Predictors of adherence to antihypertensive medication in northern United Arab Emirates

Bader, R.J.K.; Koprulu, Fatma; Hassan, Noraryana; Ali, AbdelAziem A.; Elnour, Asim Ahmed

doi:10.26719/2015.21.5.309

Cited by 30 publications

(51 citation statements)

References 27 publications

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“…In United Arab Emirates [32], adherence to antihypertensive medication(s) was reported to be 54.4% which is lower than our finding. This may be attributed to the presence of comorbidities and advanced age of the patients which may significantly affect medication adherence.…”

Section: Discussioncontrasting

confidence: 97%

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

2016

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BackgroundThe rate of blood pressure control among hypertensive patients is poor and the reasons for poor control of blood pressure remain poorly understood globally.ObjectiveTo assess the rate of blood pressure control among adult hypertensive patients at Jimma University Specialized Hospital.Materials and MethodsWe conducted a hospital based cross sectional study among adult hypertensive patients at Jimma University Specialized Hospital hypertension clinic from March 4, 2015 to April 3, 2015. Data on sociodemographic characteristics of the participants and adherence to antihypertensive medication(s) were collected from patients by face to face interview using a pretested structured questionnaire. Comorbidities, antihypertensive medication(s) and blood pressure measurements were collected retrospectively from medical records. Medication adherence was assessed using Morisky’s Medication Adherence Scale-8 score. We did the statistical analysis using chi-square test and binary logistic regression with level of α set at 0.05. Statistical significance was considered for variables with p<0.05.ResultsOut of 311 participants, 286 patients were eligible and were studied. More than half, 154 (53.8%), of the participants were males. The mean age of the participants was 54.8± 12.6 years (range 26 to 94). The majority, 196 (68.53%), of the participants were taking more than one antihypertensive medication. More than one third (39.5%) of the participants were non adherent to their medication(s). The rate of blood pressure control was 50.3%. In a univariate logistic regression analyses, age ≥65 years old (P = 0.008), physical inactivity (p<0.001), chat chewing (P<0.001), adding salt to food (P<0.001), and coffee use (P<0.001) are significantly associated with uncontrolled blood pressureConclusionAlmost half of the hypertensive patients on follow up had uncontrolled blood pressure. We recommend better health education and care of patients to improve the rate of blood pressure control at the hospital.

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Section: Discussioncontrasting

confidence: 97%

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

2016

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“…Participants in the current research revealed nonadherence rate of 81%. Our finding is consistent with previous research findings, and it is relatively higher than what has been reported in other studies . Most of the recent studies which assessed medication nonadherence rates in the Middle East area reported better adherence rates (23–49.5%) .…”

Section: Discussionsupporting

confidence: 93%

Investigation of variables associated with medication nonadherence in patients with hypertension

Jarab

Alefishat

Nasur

et al. 2018

J Pharm Health Serv Res

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Objective Medication nonadherence represents a major barrier to achieve optimal health outcomes in patients with hypertension. The study aim was to identify obstacles to medication adherence in patients with hypertension in Jordan. Methods Socio‐demographic and clinical variables in addition to medication adherence and health‐related quality of life (HRQoL) were assessed for patients attending three major hospitals in Jordan. Multiple logistic regression was carried out to identify predictors of medication nonadherence. Key findings Of the 300 participants, 81% (n = 57) were classified as nonadherent. Both, the increase in the number of prescribed medications (OR = 0.349, CI = 0.17–1.19) and having comorbid illness (OR = 0.315, CI = 0.15–1.02) increased the risk of medication nonadherence by three times. The patients were also found six and eight times less likely to adhere to their medications if they had concerns about medications’ side effects (OR = 0.165, CI = 0.09–0.95) and if they reported poor HRQoL (OR = 0.127, CI = 0.04–0.87) respectively. Conclusions Clinical pharmacists should consider prescribing the least possible number of medications and improving patients’ perceptions about the potential side effects of their medications. Furthermore, patients with comorbid diseases and those with poor HRQoL should be particularly addressed in future pharmaceutical care programs with the aim of improving medication adherence and health outcomes in patients with hypertension.

