Predictive value of SYNTAX score II for clinical outcomes in cardiogenic shock underwent primary percutaneous coronary intervention; a pilot study

Abstract

SYNTAX Score II (SSII) connects clinical variables with coronary anatomy. We investigated the prognostic value of SSII in patients with ST segment elevated myocardial infarction (STEMI) complicated with cardiogenic shock treated with primary percutaneous coronary intervention (PPCI). In this retrospective analysis, we evaluated the in-hospital prognostic impact of SSII on 492 patients with STEMI complicated with cardiogenic shock treated with PPCI. Patients were stratified by tertiles of SSII, in-hospital clinical outcomes were compared between those groups. In-hospital univariate analysis revealed higher rates of in-hospital death for patients with SSII in tertile 3, as compared to patients with SSII in tertile 1 (OR 17.4, 95% CI 10.0-30.2, p < 0.001). After adjustment for confounding baseline variables, SSII in tertile 3 was associated with 6.2-fold hazard of in-hospital death (OR 6.2, 95% CI 2.6-14.1, p < 0.001). SSII in patients with STEMI complicated with cardiogenic shock treated with PPCI provide an independent prognostic marker of in-hospital outcomes. Our data suggests SSII to be a simple, feasible and clinically applicable tool for rapid risk stratification in patients with STEMI complicated with cardiogenic shock treated with PPCI.

Comparison of the Predictive Roles of Risk Scores of In-Hospital Major Adverse Cardiovascular Events in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

“…Hayiroglu et al [17] reported that SS-II provides a prognostic value for in-hospital mortality and MACE in STEMI patients who had complications related to cardiogenic shock. This result indicates that SS-II is predictive not only for long-term outcomes but also for in-hospital outcomes of STEMI patients.…”

“…In addition, SS-II is superior to SS in the prediction of in-hospital mortality in patients with STEMI complicated with cardiogenic shock treated with primary PCI. Hayiroglu et al [17] showed that SS-II is not favorable for predicting in-hospital target lesion revascularization, stent thrombosis, or recurrent myocardial infarction. Our study, however, focused on NSTEMI patients and showed that SS-II has a prognostic value for in-hospital mortality and MACE in NSTEMI patients treated with primary PCI.…”

Percutaneous coronary intervention assisted by invasive mechanical ventilation and intra-aortic balloon pump for acute myocardial infarction with cardiogenic shock: Retrospective cohort study and meta-analysis

“…Hayıroğlu et al found that higher SYNTAX score II was associated with poor prognosis [29]. Considering the impact of coronary anatomy on prognosis, we calculated that the proportion of three-vessel lesions in the meta-analysis for IABP + PCI (315 people) was 52.1%, which was lower than that in our cohort study (65%).…”

Cardiovascular imaging 2018 in the International Journal of Cardiovascular Imaging

“…They found that patients in tertile 3 had a 6.2-fold hazard of in-hospital death, and therefore concluded that the Syntax II Score is a simple, feasible and clinically applicable tool for rapid risk stratification in this patient population [2].…”

“…The team of Hayiroglu et al investigated the prognostic value of Syntax Score II in STEMI patients complicated with cardiogenic shock and treated with primary PCI [2]. 492 patients were included in the retrospective analysis and subdivided in three tertiles based on their Syntax Score.…”