Predictors of Adherence With Antihypertensive and Lipid-Lowering Therapy

Chapman, Richard H.; Benner, Joshua S.; Petrilla, Allison

doi:10.1016/j.accreview.2005.08.206

Cited by 87 publications

(112 citation statements)

References 12 publications

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“…A participant was "adherent" if the MPR was 980 %, based on established literature. 12 All predictors were categorical; bivariate analyses were performed using χ 2 tests. Multivariable logistic regression was performed.…”

Section: Statistical Analysesmentioning

confidence: 99%

Adherence to Chronic Disease Medications among New York City Medicaid Participants

2012

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Medication adherence is critical for cardiovascular disease prevention and control. Local health departments are well positioned to address adherence issues, however relevant baseline data and a mechanism for monitoring impact of interventions are lacking. We performed a retrospective analysis using New York State Medicaid claims from 2008 to 2009 to describe rates and predictors of adherence among New York City Medicaid participants with dyslipidemia, diabetes, or hypertension. Adherence was measured using the medication possession ratio, and multivariable logistic regression was used to assess factors related to adherence. Medication regimen adherence was 63%. Greater adherence was observed in those who were older, male, and taking medications from ≥3 drug classes. Compared with whites, blacks and Hispanics were less likely to be adherent (adjusted odds ratio [OR]=0.67, 95% confidence interval [CI]: 0.65-0.70 and adjusted OR=0.76, 95% CI: 0.73-0.78, respectively), while Asians were as likely. Medication adherence was inadequate and racial disparities were identified in NYC Medicaid participants on stable medication regimens for chronic disease. This study demonstrates a claims-based model that may be used by local health departments to monitor and evaluate efforts to improve adherence and reduce disparities.

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Section: Statistical Analysesmentioning

confidence: 99%

Adherence to Chronic Disease Medications among New York City Medicaid Participants

2012

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“…43 In addition, the simultaneous treatment of multiple risk factors, and frequent requirement for multiple antihypertensive medications to control BP alone, may lead to complex treatment regimens and an associated decrease in patient adherence to therapy. 44 Single-pill amlodipine/atorvastatin therapy could improve patient adherence to concomitant BP and lipid-lowering medications by simplifying the treatment regimen, and synchronising the initiation of CCB and statin therapy. 44,45 In two recent retrospective studies, adherence with single-pill amlodipine/atorvastatin was approximately twice that with amlodipine and atorvastatin co-administered in a two-pill regimen over a 6-month period among patients previously taking either a CCB or a statin (but not both).…”

Section: -Year Framingham Riskmentioning

confidence: 99%

Single-pill amlodipine/atorvastatin helps patients of diverse ethnicity attain recommended goals for blood pressure and lipids (the Gemini-AALA study)

Erdine

Tse

et al. 2008

J Hum Hypertens

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“…However, if such complex treatment regimens and demanding self-care activities are to be effective, a high degree of patient adherence and compliance must be ensured. Several studies have documented that this is not easily achieved [13][14][15]. A study on the implementation of guidelines for the prevention of diabetic nephropathy in type 1 diabetic patients found that 79% did not achieve the target BP of ≤140/≤90 mmHg [16].…”

Section: Introductionmentioning

confidence: 99%

Diabetic patients treated with dialysis: complications and quality of life

et al. 2007

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Aims/hypothesis The aim of this study was to describe the prevalence of complications, health-related quality of life (HRQOL) and the influence of beliefs about control over health in diabetic dialysis patients. Methods Of 53 eligible diabetic patients on chronic dialysis during January 2004 in our clinic, 38 (76%) completed a kidney-specific (Kidney Disease Quality of Life) and a generic (SF-36) questionnaire and were characterised in terms of cardiovascular diseases and diabetic complications. Matched groups of non-diabetic dialysis patients (n= 40) and diabetic patients with a long duration of diabetes and normal kidney function (n=38) served as controls. Generic HRQOL was compared with matched data from a survey on the Danish general population (n=2248).

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Predictors of Adherence With Antihypertensive and Lipid-Lowering Therapy

Cited by 87 publications

References 12 publications

Adherence to Chronic Disease Medications among New York City Medicaid Participants

Adherence to Chronic Disease Medications among New York City Medicaid Participants

Single-pill amlodipine/atorvastatin helps patients of diverse ethnicity attain recommended goals for blood pressure and lipids (the Gemini-AALA study)

Diabetic patients treated with dialysis: complications and quality of life

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