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“…[27,28] In contrast to our findings, other studies have reported adherence to be higher among people above 60 years of age and females. [23,29] In this study, good adherence was found to be associated with higher level of education and employment in a skilled occupation which may be due to better knowledge about the disease and its treatment. Similar results were obtained in a study done in Iran as well as in India.…”

Section: Discussionmentioning

confidence: 88%

“…[18,25] Good adherence was observed in patients who were on monotherapy, 70.5%, than those on polytherapy, 29.5%, and also among those on once a day prescription, 53.8%, which is similar to the results obtained in various studies done all over the world. [18,23,25,29] This suggests the importance of keeping the prescription of antihypertensive drugs and its dosing to a minimum to improve the treatment compliance. In another study done in North India regarding prescription practices for antihypertensive drugs, it was observed that monotherapy (81.7%) with calcium channel blockers was more common than combination therapy (34.8%).…”

Section: Discussionmentioning

confidence: 99%

“…Various [27] A study conducted in UAE reported the use of traditional remedies for hypertension as an important determinant of nonadherence. [29] A qualitative study done in Spain to determine the factors related to non-compliance identified complex web of factors, including patient-related as well as physicianrelated parameters implicated in non-compliance. The major factors identified were the patients lack of basic knowledge about the disease and a poor physician-patient interaction.…”

Section: Discussionmentioning

confidence: 99%

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A community-based study to assess the treatment adherence and its determinants among hypertensive patients residing in a rural area of Kancheepuram district, Tamil Nadu

Shrivastava¹,

Shrivastava²,

S³

2017

Int J Med Sci Public Health

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the health-care delivery system in India. [1,2] Hypertension has been identified as the direct cause of deaths in more than 55% and 25% of all stroke and all coronary heart disease-related deaths reported in India.[3] Even on a global scale, hypertension is one of the most important causes of premature death as per the World Health Organization. [4] Current estimates reveal that hypertension affects more than 30% of adults with age 25 years and above which accounts for almost 1 billion people worldwide.[5] Furthermore, as per trend analysis, it has been estimated that more than 20 million cardiovascular deaths will be attributed to hypertension, by the year 2030, of which in excess of four-fifths will be from Background: Hypertension exerts a massive public health burden on cardiovascular health and health system in India. Objectives: The aim of this study is to assess the level of treatment adherence among the known hypertensive patients in a rural community and identify the determinants for non-adherence to treatment among them. Materials and Methods: A communitybased cross-sectional descriptive study was conducted for 2 months in Sembakkam and Kottamedu villages under the rural field practice area of a medical college among known cases of hypertension diagnosed and initiated on antihypertensive therapy at least 3 months back. A total of 170 hypertensive patients were included as study participants using random sampling, and the desired information was obtained using a semi-structured schedule, and details about treatment adherence based on the Morisky Medication Adherence Scale. Ethical clearance was obtained from the Institutional Ethics Committee before the start of the study. Written informed consent was obtained from the study participants before eliciting any information from them. Statistical analysis was done using SPSS version 18. Frequency distributions were calculated for all the variables. Chi-square test was used for testing the significance of association at P = 0.05. Results: Among the study participants, 81 (47.6%) had good medication adherence, whereas 89 (52.4%) had poor adherence. A statistically significant association was observed between indulging in regular physical activity and use of salt-restricted diet and a good level of treatment adherence. Poor adherence to treatment was found more commonly among patients who were prescribed multiple antihypertensive drugs and those with more than once daily dose formulation. Conclusion: The study indicates that prevalence of treatment adherence among hypertensive patients in rural areas of Tamil Nadu was only 47.6% and there is a lot of scope for improvement. The study has also identified the crucial factors responsible for non-compliance to antihypertensive treatment which can assist the health-care policy makers to formulate a comprehensive strategy to achieve adequate compliance.

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Predictors of adherence to antihypertensive medication in northern United Arab Emirates

Cited by 30 publications

References 27 publications

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

Assessment of Blood Pressure Control among Hypertensive Patients in Southwest Ethiopia

Investigation of variables associated with medication nonadherence in patients with hypertension

A community-based study to assess the treatment adherence and its determinants among hypertensive patients residing in a rural area of Kancheepuram district, Tamil Nadu

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