Predictive value of hematological parameters in testicular salvage: A 12-year retrospective review

Abstract

PurposeThis study aimed to evaluate the predictive value of preoperative hematological parameters for testicular salvage in patients with testicular torsion.MethodsClinical data of patients with testicular torsion treated at Shenzhen Children's Hospital from January 2010 to December 2021 were analyzed retrospectively. The data collected included age, symptom duration, degree of spermatic cord torsion, the surgical approach adopted, hematological parameters, and ultrasound results during postoperative follow-up.ResultsThe study participants were classified into three groups as follows: the successful testicular salvage group (n = 43), failed testicular salvage group (n = 124), and control group (n = 100). Univariate analysis showed that testicular salvage was related to patient age, duration of symptoms, spermatic cord torsion degree, white blood cell count, lymphocyte count, monocyte count, platelet-lymphocyte ratio, and neutrophil-lymphocyte ratio. However, multivariate analysis revealed that symptom duration (OR = 0.948, P < 0.001), degree of spermatic cord torsion (OR = 0.994, P < 0.001), and monocyte count (OR = 0.020, P = 0.011) were independent risk factors for testicular torsion salvage. The monocyte count in the failed salvage group was significantly higher than in the successful salvage and control groups (P < 0.01).ConclusionMonocyte count is an independent predictor of testicular salvage. Therefore, clinicians can predict the success rate of testicular salvage in patients with testicular torsion based on the monocyte count.

A nomogram for predicting risk factors of testicular salvage after testicular torsion in children

“…This causes testicular blood flow to either decrease or stop entirely. If the rotated state is not corrected in time, it could easily cause testicular ischemic damage and even necrosis 3 . Some studies have pointed out that the success rate of testicular rescue within 6 h after testicular torsion is 90%–100% and drops to 0%–10% after 12–24 h 4 .…”

“…If the rotated state is not corrected in time, it could easily cause testicular ischemic damage and even necrosis. 3 Some studies have pointed out that the success rate of testicular rescue within 6 h after testicular torsion is 90%-100% and drops to 0%-10% after 12-24 h. 4 In patients with testicular torsion, surgical exploration must be performed as soon as possible to restore the normal anatomical state of the testis and spermatic cord. Moreover, orchiectomy or orchiopexy should be considered based on testicular vitality.…”

Factors Determining Testicular Torsion and Consequent Orchiectomy in Pediatric Patients Presenting With Scrotal Pain

“…[6][7][8] The annual incidence of TT is approximately from 3.5 to 25 per 100,000 person-years for boys aged younger than 18 years. 1,7,9 Two peaks of the age-specific incidence are in young children and adolescents 3,[7][8][9] ; the incidence decreases after age 18 years. 1 Testicular torsion may lead to testicular ischemic necrosis and permanent testicular damage or consequent orchiectomy in 32% to 64% of patients if testicular blood reperfusion is impaired.…”

“…Testicular torsion must be distinguished from SP of other etiologies 3–5 because TT/detorsion is an ischemia–reperfusion process of the testis, which is a time-critical urological emergency requiring immediate diagnosis and surgical intervention 6–8 . The annual incidence of TT is approximately from 3.5 to 25 per 100,000 person-years for boys aged younger than 18 years 1,7,9 . Two peaks of the age-specific incidence are in young children and adolescents 3,7–9 ; the incidence decreases after age 18 years 1…”

“…The annual incidence of TT is approximately from 3.5 to 25 per 100,000 person-years for boys aged younger than 18 years 1,7,9 . Two peaks of the age-specific incidence are in young children and adolescents 3,7–9 ; the incidence decreases after age 18 years 1…”