AimEvidence shows that early mobilization according to the Enhanced Recovery After Surgery guideline promotes postoperative recovery in gastrointestinal cancer patients undergoing gastrointestinal surgery. However, compliance with the guideline in clinical settings remains low. This study aimed to investigate the factors influencing early mobilization after surgery.MethodsA prospective research design was used. Data from 470 patients with gastrointestinal cancer who underwent gastrointestinal surgery between February 2021 and July 2022 were collected.ResultsMore than half (53.6%) of the patients met the criteria for early mobilization. Females (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.02–2.29), age 〉70 years (OR, 1.76; 95% CI, 1.09–2.86), low level of education (OR, 1.98; 95% CI, 1.12–3.95), and ≥4 catheters (OR, 1.86; 95% CI, 1.25–2.76) were barriers to early mobilization.ConclusionsSex, age, education, and the number of catheters were found to be significant factors associated with non‐early mobilization after gastrointestinal surgery. Geriatr Gerontol Int 2024; ••: ••–••.