Predictive value of galectin-1 in the development and progression of HIV-associated lymphoma

Vase, MajaØlholm; Ludvigsen, Maja; Bendix, Knud; Dutoit, Stephen Hamilton; Hjortebjerg, Rikke; Petruskevicius, Irma; Møller, Michael; Pedersen, Gert Frølund; Denton, Paul W.; Honoré, Bent; Rabinovich, Gabriel A.; Larsen, Carsten Schade; d’Amore, Francesco

doi:10.1097/qad.0000000000001622

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…However, there are different opinions regarding the role of galectin-1. In HIV-associated DLBCL, patients with a higher intratumoral galectin-1 expression level have a higher survival rate ( 107 ). In addition, galectin-1 induced the death of ALCL cells, and this effect was more obvious when combined with CD30 pre-stimulation ( 108 ).…”

Section: Galectin-1mentioning

confidence: 99%

Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy?

Shi

Tang

et al. 2022

Front. Oncol.

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The galectin family of proteins has high affinity with β-galactoside-containing glycans. These proteins participate in cell growth and differentiation, cell adhesion, cell signal transduction, cell apoptosis, and other cellular activities. In recent years, a large number of studies have described the expression and correlation of galectins in different tumors. Each member of the family plays a vital role in tumor growth, progression, angiogenesis, adhesion, and tumor immune escape. Studies on the roles of galectins in lymphoma have mainly involved galectin-1, -3, -7, and -9. The results suggest that galectins may become novel targets for precise tumor treatment. This article reviews current research progress regarding galectins in lymphoma and provides new ideas for exploring them as novel targets for treating lymphoma and other important medical issues.

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Section: Galectin-1mentioning

confidence: 99%