Predictors and Outcome of Severe Dengue Illness in Children

Alikunju, Sheela Theparambil; Thuruthiyath, Nithya; Premdas, Alok Kanjhoor; Jose, Rose Mary

doi:10.14260/jemds/2020/143

Cited by 1 publication

(3 citation statements)

References 15 publications

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“…Mishra et al [7] and Padmanabhan et al [16] stated that raised hematocrit was statistically not significant in severe dengue which does not correlate with our study. Sheela et al [8] stated in their study that when non-severe dengue and severe dengue were compared, platelet count, serum sodium, albumin, serum glucose, RFT, and coagulation profile as predictors which correlates with our study. Similar observations were made by Kumar et al [18].…”

Section: Discussionsupporting

confidence: 83%

“…A total of 104 patients were included in the study who were grouped as non-severe and severe as per the WHOs operational guidelines for diagnosis and treatment [5] and handbook for clinical management of dengue [6]. Results reported by our study were similar to the results reported by Mishra et al [7] and Sheela et al [8] in terms of number of patients in both groups.…”

Section: Discussionsupporting

confidence: 82%

“…All these parameters were significantly associated with severe dengue. Studies by Kularatnam et al [23], Mishra et al [7], Sheela et al [8], Kumar et al [18], and Somasaundaram et al [14] agreed with the association of raised liver transaminases with severe dengue fever. Jayarajah et al [15], reported that low white blood cell (WBC) and low platelet counts to be significantly associated with DHF but liver enzyme derangement did not predict DHF.…”

Section: Discussionmentioning

confidence: 69%

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A study on predictors of severe dengue in pediatric patients in a tertiary care hospital in Telangana

Reddy¹,

Musali²

2021

Indian J Child Health

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Dengue is an arthropod borne viral disease which has a huge impact on human health as well as the global and national economies. It is widespread throughout the tropics, with local variations in risk influenced by rainfall, temperature, relative humidity, and unplanned rapid urbanization [1]. A total of 390 million dengue virus infections occur per year of which 96 million manifests clinically with varying severity [2]. A study on the prevalence of dengue estimates that 3.9 billion people are at risk of infection with dengue viruses. Despite a risk of infection existing in 129 countries [3], 70% of the actual burden is in Asia [2]. In 2020, dengue continues to affect several countries, with reports of increase in the numbers of cases in number of countries including India. Bhatt et al. showed a discrepancy between reported and modeled dengue incidence, which was particularly high for India. According to their estimates, India contributed 34 of 96 million apparent global dengue infections, a number which stands in stark contrast to the 12,484 reported cases from India to the World Health Organization (WHO) in the same year. Such a mismatch was also reported for India in another study, in which the actual numbers of dengue cases were 282 times the number reported by the national vector-borne disease control program [4].Dengue is a systemic and dynamic disease. After the incubation period, the illness begins abruptly and is followed by the three phases; febrile, critical, and recovery phase [5]. The WHO classifies dengue into two major categories: Dengue (with/ without warning signs) and severe dengue. This subclassification

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 82%