the quantitative studies, data synthesis was narrative.Results: 70 research reports met the eligibility criteria: 22 qualitative and 48 quantitative reporting on 4,816 stroke survivors. The qualitative studies described a contraction of the social network, with non-kin contact being vulnerable. Although family were more robust network members, significant strain was observed within the family unit. In the quantitative studies, poor functional social support was associated with depression (13/14 studies), reduced quality of life (6/6 studies) and worse physical recovery (2/2 studies). Reduced social network was associated with depression (7/8 studies), severity of disability (2/2 studies) and aphasia (2/2 studies). Although most indicators of social network reduced post stroke (for example, contact with friends, 5/5 studies), the perception of feeling supported remained relatively stable (4/4 studies).3 Conclusion: Following a stroke non-kin contact is vulnerable, strain is observed within the family unit, and poor social support is associated with depressive symptoms. 4A systematic review of the impact of stroke on social support and social networks: associated factors and patterns of change The social impact of having a stroke is considerable. Stroke survivors take part in fewer social activities 1 , family life is disrupted 2 , and contact with friends and the wider network is vulnerable 3 . Social isolation is a commonly reported sequela, and may disproportionately affect those with aphasia (language difficulties) 4 . The two most relevant systematic reviews in the stroke literature have focused on specific aspects of social support post stroke: the association with health-related quality of life 5 and the impact on working age adults 6 . A comprehensive review that explored all factors associated with social support post stroke including recovery and depression, and which analysed how changes to social support were perceived by the stroke survivor, may enable stroke services to be more sensitively designed.For the purposes of this review social support has been conceptualised in terms of function and structure. For quantitative studies, an additional criterion was that only studies using validated measures of functional support were included: when assessing subjective feelings...

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Predictors of depression and anxiety in community dwelling stroke survivors: a cohort study

Cited by 70 publications

References 66 publications

Factors Associated with Poststroke Anxiety: A Systematic Review and Meta-Analysis

Factors Associated with Poststroke Anxiety: A Systematic Review and Meta-Analysis

Inflammation and the Silent Sequelae of Stroke

A systematic review of the impact of stroke on social support and social networks: associated factors and patterns of change

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