Predictors of carbon monoxide poisoning-induced delayed neuropsychological sequelae

Ku, Hsiao Lun; Yang, Kai-Chun; Lee, Ying-Chiao; Lee, Ming-Been; Chou, Yuan-Hwa

doi:10.1016/j.genhosppsych.2009.11.005

Cited by 56 publications

(46 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Significant differences were showed in Chen’s study but neuropsychological assessment was only partial and memory function had not been assessed [2]. Other studies investigating cognitive outcome after CO poisoning did not specifically enroll a group of control subjects but reported results that are in accordance with ours [5,7,14,15]. We acknowledge that our study is cross-sectional.…”

Section: Discussionsupporting

confidence: 60%

Neuropsychological outcome after carbon monoxide exposure following a storm: a case-control study

et al. 2014

View full text Add to dashboard Cite

BackgroundThe cognitive consequences of carbon monoxide (CO) poisoning are well described. However, most studies have been carried out without an ad-hoc group of control subjects. The main aim of this study was to evaluate cognitive and psychiatric outcome after CO exposure during the storm Klaus in the South West of France (January 2009) in a homogeneous group of patients compared to a group of 1:1 paired controls.MethodsPatients and controls were asked to fill out questionnaires about quality of life and cognitive complaints. They then underwent a cognitive assessment derived from the Carbon Monoxide Neuropsychological Screening Battery. Psychiatric assessment was performed using subtests of the Mini International Neuropsychiatric Interview.Results38 patients and 38 paired controls were included (mean age 38.8 years) and evaluated 51 days after the poisoning. No difference was found between groups on the cognitive complaint questionnaire but patients had a lower quality of life than controls. Patients showed significantly lower cognitive performance than controls on processing speed, mental flexibility, inhibition and working and verbal episodic memories. Patients were more depressed than controls, and suffered more from post-traumatic stress disorder.ConclusionsWe report the first study investigating cognitive and psychiatric outcome in consecutive patients after CO poisoning during a natural disaster, using a group comparison method. CO poisoning during storms needs to be dealt with adequately and clinicians should be aware of its possible consequences.

show abstract

Section: Discussionsupporting

confidence: 60%

Neuropsychological outcome after carbon monoxide exposure following a storm: a case-control study

et al. 2014

View full text Add to dashboard Cite

show abstract

“…[20] GCS has been used for predicting delayed neuropsychological sequels of carbon monoxide (CO) poisoning. [5] GCS score equal to or less than 14 had been associated with myocardial injury in CO poisoning. [9] GCS less than eight was more associated with mortality in a study by Budhathoki et al .…”

Section: Discussionmentioning

confidence: 99%

Applicability of different scoring systems in outcome prediction of patients with mixed drug poisoning-induced coma

2011

View full text Add to dashboard Cite

Background:Mixed drugs poisoning (MDP) is common in the emergency departments. Because of the limited number of intensive care unit beds, recognition of risk factors to divide the patients into different survival groups is necessary. Poisoning due to ingestion of different medications may have additive or antagonistic effects on different parameters included in the scoring systems; therefore, the aim of the study was to compare applicability of the different scoring systems in outcomes prediction of patients admitted with MDP-induced coma.Methods:This prospective, observational study included 93 patients with MDP-induced coma. Clinical and laboratory data conforming to the Acute Physiology and Chronic Health Evaluation (APACHE II), Modified APACHE II Score (MAS), Mainz Emergency Evaluation Scores (MEES) and Glasgow Coma Scale (GCS) were recorded for all patients on admission (time0) and 24 h later (time24). The outcome was recorded in two categories: Survived with or without complication and non-survived. Discrimination was evaluated using receiver operating characteristic (ROC) curves and area under the ROC curve (AUC).Results:The mortality rate was 9.7%. Mean of each scoring system was statistically significant between time0 and time24 in the survivors. However, it was not significant in non-survivors. Discrimination was excellent for GCS24 (0.90±0.05), APACHE II24 (0.89±0.01), MAS24 (0.86±0.10), and APACHE II0 (0.83±0.11) AUC.Conclusion:The GCS24, APACHE II24, MAS24, and APACHE II0 scoring systems seem to predict the outcome in comatose patients due to MDP more accurately. GCS and MAS may have superiority over the others in being easy to perform and not requiring laboratory data.

show abstract

“…It is also a leading cause of suicide deaths in Taiwan, Hong Kong, and other Asian countries where suicide by charcoal burning has increased rapidly (Pan et al, 2010;Tsai et al, 2011). The clinical symptoms of CO poisoning are non-specific and varied, including cognitive dysfunctions, personality changes, urine and fecal incontinence, gait disturbances, parkinsonism and other movement problems, depression, anxiety and mutism (Ernst and Zibrak, 1998;Hurley et al, 2001;Kesler et al, 2001;Hay et al, 2002;Parkinson et al, 2002;Porter et al, 2002;Weaver et al, 2002;Pulsipher et al, 2006;Kondziella et al, 2009;Weaver, 2009;Chang et al, 2010;Ku et al, 2010;Yang et al, 2011). The cognitive impairment caused by CO poisoning involves multiple domains, such as attention, visual and verbal memory, executive function, calculation, and visuospatial function (Hurley et al, 2001;Kesler et al, 2001;Hay et al, 2002;Parkinson et al, 2002;Porter et al, 2002;Weaver et al, 2002;Pulsipher et al, 2006;Kondziella et al, 2009;Chang et al, 2010Chang et al, , 2011.…”

Section: Introductionmentioning

confidence: 99%

Longitudinal changes in the dopamine transporter and cognition in suicide attempters with charcoal burning

Yang

Wang

Hsieh

et al. 2015

Psychiatry Research: Neuroimaging

Self Cite

View full text Add to dashboard Cite

Predictors of carbon monoxide poisoning-induced delayed neuropsychological sequelae

Cited by 56 publications

References 28 publications

Neuropsychological outcome after carbon monoxide exposure following a storm: a case-control study

Neuropsychological outcome after carbon monoxide exposure following a storm: a case-control study

Applicability of different scoring systems in outcome prediction of patients with mixed drug poisoning-induced coma

Longitudinal changes in the dopamine transporter and cognition in suicide attempters with charcoal burning

Contact Info

Product

Resources

About