Predictors for 2-year outcome of major depressive episode

Szádóczky, Erika; Rózsa, Sándor; Zámbori, János; Füredi, János

doi:10.1016/j.jad.2004.05.001

Cited by 52 publications

(34 citation statements)

References 25 publications

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“…16,21,33 In the present study, the sociodemographic domain did not result in statistically significant predictive variables (i.e., age, sex, marital status, and level of education). Some studies, however, identified age as a predictor of slower response to treatment, 7,26 while others found no association between age and treatment outcome. 7,8 Level of education may be positively associated with treatment outcome.…”

Section: Discussionmentioning

confidence: 99%

“…Some studies, however, identified age as a predictor of slower response to treatment, 7,26 while others found no association between age and treatment outcome. 7,8 Level of education may be positively associated with treatment outcome. 9 Other examples of potential demographic predictors of treatment outcome include gender, marital Figure 1 Linear slope estimates for the LNS Â Treatment interaction.…”

Section: Discussionmentioning

confidence: 99%

“…An extensive literature review on response predictors is beyond the scope of this study, but we found a few studies that have produced notable results on predictors within one type of treatment for depression. [7][8][9] These studies reported that patient age did not interfere with clinical outcome in adults with depression treated with antidepressants. They also found that depression severity in inpatients was negatively associated with patient discharge, while physical health status and level of education were positively associated with discharge.…”

Section: Introductionmentioning

confidence: 98%

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Predictors of response in the treatment of moderate depression

Bastos

Guimarães

Trentini

2016

Rev. Bras. Psiquiatr.

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Objective: To identify neurocognitive and sociodemographic variables that could be associated with clinical response to three modalities of treatment for depression, as well as variables that predicted superior response to one treatment over the others. Method: The present study derives from a research project in which depressed patients (n=272) received one of three treatments -long-term psychodynamic psychotherapy (n=90), fluoxetine therapy (n=91), or a combination thereof (n=91) -over a 24-month period. Results: Sociodemographic variables were not found to be predictive. Six predictive neurocognitive variables were identified: three prognostic variables related to working memory and abstract reasoning; one prescriptive variable related to working memory; and two variables found to be moderators. Conclusions:The results of this study indicate subgroups of patients who might benefit from specific therapeutic strategies and subgroups that seem to respond well to long-term psychodynamic psychotherapy and combined therapy. The moderators found suggest that abstract reasoning and processing speed may influence the magnitude and/or direction of clinical improvement.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

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Predictors of response in the treatment of moderate depression

Bastos

Guimarães

Trentini

2016

Rev. Bras. Psiquiatr.

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“…After providing patients with a complete description of the study, written informed consent was obtained from each of them. The Hungarian version of Structured Clinical Interview for DSM-IV Axis I and Axis II disorders (SCID-I-II) (Szádóczky et al 2004(Szádóczky et al , 2006 was then administered to confirm the diagnosis of BPD and to assess comorbid disorders. Twelve of ninety-two participants were eliminated by the diagnostic interview: eight because they were found to have disorders excluded from this study, as above, and four, because they met less than five BPD diagnostic criteria.…”

Section: Subjectsmentioning

confidence: 99%

Characteristics and Development of Nonsuicidal Super Self-Injury Among Borderline Inpatients

Merza¹,

Papp²,

Molnár³

et al. 2017

Psychiat Danub

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“…Searching for predictive factors influencing the outcome of a 2-year prospective antidepressant follow-up study, Szadoczky et al [11] found that a high level of trait anxiety predicted a high level of depressive symptoms at the end of the study.…”

Section: Introductionmentioning

confidence: 99%

Trait Anxiety and Defensive Functioning in Relation to Antidepressant Treatment Outcome

Sukul¹,

Birkenhäger²,

Broek³

et al. 2009

Psychopathology

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Background: Depression can occur in patients with or without trait anxiety. Although it is assumed that assessment of defenses can be useful in planning biological treatment, no studies have confirmed this hypothesis. In this study we focus on the relation between trait anxiety and defensive functioning, and on the combined influence of these personality characteristics on response to antidepressants among inpatients with a major depressive episode. Methods: Major depressive episode was diagnosed using the Schedule for Affective Disorders and Schizophrenia (SADS) and the severity of the depression was measured with the Hamilton Rating Scale for Depression (HAM-D). The level of trait anxiety was assessed using a questionnaire with 34 questions pertaining to trait anxiety. The Defense Style Questionnaire (DSQ 88) was used to assess defensive functioning followed by a weighted overall defensive functioning score (ODF). Partial correlations and multiple regression analyses were used to analyze the data. Results: The final sample included 85 patients. A significant negative effect of trait anxiety by ODF (p: 0.000) was found on the outcome score, i.e. the combination of a high score on trait anxiety and a low score on the ODF resulted in a significantly higher final score on the HAM-D. Conclusions: The most important finding in this study is that the combination of a high level of trait anxiety and immature defensive functioning evidently had a negative effect on antidepressant treatment outcome.

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Predictors for 2-year outcome of major depressive episode

Cited by 52 publications

References 25 publications

Predictors of response in the treatment of moderate depression

Predictors of response in the treatment of moderate depression

Characteristics and Development of Nonsuicidal Super Self-Injury Among Borderline Inpatients

Trait Anxiety and Defensive Functioning in Relation to Antidepressant Treatment Outcome

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