Predictors of costs of care in Alzheimer's disease: A multinational sample of 1222 patients

Abstract

ADL-ability is the most important predictor of societal costs of care in community dwellings irrespective of country and should therefore be central in the economic evaluation of Alzheimer's disease therapies.

Cost-utility analysis of memantine extended release added to cholinesterase inhibitors compared to cholinesterase inhibitor monotherapy for the treatment of moderate-to-severe dementia of the Alzheimer’s type in the US

“…Some of those cost savings are partially offset by increased caregiver costs due to the slightly higher time that caregivers must spend taking care of patients on memantine ER/AChEI in the community. However, this offset is relatively minor: in the US, direct medical costs are nearly 9-times higher in the institutional settings than in the community for moderate-to-severe Alzheimer's patients 27 . Therefore, from a public health perspective, reducing the time spent in an institution by delaying institutionalization by even as little as 3-4 months would have a significant impact on resources consumption associated with AD, and can yield significant savings.…”

“…The proportions of patients with AD using antipsychotics as concomitant drugs are based on estimates from Lachaine et al23 , estimating that 41% of AD patients take antipsychotics for the first 12 months after AD treatment initiation, increasing annually thereafter by 9% and 3% for the AChEI monotherapy and combination arms, respectively. Direct medical costs of care per patient per month are based on estimates published in Gustavsson et al27 and vary by AD severity stage and location of care. Monitoring costs account for physician visits only and assume that one annual visit is required for patients in both treatment arms.…”

fuzzy temporal data-mining model for activity recognition in smart homes /

“…These factors often force patients to be institutionalized, even if most of them wish to stay home as long as possible [1]. Since the cost associated with AD is very high [18] and resources are lacking (e.g. medical staff), governments want to prolong the time people with AD can remain in their homes.…”

“…4-Take the last three t points (7,8,9) and find their average (8); take the last three y points in the table (18,21,19) and find their average (19.3).…”

Comparison of care dependency and related nursing care problems between Austrian nursing home residents with and without dementia

“…Besides care dependency, this study focuses on the nursing care problems of malnutrition, incontinence, pressure ulcers, falls and restraints, because people with dementia are at risk of developing these problems [10][11][12] and the problems themselves are important quality indicators for nursing homes [8,[13][14][15]. Care dependency and nursing care problems can induce negative consequences like reduced quality of life, high health care costs and higher mortality [8,[16][17][18][19]. Adequate care interventions can reduce, stabilize and perhaps even prevent (e.g.…”