Predictors of changes in gait performance over four years in persons with late effects of polio

Flansbjer, Ulla Britt; Lexell, Jan; Brogårdh, Christina

doi:10.3233/nre-162057

Cited by 8 publications

(6 citation statements)

References 26 publications

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“…Among the variables, step length, measured at individuals’ regular walking velocity, showed the highest correlation with the RMS value obtained from the knee flexor during maximal flexion effort (R 2 = 0.1632, p < 0.0001). These results were plausible and consistent with previous reports, suggesting that knee flexion strength is an important predictor of gait performance [ 34 ]. Consistent with this observation, Mañago et al, discovered in their multivariable analysis that knee flexion strength remained a significant variable for predicting gait speed, whereas knee extension did not [ 35 ].…”

Section: Discussionsupporting

confidence: 93%

Predictors of Step Length from Surface Electromyography and Body Impedance Analysis Parameters

Park

Baek

Sung

et al. 2022

Sensors

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Step length is a critical hallmark of health status. However, few studies have investigated the modifiable factors that may affect step length. An exploratory, cross-sectional study was performed to evaluate the surface electromyography (sEMG) and body impedance analysis (BIA) parameters, combined with individual demographic data, to predict the individual step length using the GAITRite® system. Healthy participants aged 40–80 years were prospectively recruited, and three models were built to predict individual step length. The first model was the best-fit model (R2 = 0.244, p < 0.001); the root mean square (RMS) values at maximal knee flexion and height were included as significant variables. The second model used all candidate variables, except sEMG variables, and revealed that age, height, and body fat mass (BFM) were significant variables for predicting the average step length (R2 = 0.198, p < 0.001). The third model, which was used to predict step length without sEMG and BIA, showed that only age and height remained significant (R2 = 0.158, p < 0.001). This study revealed that the RMS value at maximal strength knee flexion, height, age, and BFM are important predictors for individual step length, and possibly suggesting that strengthening knee flexor function and reducing BFM may help improve step length.

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Section: Discussionsupporting

confidence: 93%

Predictors of Step Length from Surface Electromyography and Body Impedance Analysis Parameters

Park

Baek

Sung

et al. 2022

Sensors

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“…The majority of longitudinal studies (14, 25, 104–107) detect progressive muscle weakness, which contributes to deteriorating gait performance (107) and declining mobility (105). Quantifying the rate of decline in PPS is challenging and no reliable functional predictors have been validated.…”

Section: Resultsmentioning

confidence: 99%

Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease

et al. 2019

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Post-polio syndrome (PPS) is a neurological condition that affects polio survivors decades after their initial infection. Despite its high prevalence, the etiology of PPS remains elusive, mechanisms of progression are poorly understood, and the condition is notoriously under-researched. While motor dysfunction is a hallmark feature of the condition, generalized fatigue, sleep disturbance, decreased endurance, neuropsychological deficits, sensory symptoms, and chronic pain are also often reported and have considerable quality of life implications in PPS. The non-motor aspects of PPS are particularly challenging to evaluate, quantify, and treat. Generalized fatigue is one of the most distressing symptoms of PPS and is likely to be multifactorial due to weight-gain, respiratory compromise, poor sleep, and polypharmacy. No validated diagnostic, monitoring, or prognostic markers have been developed in PPS to date and the mainstay of therapy centers on symptomatic relief and individualized rehabilitation strategies such as energy conservation and muscle strengthening exercise regimes. Despite a number of large clinical trials in PPS, no effective disease-modifying pharmacological treatments are currently available.

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“…The limitations in standing and walking, which increased the fall risk and caused emotional reactions of worry and fear of falling, underline the importance of understanding the impact on everyday activities and social participation. It has been shown that the decline in walking (using objective measures) develops slowly over time in people with LEoP [30,31]. Hence, by providing various targeted rehabilitation interventions, such as reducing LEoP-related impairments, adapting the home environment, prescribing appropriate aids and discussing strategies to achieve a good balance between rest and physical activity, walking ability may be sufficiently maintained.…”

Section: Methodological Considerations and Clinical Implicationsmentioning

confidence: 99%

The Influence of Walking Limitations on Daily Life: A Mixed-Methods Study of 14 Persons with Late Effects of Polio

Brogårdh

Lexell

Hammarlund

2022

IJERPH

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Reduced walking ability is common in persons with late effects of polio (LEoP). Here, we explored how many walking limitations persons with LEoP perceive, and how these limitations influence daily life, by using a mixed-methods design. Fourteen persons (mean age 70 years, whereof 7 women) with LEoP responded to the Walking Impact Scale (Walk-12), and were interviewed individually. Qualitative data were analysed by systematic text condensation, and each quotation was deductively analysed in relation to the items in Walk-12. Running was perceived as most limited, whereas walking indoors without using support was perceived as least limited. A majority (>70%) were moderately to extremely limited in standing or walking, in walking speed and distance, which affected concentration and effort, as well as gait quality aspects. The limited walking ability intruded on many everyday activities, both indoors and outdoors, which affected social participation negatively. To increase safety when walking and reduce the fall risk, various strategies were adopted such as using aids, walking carefully, and avoiding risky activities. In conclusion, LEoP-related walking limitations influence participants’ activity and participation greatly. By using both the Walk-12 scale and face-to-face interviews, an increased understanding of how walking limitations influence everyday life was achieved.

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Predictors of changes in gait performance over four years in persons with late effects of polio

Abstract: The small gradual reduction in gait performance over time in persons with late effects of polio is primarily determined by the individual variations in the knee flexor strength.

Cited by 8 publications

References 26 publications

Predictors of Step Length from Surface Electromyography and Body Impedance Analysis Parameters

Predictors of Step Length from Surface Electromyography and Body Impedance Analysis Parameters

Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease

The Influence of Walking Limitations on Daily Life: A Mixed-Methods Study of 14 Persons with Late Effects of Polio

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