2009
DOI: 10.1016/j.pmrj.2008.11.002
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Predictive Value of the Disorders of Consciousness Scale (DOCS)

Abstract: For persons with prolonged disorders of consciousness, the findings indicate that evidence-based prognostication for individual patients is possible. The implications for research are that the DOCS can be used as a meaningful, reliable, and valid primary outcome to measure treatment effects in clinical trials. The evidence indicates further that DOCS measures merit inclusion in future research that aims to develop multivariate prognostication models.

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Cited by 14 publications
(14 citation statements)
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“…Very few articles measured change on the SSAM ( n = 1) or DOCS ( n = 2) (Table 4). The two papers relating to the DOCS descriptively reported change during inpatient brain injury rehabilitation of a large sample showing change over time (Pape et al, 2009) and three detailed case studies showing change over time and responsiveness to medication changes influencing arousal (Pape, Senno, Guernon, & Kelly, 2005b). The regular serial assessment over time using the DOCS in the three cases highlights the value of regular assessment for intervention planning to maximise consciousness (Pape et al, 2005b).…”
Section: Resultsmentioning
confidence: 99%
“…Very few articles measured change on the SSAM ( n = 1) or DOCS ( n = 2) (Table 4). The two papers relating to the DOCS descriptively reported change during inpatient brain injury rehabilitation of a large sample showing change over time (Pape et al, 2009) and three detailed case studies showing change over time and responsiveness to medication changes influencing arousal (Pape, Senno, Guernon, & Kelly, 2005b). The regular serial assessment over time using the DOCS in the three cases highlights the value of regular assessment for intervention planning to maximise consciousness (Pape et al, 2005b).…”
Section: Resultsmentioning
confidence: 99%
“…During rehabilitation hospitalization, neurobehavioral evaluations using the Disorders of Consciousness Scale-25 (DOCS-25) [ 17 19 ] were conducted weekly until recovery of consciousness or completion of a sixth DOCS evaluation or discharge from the rehabilitation facility, whichever came first. The DOCS-25 is a bedside test administered by allied health clinicians [ 20 ]. Best behavioral responses, elicited with the 25 test stimuli, are scored according to a 3-point scale (0 = no response, 1 = generalized response, and 2 = localized response).…”
Section: Methodsmentioning
confidence: 99%
“…The DOCS minimal clinically important difference (MCID) is 2.58 which corresponds to the smallest amount of clinically meaningful DOCS change [ 21 ]. A final important note is that the DOCS also has strong prognostic validity for predicting recovery of consciousness for multiple time points within the first year of recovery [ 22 ] and independence with expressing needs 1 year after severe BI [ 23 ].…”
Section: Methodsmentioning
confidence: 99%
“…Cortical stimulation has also been performed with rTMS in a 26-year-old male remaining vegetative about 10 months after traumatic brain injury [65]. After a 6-week rTMS protocol of the right dorsolateral prefrontal cortex (30 sessions per day, 5 days per week), no adverse effect was observed and a Disorders of Consciousness Scale found a non-significant trend of neurobehavioral gains [66].…”
Section: Non-dbs Targets and Improvement Of Altered Arousal And Conscmentioning
confidence: 99%