Predictors of acquiring a nosocomial bloodstream infection on extracorporeal membrane oxygenation

Steiner, Craig; Stewart, Dan L.; Bond, Sheldon J.; Hornung, Carlton A.; McKay, Victor

doi:10.1053/jpsu.2001.21609

Cited by 77 publications

(74 citation statements)

References 9 publications

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“…We could not see any significant trends within the WBC, ANC or I/T ratio, which confirms previous data [4]. Thrombocytopenia, being a complication of ECLS itself, was not useful as a marker of impending or persisting infection.…”

Section: Discussionsupporting

confidence: 86%

“…Steiner et al [4] showed a BSI incidence of 3.4% (7/202 neonates). CoNS (5 of 7) were the most common pathogen.…”

Section: Discussionmentioning

confidence: 97%

“…Reported center-specific survival rates vary between 58 and 70% [3][4][5][6] (Table 3), whereas the ELSO survival to discharge or transfer is 65% [1] (Table 2). The definition of contaminant in blood cultures differs greatly among published reports and this lack of common definition underlines the potential heterogeneity of the ELSO data.…”

Section: Discussionmentioning

confidence: 99%

“…In 2005, the Extracorporeal Life Support Organization (ELSO) reported an incidence of 8.8% culture proven infections in 29.993 neonatal and pediatric patients since recording [1]. Several reviews have reported incidences between 0.9 and 19.5% [2][3][4][5][6]. Diagnosing sepsis clinically is challenging in patients on ECLS.…”

Section: Introductionmentioning

confidence: 99%

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Bloodstream infections in pediatric ECLS: usefulness of daily blood culture monitoring and predictive value of biological markers. The British Columbia experience

et al. 2009

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Compared with ELSO, the studied BSI incidence was higher with a comparable mortality. We speculate that our BSI rate is explained by underreporting of "contaminants" in the literature, the use of broad-spectrum antibiotic prophylaxis and a higher yield with daily monitoring BC. We support daily surveillance blood cultures as an alternative to antibiotic prophylaxis in the management of patients on ECLS.

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Section: Discussionsupporting

confidence: 86%

“…Steiner et al [4] showed a BSI incidence of 3.4% (7/202 neonates). CoNS (5 of 7) were the most common pathogen.…”

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bloodstream infections in pediatric ECLS: usefulness of daily blood culture monitoring and predictive value of biological markers. The British Columbia experience

et al. 2009

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“…Impact of infection on results of ECMO therapy is controversial. Some authors suggest that sepsis or nosocomial infection correlate with risk of patient death [23,24] whereas other reported no such link [25,26]. Patients surviving ECMO therapy are significantly longer hospitalised and spend more time in ICU.…”

Section: Discussionmentioning

confidence: 99%

Veno-arterial extracorporeal membrane oxygenation for short-term mechanical circulation support in adults with cardiogenic shock: a single centre experience

Musiał

Moncznik

et al. 2016

Kardiol Pol

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A b s t r a c tBackground: Patients suffering from cardiogenic shock, with no response to conventional therapy, may significantly improve when put on support devices such as extracorporeal membrane oxygenation (ECMO), which maintains systemic and pulmonary circulation, and decongests the heart. This publication presents authors' own experience in qualifying and treating patients with cardiogenic shock, with the use of veno-arterial (VA) ECMO modality. Aim:The main goal of the study was to analyse factors influencing outcome of VA ECMO therapy in patients with cardiogenic shock. Survival data were compared for patients surviving treatment (n = 12, 41%), and for patients who died while VA ECMO. Methods:Retrospective study included all patients treated between February 2009, when ECMO was first used in the clinic, and March 2015. Of those, 29 patients were treated with VA ECMO for respiratory support. Mean patient age was 42 years; 19 (66%) patients were male, and 10 (34%) patients were female.Results: Total in-hospital mortality rate was 59% (17/29). No difference was observed as to patient age, sex, body height, mode of hospital admission, comorbidities or left ventricular ejection fraction at hospital admission, when comparing survivors and patients who died despite treatment. The following parameters were analysed: number of days on VA ECMO, troponin levels during first days from treatment onset, platelet transfusions, and duration of mechanical ventilation. No significant differences were observed between the groups. Surviving patients were significantly longer hospitalised (p = 0.016), including a longer stay in the intensive care unit (p = 0.03). Conclusions:VA ECMO is an acceptable therapy for patients in a severe state of cardiogenic shock. In-hospital mortality rate was 59%, and 41% patients (12 subjects) were successfully treated with VA ECMO in course of cardiogenic shock.

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Extracorporeal Membrane Oxygenation (ECMO)/Extracorporeal Carbon Dioxide Removal (ECCO2R)

Werner

Park

2016

Principles of Adult Surgical Critical Care

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Predictors of acquiring a nosocomial bloodstream infection on extracorporeal membrane oxygenation

Cited by 77 publications

References 9 publications

Bloodstream infections in pediatric ECLS: usefulness of daily blood culture monitoring and predictive value of biological markers. The British Columbia experience

Bloodstream infections in pediatric ECLS: usefulness of daily blood culture monitoring and predictive value of biological markers. The British Columbia experience

Veno-arterial extracorporeal membrane oxygenation for short-term mechanical circulation support in adults with cardiogenic shock: a single centre experience

Extracorporeal Membrane Oxygenation (ECMO)/Extracorporeal Carbon Dioxide Removal (ECCO2R)

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